Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| cut3 Rv3451 |
mtbc0_003670 |
cutinase | Cutinase family protein. Pfam: Cutinase (PF01083.29). | Cutinase |
Family assigned |
| cut4 Rv3452 |
mtbc0_003671 |
cutinase | Cutinase Cut4. Pfam: Cutinase (PF01083.29). | Cutinase |
Resolved |
| Rv3453 Rv3453 |
|
Possible conserved transmembrane protein | Possible conserved transmembrane protein | Family assigned | |
| Rv3454 Rv3454 |
|
Probable conserved integral membrane protein | Probable conserved integral membrane protein | Family assigned | |
| truA Rv3455c |
- |
tRNA pseudouridine synthase A | TRNA pseudouridine synthase A. Pfam: PseudoU_synth_1 (PF01416.26). | PseudoU_synth_1 |
Resolved |
| rplQ Rv3456c |
mtbc0_003674 |
50S ribosomal protein L17 | 50S ribosomal protein L17. Pfam: Ribosomal_L17 (PF01196.25). | Ribosomal_L17 |
Resolved |
| rpoA Rv3457c |
mtbc0_003675 |
DNA-directed RNA polymerase subunit alpha | DNA-directed RNA polymerase subunit alpha. Pfam: RNA_pol_L (PF01193.30), RNA_pol_A_bac (PF01000.32), RNA_pol_A_CTD (PF03118.22). | RNA_pol_L RNA_pol_A_bac RNA_pol_A_CTD |
Family assigned |
| rpsD Rv3458c |
mtbc0_003676 |
30S ribosomal protein S4 | 30S ribosomal protein S4. Pfam: Ribosomal_S4 (PF00163.25), S4 (PF01479.31). | Ribosomal_S4 S4 |
Resolved |
| rpsK Rv3459c |
mtbc0_003677 |
30S ribosomal protein S11 | 30S ribosomal protein S11. Pfam: Ribosomal_S11 (PF00411.25). | Ribosomal_S11 |
Resolved |
| rpsM Rv3460c |
mtbc0_003678 |
30S ribosomal protein S13 | 30S ribosomal protein S13. Pfam: Ribosomal_S13 (PF00416.28). | Ribosomal_S13 |
Resolved |
| rpmJ Rv3461c |
mtbc0_003679 |
50S ribosomal protein L36 | 50S ribosomal protein L36. Pfam: Ribosomal_L36 (PF00444.24). | Ribosomal_L36 |
Resolved |
| infA Rv3462c |
- |
translation initiation factor IF-1 | Translation initiation factor IF-1. Pfam: eIF-1a (PF01176.26). | eIF-1a |
Resolved |
| Rv3463 Rv3463 |
mtbc0_003681 |
hypothetical protein | LLM class F420-dependent oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Resolved |
| rmlB Rv3464 |
mtbc0_003682 |
dTDP-glucose 4,6-dehydratase | DTDP-glucose 4%2C6-dehydratase. Pfam: RmlD_sub_bind (PF04321.24), Polysacc_synt_2 (PF02719.22), GDP_Man_Dehyd (PF16363.12), Epimerase (PF01370.28), 3Beta_HSD (PF01073.26), NAD_binding_4 (PF07993.19), NAD_binding_10 (PF13460.13). | RmlD_sub_bind Polysacc_synt_2 GDP_Man_Dehyd Epimerase 3Beta_HSD NAD_binding_4 NAD_binding_10 |
Resolved |
| rmlC Rv3465 |
mtbc0_003683 |
dTDP-4-dehydrorhamnose 3,5-epimerase | DTDP-4-dehydrorhamnose 3%2C5-epimerase. Pfam: dTDP_sugar_isom (PF00908.24). | dTDP_sugar_isom |
Resolved |
| Rv3466 Rv3466 |
- |
hypothetical protein | HNH-family endonuclease of the 13E12-repeat family (eggNOG COG1403, COG category V). HNH nuclease motif; target undetermined. | DUF222 |
Family assigned |
| Rv3467 Rv3467 |
- |
hypothetical protein | HNH-family endonuclease of the 13E12-repeat family (eggNOG COG1403, COG category V). HNH nuclease motif; target undetermined. | DUF222 |
Family assigned |
| Rv3468c Rv3468c |
- |
dTDP-glucose 4,6-dehydratase | DTDP-glucose 4,6-dehydratase. Pfam: RmlD_sub_bind (PF04321.24), Epimerase (PF01370.28), 3Beta_HSD (PF01073.26), GDP_Man_Dehyd (PF16363.12), NAD_binding_10 (PF13460.13), Polysacc_synt_2 (PF02719.22), NAD_binding_4 (PF07993.19). | RmlD_sub_bind Epimerase 3Beta_HSD GDP_Man_Dehyd NAD_binding_10 Polysacc_synt_2 NAD_binding_4 |
Resolved |
| mhpE Rv3469c |
mtbc0_003686 |
4-hydroxy-2-oxovalerate aldolase MhpE | 4-hydroxy-2-oxovalerate aldolase. Pfam: HMGL-like (PF00682.26). | HMGL-like |
Resolved |
| ilvB2 Rv3470c |
mtbc0_003687 |
acetolactate synthase large subunit | Thiamine pyrophosphate-binding protein. Pfam: TPP_enzyme_N (PF02776.24), TPP_enzyme_M (PF00205.29), TPP_enzyme_C (PF02775.27). | TPP_enzyme_N TPP_enzyme_M TPP_enzyme_C |
Family assigned |
| Rv3471c Rv3471c |
- |
hypothetical protein | Contains Cupin_2 (PF07883.18) domain(s); putative function inferred from the domain architecture. | Cupin_2 |
Family assigned |
| Rv3472 Rv3472 |
mtbc0_003689 |
hypothetical protein | Nuclear transport factor 2 family protein. Pfam: SnoaL_4 (PF13577.13), DUF4440 (PF14534.13). | SnoaL_4 DUF4440 |
Family assigned |
| bpoA Rv3473c |
- |
peroxidase BpoA | Peroxidase BpoA. Pfam: Abhydrolase_1 (PF00561.27), Abhydrolase_6 (PF12697.14), Hydrolase_4 (PF12146.16). | Abhydrolase_1 Abhydrolase_6 Hydrolase_4 |
Resolved |
| kgtP Rv3476c |
|
Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) | Involved in active transport of dicarboxylic acid across the membrane. Responsible for the translocation of the substrate across the membrane. | Sugar_tr |
Family assigned |
| PE31 Rv3477 |
- |
PE family protein PE31 | PE family protein PE31. Pfam: PE (PF00934.26). | PE |
Family assigned |
| PPE60 Rv3478 |
- |
PE family protein PPE60 | PE family protein PPE60. Pfam: PPE (PF00823.26), PPE-SVP (PF12484.14). | PPE PPE-SVP |
Family assigned |
| Rv3479 Rv3479 |
- |
transmembrane protein | Transmembrane protein. Pfam: Patatin (PF01734.28), DUF3376 (PF11856.14). | Patatin DUF3376 |
Resolved |
| Rv3480c Rv3480c |
mtbc0_003695 |
diacyglycerol O-acyltransferase | Wax ester/triacylglycerol synthase family O-acyltransferase. Pfam: WS_DGAT_cat (PF03007.22), WS_DGAT_C (PF06974.19). | WS_DGAT_cat WS_DGAT_C |
Family assigned |
| Rv3481c Rv3481c |
mtbc0_003696 |
integral membrane protein | GAP family protein. Pfam: SfLAP (PF11139.15). | SfLAP |
Family assigned |
| Rv3482c Rv3482c |
mtbc0_003697 |
membrane protein | Conserved hypothetical protein; DUF domain(s) DUF2510. Function unknown. | DUF2510 |
Still unknown |
| Rv3483c Rv3483c |
mtbc0_003698 |
hypothetical protein | LppP/LprE family lipoprotein. Pfam: Lipoprotein_21 (PF14041.12). | Lipoprotein_21 |
Family assigned |
| cpsA Rv3484 |
mtbc0_003699 |
hypothetical protein | LCP family protein. Pfam: LytR_cpsA_psr (PF03816.20), LytR_C (PF13399.12). | LytR_cpsA_psr LytR_C |
Family assigned |
| Rv3485c Rv3485c |
- |
short-chain type dehydrogenase/reductase | Short-chain type dehydrogenase/reductase. Pfam: SDR (PF23441.1), KR (PF08659.17), adh_short (PF00106.32), Epimerase (PF01370.28), adh_short_C2 (PF13561.13). | SDR KR adh_short Epimerase adh_short_C2 |
Resolved |
| Rv3486 Rv3486 |
mtbc0_003701 |
hypothetical protein | DoxX family protein. Pfam: DoxX (PF07681.18). | DoxX |
Family assigned |
| lipF Rv3487c |
- |
carboxylesterase LipF | Carboxylesterase LipF. Pfam: BD-FAE (PF20434.6), Say1_Mug180 (PF10340.16), Abhydrolase_3 (PF07859.20). | BD-FAE Say1_Mug180 Abhydrolase_3 |
Resolved |
| Rv3488 Rv3488 |
mtbc0_003703 |
hypothetical protein | PadR family transcriptional regulator. Pfam: PadR (PF03551.21). | PadR |
Family assigned |
| Rv3489 Rv3489 |
mtbc0_003704 |
hypothetical protein | Conserved protein co-transcribed with otsA (trehalose-6-phosphate synthase) under purifying selection. Contextual candidate: associated with trehalose biosynthesis / metabolism. Its molecular role is not established. | Family assigned | |
| otsA Rv3490 |
mtbc0_003705 |
trehalose-phosphate synthase | Trehalose-6-phosphate synthase. Pfam: Glyco_transf_20 (PF00982.28). | Glyco_transf_20 |
Resolved |
| Rv3491 Rv3491 |
mtbc0_003706 |
hypothetical protein | Membrane-anchored protein with a PknI-sensor-domain-like extracytoplasmic sensor fold; distinct from PknI/Rv2914c (fold-paralogue safeguard); ligand/partner undetermined RefSeq leaves this locus uncharacterised. | Family assigned | |
| Rv3492c Rv3492c |
mtbc0_003707 |
Mce associated protein | Mce associated protein. | Resolved | |
| Rv3493c Rv3493c |
mtbc0_003708 |
Mce associated protein | Mammalian cell entry protein. | Resolved | |
| mce4F Rv3494c |
mtbc0_003709 |
Mce family protein Mce4 | Virulence factor Mce family protein. Pfam: MlaD (PF02470.26). | MlaD |
Family assigned |
| lprN Rv3495c |
mtbc0_003710 |
Mce family lipoprotein LprN | Mce family lipoprotein LprN. Pfam: MlaD (PF02470.26). | MlaD |
Family assigned |
| mce4D Rv3496c |
mtbc0_003711 |
Mce family protein Mce4D | Virulence factor Mce family protein. Pfam: MlaD (PF02470.26), Mce4_CUP1 (PF11887.14). | MlaD Mce4_CUP1 |
Family assigned |
| mce4C Rv3497c |
mtbc0_003712 |
Mce family protein Mce4C | Virulence factor Mce family protein. Pfam: MlaD (PF02470.26), Mce4_CUP1 (PF11887.14). | MlaD Mce4_CUP1 |
Family assigned |
| mce4B Rv3498c |
mtbc0_003713 |
Mce family protein Mce4B | Virulence factor Mce family protein. Pfam: MlaD (PF02470.26), Mce4_CUP1 (PF11887.14). | MlaD Mce4_CUP1 |
Family assigned |
| mce4A Rv3499c |
- |
Mce family protein Mce4A | Mce family protein Mce4A. Pfam: MlaD (PF02470.26), Mce4_CUP1 (PF11887.14). | MlaD Mce4_CUP1 |
Family assigned |
| yrbE4B Rv3500c |
mtbc0_003715 |
integral membrane protein | ABC transporter permease. Pfam: MlaE (PF02405.22). | MlaE |
Family assigned |
| yrbE4A Rv3501c |
mtbc0_003716 |
integral membrane protein | ABC transporter permease. Pfam: MlaE (PF02405.22). | MlaE |
Family assigned |
| Rv3502c Rv3502c |
mtbc0_003717 |
3-oxoacyl-ACP reductase | 3-oxoacyl-ACP reductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Resolved |