Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv2812 Rv2812 |
mtbc0_002992 |
transposase | Helix-turn-helix domain-containing protein. | Family assigned | |
| Rv2813 Rv2813 |
mtbc0_002993 |
hypothetical protein | ExeA family protein. Pfam: AAA_22 (PF13401.13). | AAA_22 |
Family assigned |
| cas2 Rv2816c |
mtbc0_002994 |
CRISPR-associated endoribonuclease Cas2 | CRISPR-associated endonuclease Cas2. Pfam: CRISPR_Cas2 (PF09827.15). | CRISPR_Cas2 |
Resolved |
| cas1 Rv2817c |
mtbc0_002995 |
CRISPR-associated endonuclease Cas1 | CRISPR-associated endonuclease Cas1. Pfam: Cas_Cas1 (PF01867.22). | Cas_Cas1 |
Resolved |
| Rv2818c Rv2818c |
- |
CRISPR-associated protein Csm6 | CRISPR-associated protein Csm6. Pfam: Cas_Csm6_CARF (PF22208.2), Cas_Csm6_6H (PF22206.3), Cas_Csm6_HEPN (PF09659.17). | Cas_Csm6_CARF Cas_Csm6_6H Cas_Csm6_HEPN |
Resolved |
| csm5 Rv2819c |
mtbc0_002997 |
CRISPR type III-associated RAMP protein Csm5 | Type III-A CRISPR-associated RAMP protein Csm5. Pfam: RAMPs (PF03787.21). | RAMPs |
Resolved |
| csm4 Rv2820c |
mtbc0_002998 |
CRISPR type III-associated RAMP protein Csm4 | Type III-A CRISPR-associated RAMP protein Csm4. Pfam: RAMPs (PF03787.21), Csm4_C (PF17953.7). | RAMPs Csm4_C |
Resolved |
| csm3 Rv2821c |
mtbc0_002999 |
CRISPR type III-associated RAMP protein Csm3 | Type III-A CRISPR-associated RAMP protein Csm3. Pfam: RAMPs (PF03787.21). | RAMPs |
Resolved |
| csm2 Rv2822c |
mtbc0_003000 |
CRISPR type III-associated protein Csm2 | Type III-A CRISPR-associated protein Csm2. Pfam: Csm2_III-A (PF03750.19). | Csm2_III-A |
Resolved |
| cas10 Rv2823c |
mtbc0_003001 |
CRISPR-associated protein Cas10/Csm1 | Type III-A CRISPR-associated protein Cas10/Csm1. Pfam: HD (PF01966.29), Csm1_B (PF18211.8), Cas10-Cmr2_palm2 (PF22335.2), Cmr2_hel_dom2 (PF20824.3). | HD Csm1_B Cas10-Cmr2_palm2 Cmr2_hel_dom2 |
Resolved |
| Rv2824c Rv2824c |
- |
CRISPR-associated endoribonuclease Cas6 | CRISPR-associated endoribonuclease Cas6. Pfam: CRISPR_Cas6 (PF10040.15). | CRISPR_Cas6 |
Resolved |
| Rv2825c Rv2825c |
- |
hypothetical protein | Conserved hypothetical; function unknown. Structure-based hint rejected: structural ASCH hit contradicts the DUF1802 Pfam assignment; function unknown. | DUF1802 |
Still unknown |
| Rv2826c Rv2826c |
mtbc0_003004 |
hypothetical protein | Nucleotidyl transferase AbiEii/AbiGii toxin family protein. Pfam: AbiEii (PF08843.18). | AbiEii |
Family assigned |
| Rv2827c Rv2827c |
mtbc0_003005 |
hypothetical protein | Type IV toxin-antitoxin system AbiEi family antitoxin. Pfam: AbiEi_1 (PF09407.17). | AbiEi_1 |
Family assigned |
| Rv2828A Rv2828A |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF2277. Function unknown. Foldseek best (non-significant) hit: 5wi4-assembly1_C CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH A (prob 0.20, TM 0.63). | DUF2277 |
Still unknown |
| Rv2828c Rv2828c |
mtbc0_003003 |
hypothetical protein | DUF1802 family protein. | DUF1802 |
Family assigned |
| vapC22 Rv2829c |
mtbc0_003008 |
ribonuclease VapC22 | PIN domain-containing protein. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| vapB22 Rv2830c |
mtbc0_003009 |
antitoxin VapB22 | Type II toxin-antitoxin system prevent-host-death family antitoxin. Pfam: PhdYeFM_antitox (PF02604.27). | PhdYeFM_antitox |
Family assigned |
| echA16 Rv2831 |
mtbc0_003010 |
enoyl-CoA hydratase EchA16 | Enoyl-CoA hydratase. Pfam: ECH_1 (PF00378.26), ECH_2 (PF16113.11). | ECH_1 ECH_2 |
Resolved |
| ugpC Rv2832c |
mtbc0_003011 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC | ABC transporter ATP-binding protein. Pfam: ABC_tran (PF00005.34), OB_MalK (PF17912.8). | ABC_tran OB_MalK |
Family assigned |
| ugpB Rv2833c |
mtbc0_003012 |
sn-glycerol-3-phosphate ABC transporter substrate-binding lipoprotein UgpB | ABC transporter substrate-binding protein. Pfam: SBP_bac_1 (PF01547.31), SBP_bac_8 (PF13416.12). | SBP_bac_1 SBP_bac_8 |
Family assigned |
| ugpE Rv2834c |
mtbc0_003013 |
sn-glycerol-3-phosphate ABC transporter permease UgpE | Carbohydrate ABC transporter permease. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| ugpA Rv2835c |
mtbc0_003014 |
sn-glycerol-3-phosphate ABC transporter permease UgpA | Sugar ABC transporter permease. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| dinF Rv2836c |
mtbc0_003015 |
DNA-damage-inducible protein DinF | MATE family efflux transporter. Pfam: MatE (PF01554.24). | MatE |
Family assigned |
| nrnA Rv2837c |
mtbc0_003016 |
bifunctional oligoribonuclease/PAP phosphatase NrnA | Bifunctional oligoribonuclease/PAP phosphatase NrnA. Pfam: DHH (PF01368.28), DHHA1 (PF02272.25). | DHH DHHA1 |
Resolved |
| rbfA Rv2838c |
mtbc0_003017 |
ribosome-binding factor RbfA | 30S ribosome-binding factor RbfA. Pfam: RBFA (PF02033.24). | RBFA |
Resolved |
| infB Rv2839c |
mtbc0_003018 |
translation initiation factor IF-2 | Translation initiation factor IF-2. Pfam: IF2_N (PF04760.22), GTP_EFTU (PF00009.34), MMR_HSR1 (PF01926.30), Ras (PF00071.29), EF-G_D2 (PF22042.3), IF-2 (PF11987.14). | IF2_N GTP_EFTU MMR_HSR1 Ras EF-G_D2 IF-2 |
Resolved |
| Rv2840c Rv2840c |
- |
hypothetical protein | Contains YlxR (PF04296.19) domain(s); putative function inferred from the domain architecture. | YlxR |
Family assigned |
| nusA Rv2841c |
mtbc0_003020 |
transcription termination/antitermination protein NusA | Transcription termination factor NusA. Pfam: NusA_N (PF08529.17), KH_NusA_1st (PF13184.13), KH_NusA_2nd (PF26594.2). | NusA_N KH_NusA_1st KH_NusA_2nd |
Resolved |
| rimP Rv2842c |
mtbc0_003021 |
ribosome maturation factor RimP | Ribosome maturation factor RimP. Pfam: RimP_N (PF02576.23), DUF150_C (PF17384.9). | RimP_N DUF150_C |
Resolved |
| Rv2843 Rv2843 |
mtbc0_003022 |
hypothetical protein | Small membrane protein under strong purifying selection (pN/pS 0). Its fold weakly resembles actinobacterial respiratory-supercomplex accessory subunits (HHpred 7Q21_l, E~1.8, near the TM-helix promiscuity floor). Function undetermined; the supercomplex association is a weak, uncorroborated structural hint. | Family assigned | |
| Rv2844 Rv2844 |
mtbc0_003023 |
hypothetical protein | Ferritin-like domain-containing protein. | DUF4439 |
Family assigned |
| proS Rv2845c |
mtbc0_003024 |
proline--tRNA ligase | Proline--tRNA ligase. Pfam: tRNA-synt_2b (PF00587.31), tRNA_edit (PF04073.21), HGTP_anticodon (PF03129.26). | tRNA-synt_2b tRNA_edit HGTP_anticodon |
Resolved |
| efpA Rv2846c |
mtbc0_003025 |
MFS-type transporter EfpA | Multidrug efflux MFS transporter EfpA. Pfam: MFS_1 (PF07690.22). | MFS_1 |
Resolved |
| cysG Rv2847c |
mtbc0_003026 |
multifunctional uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase | Uroporphyrinogen-III C-methyltransferase. Pfam: NAD_binding_7 (PF13241.13), TP_methylase (PF00590.26). | NAD_binding_7 TP_methylase |
Resolved |
| cobB Rv2848c |
mtbc0_003027 |
cobyrinic acid A,C-diamide synthase | Cobyrinate a%2Cc-diamide synthase. Pfam: CbiA (PF01656.30), AAA_26 (PF13500.13), GATase_3 (PF07685.21). | CbiA AAA_26 GATase_3 |
Resolved |
| cobO Rv2849c |
- |
cob(I)alamin adenosyltransferase | Cob(I)alamin adenosyltransferase. Pfam: CobA_CobO_BtuR (PF02572.22). | CobA_CobO_BtuR |
Resolved |
| Rv2850c Rv2850c |
mtbc0_003029 |
magnesium chelatase | Magnesium chelatase subunit D family protein. Pfam: AAA_5 (PF07728.21), MCM (PF00493.30), Mg_chelatase (PF01078.28), AAA_lid_2 (PF17863.8), VWA_2 (PF13519.13), VWA (PF00092.35). | AAA_5 MCM Mg_chelatase AAA_lid_2 VWA_2 VWA |
Family assigned |
| Rv2851c Rv2851c |
mtbc0_003030 |
GCN5-like N-acetyltransferase | GNAT family N-acetyltransferase. Pfam: Acetyltransf_10 (PF13673.14). | Acetyltransf_10 |
Family assigned |
| mqo Rv2852c |
mtbc0_003031 |
malate:quinone oxidoreductase | Malate dehydrogenase (quinone). Pfam: Mqo (PF06039.22), DAO (PF01266.31). | Mqo DAO |
Resolved |
| PE_PGRS48 Rv2853 |
- |
PE-PGRS family protein PE_PGRS48 | PE-PGRS family protein PE_PGRS48. Pfam: PE (PF00934.26), PGRS (PF21526.3). | PE PGRS |
Family assigned |
| Rv2854 Rv2854 |
mtbc0_003033 |
hypothetical protein | Alpha/beta hydrolase. Pfam: Hydrolase_4 (PF12146.16), Abhydrolase_1 (PF00561.27), Abhydrolase_6 (PF12697.14). | Hydrolase_4 Abhydrolase_1 Abhydrolase_6 |
Family assigned |
| mtr Rv2855 |
- |
mycothione reductase | Mycothione reductase. Pfam: Pyr_redox_2 (PF07992.21), Pyr_redox_3 (PF13738.13), Lys_Orn_oxgnase (PF13434.13), Pyr_redox (PF00070.34), Pyr_redox_dim (PF02852.29). | Pyr_redox_2 Pyr_redox_3 Lys_Orn_oxgnase Pyr_redox Pyr_redox_dim |
Resolved |
| nicT Rv2856 |
mtbc0_003035 |
nickel-transport integral membrane protein NicT | HoxN/HupN/NixA family nickel/cobalt transporter. Pfam: NicO (PF03824.23). | NicO |
Family assigned |
| Rv2857c Rv2857c |
mtbc0_003038 |
3-oxoacyl-ACP reductase | 3-oxoacyl-ACP reductase. Pfam: adh_short (PF00106.32), adh_short_C2 (PF13561.13). | adh_short adh_short_C2 |
Resolved |
| aldC Rv2858c |
- |
aldehyde dehydrogenase AldC | Aldehyde dehydrogenase AldC. Pfam: Aldedh (PF00171.28). | Aldedh |
Resolved |
| Rv2859c Rv2859c |
mtbc0_003040 |
glutamine amidotransferase | Gamma-glutamyl-gamma-aminobutyrate hydrolase. Pfam: Peptidase_C26 (PF07722.20), GATase (PF00117.35). | Peptidase_C26 GATase |
Resolved |
| glnA4 Rv2860c |
mtbc0_003041 |
glutamine synthetase | Glutamine synthetase family protein. Pfam: Gln-synt_C (PF00120.30). | Gln-synt_C |
Family assigned |
| mapB Rv2861c |
- |
methionine aminopeptidase | Methionine aminopeptidase. Pfam: Peptidase_M24 (PF00557.30). | Peptidase_M24 |
Resolved |
| vapB23 Rv2862A |
- |
antitoxin VapB23 | Antitoxin VapB23. | Resolved |