Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv3717 Rv3717 |
- |
hypothetical protein | Contains Amidase_3 (PF01520.24) domain(s); putative function inferred from the domain architecture. | Amidase_3 |
Family assigned |
| Rv3718c Rv3718c |
mtbc0_003941 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv3719 Rv3719 |
- |
hypothetical protein | Contains FAD_binding_4 (PF01565.29) domain(s); putative function inferred from the domain architecture. | FAD_binding_4 |
Family assigned |
| Rv3720 Rv3720 |
- |
fatty acid synthase | Fatty acid synthase. Pfam: CMAS (PF02353.27), Methyltransf_23 (PF13489.13), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19). | CMAS Methyltransf_23 Methyltransf_25 Methyltransf_11 |
Resolved |
| dnaZX Rv3721c |
mtbc0_003944 |
DNA polymerase III subunit gamma/tau | DNA polymerase III subunits gamma/tau. Pfam: DNA_pol3_delta2 (PF13177.13), AAA (PF00004.36), AAA_22 (PF13401.13), DNAX_ATPase_lid (PF22608.3), DNA_pol3_gamma3 (PF12169.14). | DNA_pol3_delta2 AAA AAA_22 DNAX_ATPase_lid DNA_pol3_gamma3 |
Family assigned |
| Rv3722c Rv3722c |
mtbc0_003945 |
hypothetical protein | Aminotransferase. Pfam: Asp_aminotransf (PF12897.14). | Asp_aminotransf |
Resolved |
| lucA Rv3723 |
mtbc0_003948 |
transmembrane protein | Lipid uptake coordinator LucA. Pfam: LUCA (PF26307.1). | LUCA |
Resolved |
| Rv3725 Rv3725 |
- |
oxidoreductase | Oxidoreductase. Pfam: NmrA (PF05368.20), RmlD_sub_bind (PF04321.24), Epimerase (PF01370.28), Polysacc_synt_2 (PF02719.22), adh_short (PF00106.32), KR (PF08659.17), 3Beta_HSD (PF01073.26), GDP_Man_Dehyd (PF16363.12), NAD_binding_4 (PF07993.19), NAD_binding_10 (PF13460.13). | NmrA RmlD_sub_bind Epimerase Polysacc_synt_2 adh_short KR 3Beta_HSD GDP_Man_Dehyd NAD_binding_4 NAD_binding_10 |
Resolved |
| Rv3726 Rv3726 |
mtbc0_003951 |
dehydrogenase | Zinc-binding dehydrogenase. Pfam: ADH_N (PF08240.18). | ADH_N |
Resolved |
| Rv3727 Rv3727 |
mtbc0_003952 |
oxidoreductase | FAD-dependent oxidoreductase. Pfam: FAD_binding_3 (PF01494.26), DAO (PF01266.31), FAD_binding_2 (PF00890.31), NAD_binding_8 (PF13450.13), Amino_oxidase (PF01593.31). | FAD_binding_3 DAO FAD_binding_2 NAD_binding_8 Amino_oxidase |
Resolved |
| Rv3728 Rv3728 |
mtbc0_003953 |
membrane protein | MFS transporter. Pfam: Sugar_tr (PF00083.31), MFS_1 (PF07690.22), cNMP_binding (PF00027.36), Patatin (PF01734.28). | Sugar_tr MFS_1 cNMP_binding Patatin |
Resolved |
| Rv3729 Rv3729 |
- |
transferase | Transferase. Pfam: Zn_ribbon_HMPTM (PF23545.2), Radical_SAM (PF04055.28), Fer4_12 (PF13353.12), Methyltransf_23 (PF13489.13), Ubie_methyltran (PF01209.25), Methyltransf_31 (PF13847.13), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19), Methyltransf_12 (PF08242.19). | Zn_ribbon_HMPTM Radical_SAM Fer4_12 Methyltransf_23 Ubie_methyltran Methyltransf_31 Methyltransf_25 Methyltransf_11 Methyltransf_12 |
Resolved |
| ligD Rv3730c |
mtbc0_003955 |
hypothetical protein | Non-homologous end-joining DNA ligase. Pfam: LigD_Prim-Pol (PF21686.4), DNA_primase_S (PF01896.26). | LigD_Prim-Pol DNA_primase_S |
Resolved |
| ligC Rv3731 |
mtbc0_003956 |
DNA ligase C | ATP-dependent DNA ligase. Pfam: DNA_ligase_A_M (PF01068.27), DNA_ligase_A_C (PF04679.22). | DNA_ligase_A_M DNA_ligase_A_C |
Resolved |
| Rv3732 Rv3732 |
mtbc0_003957 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF2330. Function unknown. Foldseek best (non-significant) hit: 6oiu-assembly3_C X-ray crystal structure of the ectodomain of the Toxo (prob 0.14, TM 0.24). | DUF2330 |
Still unknown |
| Rv3733c Rv3733c |
mtbc0_003958 |
hypothetical protein | NUDIX domain-containing protein. Pfam: NUDIX (PF00293.35). | NUDIX |
Family assigned |
| tgs2 Rv3734c |
mtbc0_003959 |
diacyglycerol O-acyltransferase | Wax ester/triacylglycerol synthase family O-acyltransferase. Pfam: WS_DGAT_cat (PF03007.22), WS_DGAT_C (PF06974.19). | WS_DGAT_cat WS_DGAT_C |
Family assigned |
| Rv3735 Rv3735 |
mtbc0_003960 |
hypothetical protein | Adenosine-specific kinase. Pfam: Adenosine_kin (PF04008.20). | Adenosine_kin |
Resolved |
| Rv3736 Rv3736 |
mtbc0_003961 |
AraC/XylS family transcriptional regulator | AraC family transcriptional regulator. Pfam: Arabinose_bd (PF12625.13), HTH_18 (PF12833.14). | Arabinose_bd HTH_18 |
Family assigned |
| Rv3737 Rv3737 |
mtbc0_003962 |
transmembrane protein | Threonine/serine exporter family protein. Pfam: ThrE (PF06738.19), ThrE_2 (PF12821.14). | ThrE ThrE_2 |
Family assigned |
| PPE66 Rv3738c |
- |
PPE family protein PPE66 | PPE family protein PPE66. Pfam: PPE (PF00823.26), PPE-PPW (PF18878.6). | PPE PPE-PPW |
Family assigned |
| PPE67 Rv3739c |
- |
PPE family protein PPE67 | PPE family protein PPE67. Pfam: PPE (PF00823.26). | PPE |
Family assigned |
| Rv3740c Rv3740c |
mtbc0_003964 |
diacyglycerol O-acyltransferase | Wax ester/triacylglycerol synthase family O-acyltransferase. Pfam: WS_DGAT_cat (PF03007.22), WS_DGAT_C (PF06974.19). | WS_DGAT_cat WS_DGAT_C |
Family assigned |
| Rv3741c Rv3741c |
- |
oxidoreductase | Oxidoreductase. | Resolved | |
| Rv3742c Rv3742c |
- |
oxidoreductase | Oxidoreductase. | Resolved | |
| ctpJ Rv3743c |
mtbc0_003966 |
cation transporter ATPase J | Heavy metal translocating P-type ATPase. Pfam: E1-E2_ATPase (PF00122.26), Hydrolase (PF00702.33). | E1-E2_ATPase Hydrolase |
Resolved |
| nmtR Rv3744 |
mtbc0_003967 |
HTH-type transcriptional regulator NmtR | Ni(II)/Co(II)-sensing metalloregulatory transcriptional repressor NmtR. Pfam: HTH_20 (PF12840.14), HTH_5 (PF01022.27), HTH_IclR (PF09339.17), HTH_24 (PF13412.13). | HTH_20 HTH_5 HTH_IclR HTH_24 |
Resolved |
| Rv3745c Rv3745c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF2237. Function unknown. | DUF2237 |
Still unknown |
| PE34 Rv3746c |
- |
PE family protein PE34 | PE family protein PE34. Pfam: PE (PF00934.26). | PE |
Family assigned |
| Rv3747 Rv3747 |
mtbc0_003970 |
hypothetical protein | Conserved hypothetical; function unknown. Structure-based hint rejected: the real Wzm/Wzt galactan-export ABC transporter is Rv3781/Rv3783 (paralogue-of-fold). | Still unknown | |
| Rv3748 Rv3748 |
mtbc0_003971 |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 1qvy-assembly3_C Crystal structure of RhoGDI K(199,200)R double mutant (prob 1.00, TM 0.60). Structure-based, putative. | Family assigned | |
| Rv3749c Rv3749c |
- |
hypothetical protein | Contains VapC50_C (PF26343.1) domain(s); putative function inferred from the domain architecture. | VapC50_C |
Family assigned |
| Rv3750c Rv3750c |
- |
excisionase | Excisionase. Pfam: HTH_17 (PF12728.14). | HTH_17 |
Resolved |
| Rv3752c Rv3752c |
mtbc0_003976 |
cytidine/deoxycytidylate deaminase | Nucleoside deaminase. Pfam: dCMP_cyt_deam_1 (PF00383.30), MafB19-deam (PF14437.13). | dCMP_cyt_deam_1 MafB19-deam |
Resolved |
| Rv3753c Rv3753c |
- |
hypothetical protein | Contains Rv3753c (PF27101.1) domain(s); putative function inferred from the domain architecture. | Rv3753c |
Family assigned |
| tyrA Rv3754 |
- |
prephenate dehydrogenase TyrA | Prephenate dehydrogenase TyrA. Pfam: PDH_N (PF02153.24), PDH_C (PF20463.4). | PDH_N PDH_C |
Resolved |
| Rv3755c Rv3755c |
mtbc0_003979 |
hypothetical protein | Putative glycolipid-binding domain-containing protein. Pfam: Glycolipid_bind (PF06475.19). | Glycolipid_bind |
Family assigned |
| proZ Rv3756c |
mtbc0_003980 |
glycine betaine/carnitine/choline/L-proline ABC transporter permease ProZ | Glycine betaine/carnitine/choline/L-proline ABC transporter permease ProZ. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| proW Rv3757c |
mtbc0_003981 |
glycine betaine/carnitine/choline/L-proline ABC transporter permease ProW | Glycine betaine/carnitine/choline/L-proline ABC transporter permease ProW. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| proV Rv3758c |
mtbc0_003982 |
glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV | Glycine betaine/L-proline ABC transporter ATP-binding protein ProV. Pfam: ABC_tran (PF00005.34). | ABC_tran |
Family assigned |
| proX Rv3759c |
mtbc0_003983 |
glycine betaine/carnitine/choline/L-proline ABC transporter substrate-binding lipoprotein ProX | Glycine betaine/carnitine/choline/L-proline ABC transporter substrate-binding protein ProX. Pfam: OpuAC (PF04069.18). | OpuAC |
Family assigned |
| Rv3760 Rv3760 |
- |
membrane protein | Membrane protein. Pfam: LapA_dom (PF06305.17). | LapA_dom |
Family assigned |
| fadE36 Rv3761c |
mtbc0_003985 |
acyl-CoA dehydrogenase FadE36 | Phosphotransferase family protein. Pfam: APH (PF01636.30). | APH |
Family assigned |
| Rv3762c Rv3762c |
mtbc0_003986 |
hydrolase | Alkyl/aryl-sulfatase. Pfam: Lactamase_B (PF00753.34), Alkyl_sulf_dimr (PF14863.13), Alkyl_sulf_C (PF14864.12). | Lactamase_B Alkyl_sulf_dimr Alkyl_sulf_C |
Resolved |
| lpqH Rv3763 |
mtbc0_003987 |
lipoprotein LpqH | Lipoprotein LpqH. Pfam: Myco_19_kDa (PF05481.18). | Myco_19_kDa |
Resolved |
| tcrY Rv3764c |
- |
two component sensor kinase TcrY | Two component sensor kinase TcrY. Pfam: HAMP (PF00672.31), HisKA (PF00512.32), HATPase_c (PF02518.32). | HAMP HisKA HATPase_c |
Resolved |
| tcrX Rv3765c |
mtbc0_003989 |
two component transcriptional regulator TcrX | Two-component system response regulator TcrX. Pfam: Response_reg (PF00072.31), Trans_reg_C (PF00486.35). | Response_reg Trans_reg_C |
Resolved |
| Rv3766 Rv3766 |
- |
hypothetical protein | Contains Rv3766_C (PF27131.1) domain(s); putative function inferred from the domain architecture. | Rv3766_C |
Family assigned |
| Rv3767c Rv3767c |
mtbc0_003991 |
S-adenosylmethionine-dependent methyltransferase | Class I SAM-dependent methyltransferase. Pfam: LCM (PF04072.21). | LCM |
Resolved |
| Rv3768 Rv3768 |
mtbc0_003992 |
hypothetical protein | Nuclear transport factor 2 family protein. Pfam: SnoaL_2 (PF12680.14). | SnoaL_2 |
Family assigned |