Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| orn Rv2511 |
mtbc0_002673 |
oligoribonuclease | Oligoribonuclease. Pfam: RNase_T (PF00929.32). | RNase_T |
Resolved |
| Rv2512a Rv2512a |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 7jt2-assembly1_q 70S ribosome stalled on long mRNA with ArfB bound in (prob 0.03, TM 0.26). | Still unknown | |
| Rv2512c Rv2512c |
- |
insertion sequence element IS1081 transposase | Insertion sequence element IS1081 transposase. Pfam: Transposase_mut (PF00872.25). | Transposase_mut |
Resolved |
| Rv2513 Rv2513 |
mtbc0_002676 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2514c Rv2514c |
mtbc0_002677 |
hypothetical protein | DUF4411 family protein. | DUF4411 |
Family assigned |
| Rv2515c Rv2515c |
mtbc0_002678 |
hypothetical protein | XRE family transcriptional regulator. Pfam: HTH_3 (PF01381.29), Peptidase_M78 (PF06114.20). | HTH_3 Peptidase_M78 |
Family assigned |
| Rv2516c Rv2516c |
mtbc0_002679 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 7b90-assembly1_E Circular permutant of ribosomal protein S6, P54-55 tr (prob 0.99, TM 0.64). | Still unknown | |
| Rv2517c Rv2517c |
mtbc0_002680 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 7ax2-assembly1_A Crystal structure of the computationally designed Sco (prob 0.51, TM 0.79). | Still unknown | |
| ldtB Rv2518c |
mtbc0_002681 |
L,D-transpeptidase LdtB | L%2CD-transpeptidase LdtMt2. Pfam: Big_10 (PF17964.8), YkuD (PF03734.20). | Big_10 YkuD |
Resolved |
| PE26 Rv2519 |
- |
PE family protein PE26 | PE family protein PE26. Pfam: PE (PF00934.26), PGRS (PF21526.3), PE-PGRS_C (PF20729.3). | PE PGRS PE-PGRS_C |
Family assigned |
| Rv2520c Rv2520c |
mtbc0_002684 |
membrane protein | Conserved hypothetical protein; DUF domain(s) DUF3618. Function unknown. | DUF3618 |
Still unknown |
| bcp Rv2521 |
mtbc0_002685 |
peroxiredoxin | Thioredoxin-dependent thiol peroxidase. Pfam: AhpC-TSA (PF00578.28), Redoxin (PF08534.17). | AhpC-TSA Redoxin |
Resolved |
| Rv2522c Rv2522c |
mtbc0_002686 |
hypothetical protein | Dipeptidase. Pfam: Peptidase_M20 (PF01546.34), M20_dimer (PF07687.20). | Peptidase_M20 M20_dimer |
Resolved |
| acpS Rv2523c |
mtbc0_002687 |
holo-ACP synthase | Holo-ACP synthase. Pfam: ACPS (PF01648.26). | ACPS |
Resolved |
| fas Rv2524c |
mtbc0_002688 |
fatty acid synthase | Fatty acid synthase. Pfam: SAT (PF16073.11), FAS_AT_central (PF22690.2), Fas1-AflB-like_hel (PF08354.16), SBS_FAS (PF18094.8), MaoC_dehydratas (PF01575.26), Acyl_transf_1 (PF00698.27), ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29). | SAT FAS_AT_central Fas1-AflB-like_hel SBS_FAS MaoC_dehydratas Acyl_transf_1 ketoacyl-synt Ketoacyl-synt_C |
Resolved |
| Rv2525c Rv2525c |
mtbc0_002689 |
hypothetical protein | DUF1906 domain-containing protein. Pfam: Rv2525c_GlyHyd-like (PF08924.18). | Rv2525c_GlyHyd-like |
Family assigned |
| vapB17 Rv2526 |
mtbc0_002690 |
antitoxin VapB17 | Type II toxin-antitoxin system VapB family antitoxin. Pfam: VapB_antitoxin (PF09957.16). | VapB_antitoxin |
Family assigned |
| vapC17 Rv2527 |
mtbc0_002691 |
ribonuclease VapC17 | PIN domain-containing protein. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| mrr Rv2528c |
mtbc0_002692 |
restriction system protein | Restriction endonuclease. Pfam: Mrr_N (PF14338.13), Mrr_cat (PF04471.19), NA-iREase1 (PF22722.3), Mrr_cat_2 (PF13156.13). | Mrr_N Mrr_cat NA-iREase1 Mrr_cat_2 |
Resolved |
| Rv2529 Rv2529 |
- |
hypothetical protein | Contains ERCC4 (PF02732.22), Lsr2_DNA-bd (PF23359.2) domain(s); putative function inferred from the domain architecture. | ERCC4 Lsr2_DNA-bd |
Family assigned |
| vapB39 Rv2530A |
- |
antitoxin VapB39 | Antitoxin VapB39. | Resolved | |
| vapC39 Rv2530c |
mtbc0_002695 |
ribonuclease VapC39 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| Rv2531c Rv2531c |
- |
amino acid decarboxylase | Amino acid decarboxylase. Pfam: OKR_DC_1 (PF01276.27). | OKR_DC_1 |
Resolved |
| Rv2532c Rv2532c |
mtbc0_002698 |
hypothetical protein | Antitermination protein NusB. | Resolved | |
| nusB Rv2533c |
mtbc0_002699 |
N utilization substance protein B | Transcription antitermination factor NusB. Pfam: NusB (PF01029.24). | NusB |
Resolved |
| efp Rv2534c |
- |
elongation factor P | Elongation factor P. Pfam: EFP_N (PF08207.19), EFP (PF01132.28), Elong-fact-P_C (PF09285.18). | EFP_N EFP Elong-fact-P_C |
Resolved |
| pepQ Rv2535c |
mtbc0_002701 |
cytoplasmic peptidase PepQ | Xaa-Pro peptidase family protein. Pfam: Creatinase_N (PF01321.25), Peptidase_M24 (PF00557.30). | Creatinase_N Peptidase_M24 |
Family assigned |
| Rv2536 Rv2536 |
mtbc0_002702 |
transmembrane protein | B-4DMT family transporter. | Family assigned | |
| aroD Rv2537c |
mtbc0_002703 |
3-dehydroquinate dehydratase | Type II 3-dehydroquinate dehydratase. Pfam: DHquinase_II (PF01220.25). | DHquinase_II |
Resolved |
| aroB Rv2538c |
mtbc0_002704 |
3-dehydroquinate synthase | 3-dehydroquinate synthase. Pfam: Fe-ADH_2 (PF13685.13), DHQ_synthase (PF01761.27), DHQS_C (PF24621.3). | Fe-ADH_2 DHQ_synthase DHQS_C |
Resolved |
| aroK Rv2539c |
mtbc0_002705 |
shikimate kinase | Shikimate kinase AroK. Pfam: AAA_33 (PF13671.13), AAA_18 (PF13238.13), SKI (PF01202.29). | AAA_33 AAA_18 SKI |
Resolved |
| aroF Rv2540c |
mtbc0_002706 |
chorismate synthase | Chorismate synthase. Pfam: Chorismate_synt (PF01264.27). | Chorismate_synt |
Resolved |
| Rv2541 Rv2541 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3zbh-assembly1_B Geobacillus thermodenitrificans EsxA crystal form I (prob 1.00, TM 0.78). | Still unknown | |
| Rv2542 Rv2542 |
mtbc0_002708 |
hypothetical protein | Alpha/beta hydrolase family protein. Pfam: Abhydrolase_8 (PF06259.19). | Abhydrolase_8 |
Family assigned |
| lppA Rv2543 |
mtbc0_002709 |
lipoprotein LppA | LppA family lipoprotein. Pfam: LppA (PF16708.11). | LppA |
Family assigned |
| lppB Rv2544 |
mtbc0_002711 |
lipoprotein LppB | LppA family lipoprotein. Pfam: LppA (PF16708.11). | LppA |
Family assigned |
| vapB18 Rv2545 |
mtbc0_002712 |
antitoxin VapB18 | Type II toxin-antitoxin system VapB family antitoxin. Pfam: VapB_antitoxin (PF09957.16). | VapB_antitoxin |
Family assigned |
| vapC18 Rv2546 |
mtbc0_002713 |
ribonuclease VapC18 | PIN domain nuclease. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| vapB19 Rv2547 |
mtbc0_002714 |
antitoxin VapB19 | CopG family transcriptional regulator. Pfam: RHH_1 (PF01402.28). | RHH_1 |
Family assigned |
| vapC19 Rv2548 |
mtbc0_002715 |
ribonuclease VapC19 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| Rv2548A Rv2548A |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| vapC20 Rv2549c |
mtbc0_002717 |
ribonuclease VapC20 | Type II toxin-antitoxin system toxin 23S rRNA-specific endonuclease VapC20. Pfam: PIN (PF01850.28). | PIN |
Resolved |
| vapB20 Rv2550c |
mtbc0_002718 |
antitoxin VapB20 | Type II toxin-antitoxin system antitoxin VapB20. Pfam: RHH_1 (PF01402.28). | RHH_1 |
Resolved |
| Rv2551c Rv2551c |
mtbc0_002719 |
hypothetical protein | A24 family peptidase. Pfam: Peptidase_A24 (PF01478.24). | Peptidase_A24 |
Family assigned |
| aroE Rv2552c |
mtbc0_002720 |
shikimate 5-dehydrogenase | Shikimate dehydrogenase. Pfam: Shikimate_dh_N (PF08501.17), SDH_C (PF18317.7). | Shikimate_dh_N SDH_C |
Resolved |
| mltG Rv2553c |
mtbc0_002721 |
membrane protein | Endolytic transglycosylase MltG. Pfam: YceG (PF02618.22). | YceG |
Resolved |
| ruvX Rv2554c |
mtbc0_002722 |
Holliday junction resolvase | Holliday junction resolvase RuvX. Pfam: RuvX (PF03652.21). | RuvX |
Resolved |
| alaS Rv2555c |
mtbc0_002723 |
alanine--tRNA ligase | Alanine--tRNA ligase. Pfam: tRNA-synt_2c (PF01411.25), tRNA_SAD (PF07973.20), DHHA1 (PF02272.25). | tRNA-synt_2c tRNA_SAD DHHA1 |
Resolved |
| Rv2556c Rv2556c |
mtbc0_002724 |
hypothetical protein | Secondary thiamine-phosphate synthase enzyme YjbQ. Pfam: YjbQ (PF01894.23). | YjbQ |
Resolved |
| Rv2557 Rv2557 |
- |
hypothetical protein | Contains ABM (PF03992.23) domain(s); putative function inferred from the domain architecture. | ABM |
Family assigned |