Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| lppC Rv1911c |
mtbc0_002026 |
lipoprotein LppC | YbhB/YbcL family Raf kinase inhibitor-like protein. Pfam: PBP (PF01161.26). | PBP |
Family assigned |
| fadB5 Rv1912c |
mtbc0_002027 |
oxidoreductase FadB | Medium chain dehydrogenase/reductase family protein. Pfam: ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13). | ADH_N ADH_zinc_N ADH_zinc_N_2 |
Family assigned |
| Rv1913 Rv1913 |
mtbc0_002028 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B (PF00753.34). | Lactamase_B |
Resolved |
| Rv1914c Rv1914c |
mtbc0_002029 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 2ys5-assembly1_A Solution structure of the complex of the PTB domain o (prob 0.38, TM 0.51). | Still unknown | |
| aceAa Rv1915 |
- |
isocitrate lyase AceAa | Isocitrate lyase AceAa. Pfam: ICL (PF00463.28), PEP_mutase (PF13714.13). | ICL PEP_mutase |
Resolved |
| aceAb Rv1916 |
- |
isocitrate lyase AceAb | Isocitrate lyase AceAb. Pfam: ICL (PF00463.28). | ICL |
Resolved |
| PPE34 Rv1917c |
- |
PPE family protein PPE34 | PPE family protein PPE34. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| PPE35 Rv1918c |
- |
PPE family protein PPE35 | PPE family protein PPE35. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| Rv1919c Rv1919c |
mtbc0_002033 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv1920 Rv1920 |
mtbc0_002034 |
membrane protein | Lysophospholipid acyltransferase family protein. Pfam: Acyltransferase (PF01553.27), DAGAT (PF03982.19). | Acyltransferase DAGAT |
Family assigned |
| lppF Rv1921c |
mtbc0_002035 |
lipoprotein LppF | Haloacid dehalogenase-like hydrolase. Pfam: Hydrolase (PF00702.33), HAD (PF12710.14). | Hydrolase HAD |
Resolved |
| Rv1922 Rv1922 |
mtbc0_002036 |
lipoprotein | Serine hydrolase. Pfam: Beta-lactamase (PF00144.30). | Beta-lactamase |
Resolved |
| lipD Rv1923 |
- |
lipase LipD | Lipase LipD. Pfam: Beta-lactamase (PF00144.30). | Beta-lactamase |
Resolved |
| Rv1924c Rv1924c |
mtbc0_002038 |
hypothetical protein | Polytopic integral membrane protein with 3 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | Family assigned | |
| fadD31 Rv1925 |
mtbc0_002039 |
fatty-acid--CoA ligase FadD31 | Fatty-acid--AMP ligase FAAL31/FadD31. Pfam: AMP-binding (PF00501.35). | AMP-binding |
Resolved |
| mpt63 Rv1926c |
mtbc0_002040 |
immunogenic protein Mpt63 | Immunoprotective protein Mpt63. | DUF1942 |
Resolved |
| Rv1927 Rv1927 |
mtbc0_002041 |
hypothetical protein | YqjF family protein. | DUF2071 |
Family assigned |
| Rv1928c Rv1928c |
mtbc0_002042 |
short-chain type dehydrogenase/reductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| Rv1929c Rv1929c |
mtbc0_002043 |
hypothetical protein | TIGR03085 family metal-binding protein. | Family assigned | |
| Rv1930c Rv1930c |
mtbc0_002044 |
hypothetical protein | Glutamine amidotransferase. | Resolved | |
| Rv1931c Rv1931c |
- |
transcriptional regulator | Transcriptional regulator. Pfam: DJ-1_PfpI (PF01965.31), HTH_18 (PF12833.14). | DJ-1_PfpI HTH_18 |
Family assigned |
| tpx Rv1932 |
mtbc0_002046 |
2-Cys peroxiredoxin | Thiol peroxidase. Pfam: Redoxin (PF08534.17), AhpC-TSA (PF00578.28). | Redoxin AhpC-TSA |
Resolved |
| fadE18 Rv1933c |
mtbc0_002047 |
acyl-CoA dehydrogenase FadE18 | Acyl-CoA dehydrogenase family protein. Pfam: Acyl-CoA_dh_N (PF02771.22), Acyl-CoA_dh_1 (PF00441.30), Acyl-CoA_dh_2 (PF08028.17). | Acyl-CoA_dh_N Acyl-CoA_dh_1 Acyl-CoA_dh_2 |
Family assigned |
| fadE17 Rv1934c |
mtbc0_002048 |
acyl-CoA dehydrogenase FadE17 | Acyl-CoA dehydrogenase. Pfam: Acyl-CoA_dh_N (PF02771.22), Acyl-CoA_dh_M (PF02770.25), Acyl-CoA_dh_1 (PF00441.30). | Acyl-CoA_dh_N Acyl-CoA_dh_M Acyl-CoA_dh_1 |
Resolved |
| echA13 Rv1935c |
mtbc0_002049 |
enoyl-CoA hydratase EchA13 | Enoyl-CoA hydratase. Pfam: ECH_2 (PF16113.11), ECH_1 (PF00378.26). | ECH_2 ECH_1 |
Resolved |
| Rv1936 Rv1936 |
mtbc0_002050 |
monooxygenase | LLM class flavin-dependent oxidoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Resolved |
| Rv1937 Rv1937 |
mtbc0_002051 |
oxygenase | FAD-binding oxidoreductase. Pfam: Fer2 (PF00111.33), FAD_binding_6 (PF00970.31), NAD_binding_1 (PF00175.27). | Fer2 FAD_binding_6 NAD_binding_1 |
Resolved |
| ephB Rv1938 |
mtbc0_002052 |
epoxide hydrolase EphB | Epoxide hydrolase EphB. Pfam: Abhydrolase_1 (PF00561.27), Hydrolase_4 (PF12146.16), Abhydrolase_6 (PF12697.14). | Abhydrolase_1 Hydrolase_4 Abhydrolase_6 |
Resolved |
| Rv1939 Rv1939 |
mtbc0_002053 |
oxidoreductase | Flavin reductase family protein. Pfam: Flavin_Reduct (PF01613.25). | Flavin_Reduct |
Family assigned |
| ribA1 Rv1940 |
- |
riboflavin biosynthesis protein RibA | Riboflavin biosynthesis protein RibA. Pfam: DHBP_synthase (PF00926.25), GTP_cyclohydro2 (PF00925.26). | DHBP_synthase GTP_cyclohydro2 |
Resolved |
| Rv1941 Rv1941 |
mtbc0_002055 |
short-chain type dehydrogenase/reductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| mazF5 Rv1942c |
mtbc0_002056 |
toxin MazF5 | Type II toxin-antitoxin system PemK/MazF family toxin. Pfam: PemK_toxin (PF02452.24). | PemK_toxin |
Family assigned |
| mazE5 Rv1943c |
mtbc0_002057 |
antitoxin MazE5 | Type II toxin-antitoxin system antitoxin MazE5. | Resolved | |
| Rv1944c Rv1944c |
mtbc0_002058 |
hypothetical protein | SEC-C domain-containing protein. Pfam: SEC-C (PF02810.22). | SEC-C |
Family assigned |
| Rv1945 Rv1945 |
mtbc0_001235 |
hypothetical protein | HNH endonuclease signature motif containing protein. Pfam: DUF222 (PF02720.23), HNH (PF01844.30). | DUF222 HNH |
Resolved |
| lppG Rv1946c |
mtbc0_002060 |
lipoprotein | Lipoprotein. | Family assigned | |
| Rv1947 Rv1947 |
mtbc0_002061 |
hypothetical protein | Superfamily-II helicase (eggNOG COG1061, DEAD/SNF2-like; COG categories K/L), in an RD (RDcap_Spain4) context. Helicase fold; biological role undetermined. | Family assigned | |
| Rv1948c Rv1948c |
mtbc0_001233 |
hypothetical protein | Suppressor-of-Fused-like fold (PDB 4KMA); fold characterised, function not established. | Family assigned | |
| Rv1950c Rv1950c |
mtbc0_002065 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1951c Rv1951c |
mtbc0_002066 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6z6f-assembly1_C HDAC-PC (prob 0.15, TM 0.64). | Still unknown | |
| vapB14 Rv1952 |
mtbc0_002067 |
antitoxin VapB14 | Antitoxin. Pfam: FitA-like_RHH (PF22513.3). | FitA-like_RHH |
Resolved |
| vapC14 Rv1953 |
- |
ribonuclease VapC14 | Ribonuclease VapC14. | Resolved | |
| Rv1954c Rv1954c |
mtbc0_002069 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3g02-assembly1_A Structure of enantioselective mutant of epoxide hydro (prob 0.04, TM 0.24). | Still unknown | |
| higB Rv1955 |
mtbc0_002070 |
toxin HigB | Type II toxin-antitoxin system toxin HigB. Pfam: Gp49 (PF05973.21). | Gp49 |
Resolved |
| higA Rv1956 |
mtbc0_002071 |
antitoxin HigA | Type II toxin-antitoxin system antitoxin HigA. Pfam: HTH_3 (PF01381.29). | HTH_3 |
Resolved |
| Rv1957 Rv1957 |
mtbc0_002072 |
SecB-like chaperone | SecB-like chaperone. | Resolved | |
| Rv1958c Rv1958c |
mtbc0_002073 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8zow-assembly1_c Cryo-EM structure of Metyltetraprole-bound porcine bc (prob 0.02, TM 0.23). | Still unknown | |
| parE1 Rv1959c |
mtbc0_002074 |
toxin ParE1 | Type II toxin-antitoxin system RelE/ParE family toxin. Pfam: ParE_toxin (PF05016.22). | ParE_toxin |
Family assigned |
| parD1 Rv1960c |
mtbc0_002075 |
antitoxin ParD1 | Type II toxin-antitoxin system ParD family antitoxin. Pfam: ParD_antitoxin (PF03693.21). | ParD_antitoxin |
Family assigned |
| Rv1961 Rv1961 |
mtbc0_002076 |
hypothetical protein | Superfamily-II helicase (eggNOG COG1061, DEAD/SNF2-like; COG category L). RefSeq leaves it 'hypothetical protein'. Helicase fold; biological role undetermined. | Family assigned |