Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv0997 Rv0997 |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv0997a Rv0997a |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 1ueb-assembly2_B Crystal structure of translation elongation factor P (prob 1.00, TM 0.70). | Still unknown | |
| Rv0998 Rv0998 |
mtbc0_001072 |
acetyltransferase Pat | GNAT family N-acetyltransferase. Pfam: cNMP_binding (PF00027.36), Acetyltransf_3 (PF13302.14), Acetyltransf_1 (PF00583.32). | cNMP_binding Acetyltransf_3 Acetyltransf_1 |
Family assigned |
| Rv0999 Rv0999 |
- |
hypothetical protein | Lipoprotein / outer-membrane-associated protein (lipoprotein-like beta fold); structurally solved but functionally uncharacterised fold RefSeq leaves this locus uncharacterised. | DUF5642 |
Family assigned |
| Rv1000c Rv1000c |
- |
hypothetical protein | Contains 2OG-FeII_Oxy_2 (PF13532.13) domain(s); putative function inferred from the domain architecture. | 2OG-FeII_Oxy_2 |
Family assigned |
| arcA Rv1001 |
mtbc0_001076 |
arginine deiminase | Arginine deiminase. Pfam: ADI (PF02274.23). | ADI |
Resolved |
| Rv1002c Rv1002c |
mtbc0_001077 |
dolichyl-phosphate-mannose--protein mannosyltransferase | Dolichyl-phosphate-mannose--protein mannosyltransferase. Pfam: PMT_2 (PF13231.13), PMT (PF02366.25), PMT_4TMC (PF16192.11). | PMT_2 PMT PMT_4TMC |
Resolved |
| rsmI Rv1003 |
mtbc0_001078 |
rRNA small subunit methyltransferase I | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase. Pfam: TP_methylase (PF00590.26). | TP_methylase |
Resolved |
| Rv1004c Rv1004c |
mtbc0_001079 |
membrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1005c Rv1005c |
- |
para-aminobenzoate synthase component I | Para-aminobenzoate synthase component I. Pfam: Chorismate_bind (PF00425.25). | Chorismate_bind |
Resolved |
| Rv1006 Rv1006 |
mtbc0_001081 |
hypothetical protein | Glycoside-hydrolase-like fold (GH2, PDB 5T99); putative glycosidase. | Family assigned | |
| metS Rv1007c |
mtbc0_001082 |
methionine--tRNA ligase | Methionine--tRNA ligase. Pfam: tRNA-synt_1g (PF09334.18), tRNA-synt_1 (PF00133.29), Anticodon_3 (PF19303.6). | tRNA-synt_1g tRNA-synt_1 Anticodon_3 |
Resolved |
| tatD Rv1008 |
- |
deoxyribonuclease TatD | Deoxyribonuclease TatD. Pfam: TatD_DNase (PF01026.28). | TatD_DNase |
Resolved |
| rpfB Rv1009 |
- |
resuscitation-promoting factor RpfB | Resuscitation-promoting factor RpfB. Pfam: DUF348 (PF03990.21), G5 (PF07501.18), Transglycosylas (PF06737.20). | DUF348 G5 Transglycosylas |
Resolved |
| ksgA Rv1010 |
mtbc0_001085 |
rRNA small subunit methyltransferase A | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA. Pfam: RrnaAD (PF00398.27). | RrnaAD |
Resolved |
| ispE Rv1011 |
- |
4-diphosphocytidyl-2C-methyl-D-erythritol kinase | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase. Pfam: GHMP_kinases_N (PF00288.33), GHMP_kinases_C (PF08544.19). | GHMP_kinases_N GHMP_kinases_C |
Resolved |
| Rv1012 Rv1012 |
mtbc0_001087 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| pks16 Rv1013 |
mtbc0_001088 |
polyketide synthase | Fatty acyl-AMP ligase. Pfam: AMP-binding (PF00501.35). | AMP-binding |
Resolved |
| pth Rv1014c |
mtbc0_001089 |
peptidyl-tRNA hydrolase | Aminoacyl-tRNA hydrolase. Pfam: Pept_tRNA_hydro (PF01195.26). | Pept_tRNA_hydro |
Resolved |
| rplY Rv1015c |
mtbc0_001090 |
50S ribosomal protein L25/general stress protein Ctc | 50S ribosomal protein L25/general stress protein Ctc. Pfam: Ribosomal_L25p (PF01386.25), Ribosomal_TL5_C (PF14693.12). | Ribosomal_L25p Ribosomal_TL5_C |
Resolved |
| lpqT Rv1016c |
- |
lipoprotein LpqT | Lipoprotein LpqT. Pfam: Lpp-LpqN (PF10738.16). | Lpp-LpqN |
Resolved |
| prsA Rv1017c |
mtbc0_001092 |
ribose-phosphate pyrophosphokinase | Ribose-phosphate diphosphokinase. Pfam: Pribosyltran_N (PF13793.13), Pribosyltran (PF00156.34), Pribosyl_synth (PF14572.13). | Pribosyltran_N Pribosyltran Pribosyl_synth |
Resolved |
| glmU Rv1018c |
mtbc0_001093 |
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU. Pfam: IspD (PF01128.26), NTP_transf_3 (PF12804.14), NTP_transferase (PF00483.30), Hexapep (PF00132.31). | IspD NTP_transf_3 NTP_transferase Hexapep |
Resolved |
| Rv1019 Rv1019 |
mtbc0_001095 |
transcriptional regulator | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_46 (PF21943.2). | TetR_N TetR_C_46 |
Family assigned |
| mfd Rv1020 |
mtbc0_001096 |
transcription-repair coupling factor | Transcription-repair coupling factor. Pfam: UvrB_inter (PF17757.7), CarD_TRCF_RID (PF02559.23), DEAD (PF00270.36), ResIII (PF04851.22), Helicase_C (PF00271.38), TRCF (PF03461.21). | UvrB_inter CarD_TRCF_RID DEAD ResIII Helicase_C TRCF |
Resolved |
| Rv1021 Rv1021 |
mtbc0_001097 |
nucleoside triphosphate pyrophosphohydrolase | Nucleoside triphosphate pyrophosphohydrolase. Pfam: MazG_N (PF27510.1), MazG (PF03819.23). | MazG_N MazG |
Resolved |
| lpqU Rv1022 |
mtbc0_001098 |
lipoprotein LpqU | Lytic murein transglycosylase. Pfam: SLT_2 (PF13406.12). | SLT_2 |
Resolved |
| eno Rv1023 |
mtbc0_001099 |
enolase | Phosphopyruvate hydratase. Pfam: Enolase_N (PF03952.22), Enolase_C (PF00113.29), MR_MLE_C (PF13378.13). | Enolase_N Enolase_C MR_MLE_C |
Resolved |
| Rv1024 Rv1024 |
mtbc0_001100 |
membrane protein | Septum formation initiator family protein. Pfam: DivIC (PF04977.21). | DivIC |
Family assigned |
| Rv1025 Rv1025 |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF501. Function unknown. Foldseek best (non-significant) hit: 4xku-assembly1_A E coli BFR variant Y114F (prob 0.01, TM 0.19). | DUF501 |
Still unknown |
| ppx2 Rv1026 |
mtbc0_001102 |
hypothetical protein | Exopolyphosphatase Ppx2. Pfam: Ppx-GppA (PF02541.23). | Ppx-GppA |
Resolved |
| kdpE Rv1027c |
mtbc0_001104 |
transcriptional regulator KdpE | Two-component system response regulator KdpE. Pfam: Response_reg (PF00072.31), Trans_reg_C (PF00486.35). | Response_reg Trans_reg_C |
Resolved |
| kdpF Rv1028A |
- |
membrane protein KdpF | Membrane protein KdpF. Pfam: Potass_KdpF (PF09604.16). | Potass_KdpF |
Resolved |
| kdpD Rv1028c |
mtbc0_001105 |
sensor protein KdpD | Sensor histidine kinase KdpD. Pfam: KdpD (PF02702.24), Usp (PF00582.33), DUF4118 (PF13493.12), HisKA (PF00512.32), HATPase_c (PF02518.32). | KdpD Usp DUF4118 HisKA HATPase_c |
Resolved |
| kdpA Rv1029 |
mtbc0_001108 |
potassium-transporting ATPase subunit A | Potassium-transporting ATPase subunit KdpA. Pfam: KdpA (PF03814.22). | KdpA |
Family assigned |
| kdpB Rv1030 |
mtbc0_001109 |
potassium-transporting ATPase subunit B | Potassium-transporting ATPase subunit KdpB. Pfam: E1-E2_ATPase (PF00122.26), Hydrolase (PF00702.33). | E1-E2_ATPase Hydrolase |
Family assigned |
| kdpC Rv1031 |
mtbc0_001110 |
potassium-transporting ATPase subunit C | K(+)-transporting ATPase subunit C. Pfam: KdpC (PF02669.21). | KdpC |
Family assigned |
| trcS Rv1032c |
mtbc0_001111 |
two component sensor histidine kinase TrcS | HAMP domain-containing sensor histidine kinase. Pfam: HisKA (PF00512.32), HATPase_c (PF02518.32). | HisKA HATPase_c |
Family assigned |
| trcR Rv1033c |
mtbc0_001112 |
two component transcriptional regulator TrcR | Two-component system response regulator TrcR. Pfam: Response_reg (PF00072.31), Trans_reg_C (PF00486.35). | Response_reg Trans_reg_C |
Resolved |
| esxI Rv1037c |
mtbc0_001114 |
ESAT-6 like protein EsxI | Type VII secretion system ESX-5 protein EsxL. Pfam: WXG100 (PF06013.19). | WXG100 |
Resolved |
| esxJ Rv1038c |
mtbc0_001115 |
ESAT-6 like protein EsxJ | Type VII secretion system ESX-5 protein EsxJ. Pfam: WXG100 (PF06013.19). | WXG100 |
Resolved |
| PPE15 Rv1039c |
- |
PPE family protein PPE15 | PPE family protein PPE15. Pfam: PPE (PF00823.26), PPE-SVP (PF12484.14). | PPE PPE-SVP |
Family assigned |
| PE8 Rv1040c |
- |
PE family protein PE8 | PE family protein PE8. Pfam: PE (PF00934.26), PPE-SVP (PF12484.14). | PE PPE-SVP |
Family assigned |
| Rv1041c Rv1041c |
- |
IS2-like transposase | IS2-like transposase. Pfam: DDE_Tnp_1 (PF01609.28). | DDE_Tnp_1 |
Resolved |
| Rv1042c Rv1042c |
- |
IS2-like transposase | IS2-like transposase. | DUF4096 |
Resolved |
| Rv1043c Rv1043c |
mtbc0_001120 |
hypothetical protein | Serine protease. Pfam: Trypsin (PF00089.33), Trypsin_2 (PF13365.13). | Trypsin Trypsin_2 |
Resolved |
| Rv1044 Rv1044 |
mtbc0_001121 |
hypothetical protein | Type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein. Pfam: AbiEi_4 (PF13338.13). | AbiEi_4 |
Family assigned |
| Rv1045 Rv1045 |
mtbc0_001122 |
hypothetical protein | Nucleotidyl transferase AbiEii/AbiGii toxin family protein. Pfam: AbiEii (PF08843.18). | AbiEii |
Family assigned |
| Rv1047 Rv1047 |
mtbc0_001123 |
transposase | IS256-like element IS1081 family transposase. Pfam: Transposase_mut (PF00872.25). | Transposase_mut |
Family assigned |
| Rv1048c Rv1048c |
mtbc0_001124 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 4rgu-assembly1_A-2 Crystal Structure of Putative MarR Family Transcrip (prob 0.95, TM 0.60). | Still unknown |