Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| PE_PGRS30 Rv1651c |
- |
PE-PGRS family protein PE_PGRS30 | PE-PGRS family protein PE_PGRS30. Pfam: PE (PF00934.26). | PE |
Family assigned |
| argC Rv1652 |
mtbc0_001761 |
N-acetyl-gamma-glutamyl-phoshate reductase | N-acetyl-gamma-glutamyl-phosphate reductase. Pfam: Semialdhyde_dh (PF01118.31), Semialdhyde_dhC_1 (PF22698.2), Semialdhyde_dhC (PF02774.24). | Semialdhyde_dh Semialdhyde_dhC_1 Semialdhyde_dhC |
Resolved |
| argJ Rv1653 |
mtbc0_001762 |
bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase | Bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ. Pfam: ArgJ (PF01960.24). | ArgJ |
Resolved |
| argB Rv1654 |
mtbc0_001763 |
acetylglutamate kinase | Acetylglutamate kinase. Pfam: AA_kinase (PF00696.34). | AA_kinase |
Resolved |
| argD Rv1655 |
mtbc0_001764 |
acetylornithine aminotransferase | Acetylornithine transaminase. Pfam: Aminotran_3 (PF00202.28), Aminotran_1_2 (PF00155.28). | Aminotran_3 Aminotran_1_2 |
Resolved |
| argF Rv1656 |
mtbc0_001765 |
ornithine carbamoyltransferase | Ornithine carbamoyltransferase. Pfam: OTCace_N (PF02729.27), OTCace (PF00185.31). | OTCace_N OTCace |
Resolved |
| argR Rv1657 |
mtbc0_001766 |
arginine repressor | Arginine repressor. Pfam: Arg_repressor (PF01316.28), Arg_repressor_C (PF02863.24). | Arg_repressor Arg_repressor_C |
Resolved |
| argG Rv1658 |
mtbc0_001767 |
argininosuccinate synthase | Argininosuccinate synthase. Pfam: Arginosuc_synth (PF00764.26), Arginosuc_syn_C (PF20979.3). | Arginosuc_synth Arginosuc_syn_C |
Resolved |
| argH Rv1659 |
mtbc0_001768 |
argininosuccinate lyase | Argininosuccinate lyase. Pfam: Lyase_1 (PF00206.26), ASL_C2 (PF14698.12). | Lyase_1 ASL_C2 |
Resolved |
| pks10 Rv1660 |
mtbc0_001769 |
chalcone synthase | Type III polyketide synthase. Pfam: Chal_sti_synt_N (PF00195.26), FAE1_CUT1_RppA (PF08392.19), Chal_sti_synt_C (PF02797.22), ACP_syn_III_C (PF08541.17). | Chal_sti_synt_N FAE1_CUT1_RppA Chal_sti_synt_C ACP_syn_III_C |
Resolved |
| pks7 Rv1661 |
mtbc0_001770 |
polyketide synthase | Type I polyketide synthase. Pfam: Docking (PF08990.17), ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), CurL-like_PKS_C (PF22621.3), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), SpnB_Rossmann (PF22953.4), ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13), KR (PF08659.17), adh_short (PF00106.32), Epimerase (PF01370.28), PP-binding (PF00550.32). | Docking ketoacyl-synt Ketoacyl-synt_C KAsynt_C_assoc CurL-like_PKS_C Acyl_transf_1 PKS_DH_N PS-DH SpnB_Rossmann ADH_N ADH_zinc_N ADH_zinc_N_2 KR adh_short Epimerase PP-binding |
Resolved |
| pks8 Rv1662 |
- |
polyketide synthase | Polyketide synthase. Pfam: Docking (PF08990.17), ketoacyl-synt (PF00109.33), Thiolase_N (PF00108.30), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), CurL-like_PKS_C (PF22621.3), RhiE-like_linker (PF22336.3), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), SpnB_Rossmann (PF22953.4), ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13). | Docking ketoacyl-synt Thiolase_N Ketoacyl-synt_C KAsynt_C_assoc CurL-like_PKS_C RhiE-like_linker Acyl_transf_1 PKS_DH_N PS-DH SpnB_Rossmann ADH_N ADH_zinc_N ADH_zinc_N_2 |
Resolved |
| pks17 Rv1663 |
- |
polyketide synthase | Polyketide synthase. Pfam: KR (PF08659.17), adh_short (PF00106.32), Epimerase (PF01370.28), Polysacc_synt_2 (PF02719.22), GDP_Man_Dehyd (PF16363.12), 3Beta_HSD (PF01073.26), adh_short_C2 (PF13561.13), PP-binding (PF00550.32). | KR adh_short Epimerase Polysacc_synt_2 GDP_Man_Dehyd 3Beta_HSD adh_short_C2 PP-binding |
Resolved |
| pks9 Rv1664 |
mtbc0_001772 |
polyketide synthase | Type I polyketide synthase. Pfam: ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), CurL-like_PKS_C (PF22621.3), Acyl_transf_1 (PF00698.27), PP-binding (PF00550.32). | ketoacyl-synt Ketoacyl-synt_C KAsynt_C_assoc CurL-like_PKS_C Acyl_transf_1 PP-binding |
Resolved |
| pks11 Rv1665 |
mtbc0_001773 |
chalcone synthase | Type III polyketide synthase. Pfam: Chal_sti_synt_N (PF00195.26), FAE1_CUT1_RppA (PF08392.19), Chal_sti_synt_C (PF02797.22), ACP_syn_III_C (PF08541.17). | Chal_sti_synt_N FAE1_CUT1_RppA Chal_sti_synt_C ACP_syn_III_C |
Resolved |
| cyp139 Rv1666c |
mtbc0_001774 |
cytochrome P450 Cyp139 | Cytochrome P450. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| Rv1669 Rv1669 |
mtbc0_001776 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3jsy-assembly2_B N-terminal fragment of ribosomal protein L10 from Met (prob 0.10, TM 0.55). | Still unknown | |
| Rv1670 Rv1670 |
mtbc0_001777 |
hypothetical protein | DUF427 domain-containing protein. Pfam: NTP_transf_9 (PF04248.20). | NTP_transf_9 |
Family assigned |
| Rv1671 Rv1671 |
mtbc0_001778 |
membrane protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1672c Rv1672c |
mtbc0_001779 |
integral membrane transport protein | MFS transporter. Pfam: MFS_1 (PF07690.22). | MFS_1 |
Resolved |
| Rv1673c Rv1673c |
mtbc0_001780 |
hypothetical protein | Transglutaminase family protein. Pfam: Transglut_core (PF01841.26). | Transglut_core |
Family assigned |
| Rv1674c Rv1674c |
mtbc0_001781 |
transcriptional regulator | Metalloregulator ArsR/SmtB family transcription factor. Pfam: HTH_20 (PF12840.14), HTH_5 (PF01022.27), Rhodanese (PF00581.26). | HTH_20 HTH_5 Rhodanese |
Family assigned |
| cmr Rv1675c |
mtbc0_001783 |
HTH-type transcriptional regulator Cmr | HTH-type transcriptional regulator Cmr. Pfam: cNMP_binding (PF00027.36), HTH_Crp_2 (PF13545.13). | cNMP_binding HTH_Crp_2 |
Family assigned |
| Rv1676 Rv1676 |
mtbc0_001784 |
hypothetical protein | Peroxiredoxin-like family protein. Pfam: AhpC-TSA (PF00578.28), AhpC-TSA_2 (PF13911.13). | AhpC-TSA AhpC-TSA_2 |
Family assigned |
| dsbF Rv1677 |
mtbc0_001785 |
lipoprotein DsbF | Protein disulfide oxidoreductase. Pfam: Redoxin (PF08534.17), AhpC-TSA (PF00578.28), Thioredoxin_2 (PF13098.14), Thioredoxin (PF00085.27). | Redoxin AhpC-TSA Thioredoxin_2 Thioredoxin |
Resolved |
| Rv1678 Rv1678 |
mtbc0_001786 |
integral membrane protein | Polytopic integral membrane protein with a GT-C-like / membrane-enzyme-chaperone fold; weakly linked to M.tb Emb arabinosyltransferases (cell-wall GT-C family); specific function undetermined RefSeq leaves this locus uncharacterised. | Family assigned | |
| fadE16 Rv1679 |
mtbc0_001787 |
acyl-CoA dehydrogenase FadE16 | Acyl-CoA dehydrogenase family protein. Pfam: Acyl-CoA_dh_N (PF02771.22), Acyl-CoA_dh_M (PF02770.25), Acyl-CoA_dh_1 (PF00441.30), Acyl-CoA_dh_2 (PF08028.17). | Acyl-CoA_dh_N Acyl-CoA_dh_M Acyl-CoA_dh_1 Acyl-CoA_dh_2 |
Family assigned |
| Rv1680 Rv1680 |
mtbc0_001788 |
hypothetical protein | Phosphate/phosphite/phosphonate ABC transporter substrate-binding protein. Pfam: Phosphonate-bd (PF12974.13). | Phosphonate-bd |
Family assigned |
| moeX Rv1681 |
mtbc0_001789 |
molybdopterin biosynthesis protein MoeX | Radical SAM protein. Pfam: Fer4_12 (PF13353.12), Radical_SAM (PF04055.28). | Fer4_12 Radical_SAM |
Resolved |
| Rv1682 Rv1682 |
- |
hypothetical protein | SMC-like coiled-coil ATPase of the chromosome-segregation / structural-maintenance family (eggNOG COG1196), in an RD (DS6) context. Coiled-coil ATPase fold; precise role undetermined. | Family assigned | |
| Rv1683 Rv1683 |
mtbc0_001791 |
bifunctional long-chain acyl-CoA synthase/lipase | Acyl-CoA synthetase. Pfam: Abhydrolase_1 (PF00561.27), AMP-binding (PF00501.35). | Abhydrolase_1 AMP-binding |
Resolved |
| Rv1684 Rv1684 |
mtbc0_001792 |
hypothetical protein | Trm112 family protein. Pfam: Trm112p (PF03966.23). | Trm112p |
Family assigned |
| Rv1685c Rv1685c |
mtbc0_001793 |
hypothetical protein | TetR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_16 (PF17920.7). | TetR_N TetR_C_16 |
Family assigned |
| Rv1686c Rv1686c |
- |
ABC transporter permease | ABC transporter permease. Pfam: ABC2_membrane (PF01061.30), ABC2_membrane_3 (PF12698.14), ABC2_membrane_2 (PF12679.14). | ABC2_membrane ABC2_membrane_3 ABC2_membrane_2 |
Family assigned |
| Rv1687c Rv1687c |
mtbc0_001795 |
ABC transporter ATP-binding protein | ABC transporter ATP-binding protein. Pfam: ABC_tran (PF00005.34), AAA_21 (PF13304.13). | ABC_tran AAA_21 |
Family assigned |
| mpg Rv1688 |
mtbc0_001796 |
3-methyladenine DNA glycosylase | DNA-3-methyladenine glycosylase. Pfam: Pur_DNA_glyco (PF02245.22). | Pur_DNA_glyco |
Resolved |
| tyrS Rv1689 |
mtbc0_001797 |
tyrosine--tRNA ligase | Tyrosine--tRNA ligase. Pfam: tRNA-synt_1b (PF00579.32), SYY_C-terminal (PF22421.2). | tRNA-synt_1b SYY_C-terminal |
Resolved |
| lprJ Rv1690 |
mtbc0_001798 |
lipoprotein LprJ | Lipoprotein LprJ. | DUF732 |
Resolved |
| Rv1691 Rv1691 |
mtbc0_001799 |
hypothetical protein | TPR-repeat fold (PDB 2PL2); putative protein-protein-interaction scaffold. | Family assigned | |
| Rv1692 Rv1692 |
mtbc0_001800 |
phosphatase | HAD-IIA family hydrolase. Pfam: Hydrolase (PF00702.33), Hydrolase_6 (PF13344.13), Hydrolase_like (PF13242.13), GNAT_like (PF18407.8). | Hydrolase Hydrolase_6 Hydrolase_like GNAT_like |
Family assigned |
| Rv1693 Rv1693 |
mtbc0_001801 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3dxr-assembly1_B Crystal structure of the yeast inter-membrane space c (prob 0.44, TM 0.55). | Still unknown | |
| tlyA Rv1694 |
mtbc0_001802 |
16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA | 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA. Pfam: S4 (PF01479.31), FtsJ (PF01728.26). | S4 FtsJ |
Resolved |
| ppnK Rv1695 |
mtbc0_001803 |
inorganic polyphosphate/ATP-NAD kinase | NAD kinase. Pfam: NAD_kinase (PF01513.27), NAD_kinase_C (PF20143.5). | NAD_kinase NAD_kinase_C |
Resolved |
| recN Rv1696 |
mtbc0_001804 |
DNA repair protein RecN | DNA repair protein RecN. Pfam: SMC_N (PF02463.26). | SMC_N |
Resolved |
| steA Rv1697 |
mtbc0_001805 |
hypothetical protein | Putative cytokinetic ring protein SteA. Pfam: SteA-like_C (PF12555.14). | SteA-like_C |
Family assigned |
| mctB Rv1698 |
mtbc0_001806 |
copper transporter MctB | Copper transporter MctB. Pfam: MctB (PF11382.14). | MctB |
Resolved |
| pyrG Rv1699 |
mtbc0_001807 |
CTP synthase | CTP synthase. Pfam: CTP_synth_N (PF06418.21), GATase (PF00117.35), Peptidase_C26 (PF07722.20). | CTP_synth_N GATase Peptidase_C26 |
Resolved |
| Rv1700 Rv1700 |
mtbc0_001808 |
NUDIX hydrolase | ADP-ribose diphosphatase. Pfam: NDPSase_N (PF28549.1), NUDIX (PF00293.35). | NDPSase_N NUDIX |
Resolved |
| xerD Rv1701 |
mtbc0_001809 |
tyrosine recombinase XerD | Site-specific tyrosine recombinase XerD. Pfam: Phage_int_SAM_1 (PF02899.24), Phage_integrase (PF00589.28). | Phage_int_SAM_1 Phage_integrase |
Resolved |
| Rv1702c Rv1702c |
mtbc0_001810 |
hypothetical protein | HNH endonuclease signature motif containing protein. | DUF222 |
Resolved |