Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1879 Rv1879 |
mtbc0_001993 |
hypothetical protein | Amidohydrolase family protein. Pfam: Amidohydro_2 (PF04909.21). | Amidohydro_2 |
Family assigned |
| cyp140 Rv1880c |
mtbc0_001994 |
cytochrome P450 Cyp140 | Cytochrome P450. Pfam: p450 (PF00067.28). | p450 |
Resolved |
| lppE Rv1881c |
mtbc0_001995 |
lipoprotein LppE | Lipoprotein LpqH. Pfam: Myco_19_kDa (PF05481.18). | Myco_19_kDa |
Resolved |
| Rv1882c Rv1882c |
mtbc0_001996 |
short-chain type dehydrogenase/reductase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), adh_short_C2 (PF13561.13). | adh_short adh_short_C2 |
Family assigned |
| Rv1883c Rv1883c |
mtbc0_001997 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16), Polyketide_cyc (PF03364.26). | Polyketide_cyc2 Polyketide_cyc |
Family assigned |
| rpfC Rv1884c |
mtbc0_001998 |
resuscitation-promoting factor RpfC | Resuscitation-promoting factor RpfC. Pfam: Transglycosylas (PF06737.20). | Transglycosylas |
Resolved |
| Rv1885c Rv1885c |
mtbc0_001999 |
chorismate mutase | Chorismate mutase. Pfam: CM_2 (PF01817.27). | CM_2 |
Resolved |
| fbpB Rv1886c |
mtbc0_002000 |
diacylglycerol acyltransferase/mycolyltransferase Ag85B | Diacylglycerol acyltransferase/mycolyltransferase Ag85B. Pfam: Esterase (PF00756.27). | Esterase |
Resolved |
| Rv1887 Rv1887 |
mtbc0_002001 |
hypothetical protein | Exopolyphosphatase-like fold (PDB 3HI0); putative phosphatase/hydrolase. | DUF7159 |
Family assigned |
| Rv1888A Rv1888A |
|
Conserved hypothetical protein | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity | LCM |
Family assigned |
| Rv1888c Rv1888c |
|
Possible transmembrane protein | Possible transmembrane protein | DUF4389 |
Family assigned |
| Rv1889c Rv1889c |
|
Conserved hypothetical protein | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity | LCM |
Family assigned |
| Rv1890c Rv1890c |
- |
hypothetical protein | Contains YceI (PF04264.19) domain(s); putative function inferred from the domain architecture. | YceI |
Family assigned |
| Rv1891 Rv1891 |
mtbc0_002005 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6xl5-assembly1_D Cryo-EM structure of EcmrR-RNAP-promoter open complex (prob 0.04, TM 0.37). | Still unknown | |
| Rv1892 Rv1892 |
mtbc0_002006 |
membrane protein | Small integral membrane protein, invariant across 145,209 genomes (2 segregating sites only — a constraint read from invariance itself, the pN/pS being unpowered here). Its fold WEAKLY resembles actinobacterial respiratory-supercomplex accessory subunits (HHpred 7E1V/7Q21, E~1-2, near the TM-helix promiscuity floor). Function undetermined; the supercomplex association is a weak structural hint only, uncorroborated. | Family assigned | |
| Rv1893 Rv1893 |
mtbc0_002007 |
hypothetical protein | Contains Rv1893 (PF23706.3) domain(s); putative function inferred from the domain architecture. | Rv1893 |
Family assigned |
| Rv1894c Rv1894c |
mtbc0_002008 |
hypothetical protein | Nitronate monooxygenase family protein. Pfam: NMO (PF03060.22). | NMO |
Family assigned |
| Rv1895 Rv1895 |
- |
zinc-binding alcohol dehydrogenase | Zinc-binding alcohol dehydrogenase. Pfam: ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13). | ADH_N ADH_zinc_N ADH_zinc_N_2 |
Resolved |
| Rv1896c Rv1896c |
mtbc0_002010 |
S-adenosyl-L-methionine-dependent methyltransferase | Class I SAM-dependent methyltransferase. Pfam: LCM (PF04072.21). | LCM |
Resolved |
| dtd Rv1897c |
mtbc0_002011 |
D-tyrosyl-tRNA(Tyr) deacylase | D-aminoacyl-tRNA deacylase. Pfam: Tyr_Deacylase (PF02580.22). | Tyr_Deacylase |
Resolved |
| Rv1898 Rv1898 |
mtbc0_002012 |
hypothetical protein | MTH1187 family thiamine-binding protein. Pfam: Thiamine_BP (PF01910.23). | Thiamine_BP |
Family assigned |
| lppD Rv1899c |
- |
lipoprotein LppD | Lipoprotein LppD. Pfam: Macro (PF01661.28). | Macro |
Resolved |
| lipJ Rv1900c |
mtbc0_002015 |
lignin peroxidase LipJ | Adenylate/guanylate cyclase domain-containing protein. Pfam: Abhydrolase_1 (PF00561.27), Guanylate_cyc (PF00211.26). | Abhydrolase_1 Guanylate_cyc |
Family assigned |
| cinA Rv1901 |
mtbc0_002016 |
competence damage-inducible protein CinA | Competence/damage-inducible protein A. Pfam: MoCF_biosynth (PF00994.30), CinA (PF02464.24). | MoCF_biosynth CinA |
Resolved |
| nanT Rv1902c |
mtbc0_002017 |
sialic acid-transport integral membrane protein NanT | Sialate:H+ symport family MFS transporter. Pfam: Sugar_tr (PF00083.31), MFS_1 (PF07690.22). | Sugar_tr MFS_1 |
Family assigned |
| Rv1903 Rv1903 |
mtbc0_002018 |
membrane protein | Phage holin family protein. Pfam: Phage_holin_4_2 (PF04020.19). | Phage_holin_4_2 |
Family assigned |
| Rv1904 Rv1904 |
mtbc0_002019 |
hypothetical protein | Anti-sigma factor antagonist. Pfam: STAS (PF01740.27), STAS_2 (PF13466.13). | STAS STAS_2 |
Resolved |
| aao Rv1905c |
mtbc0_002020 |
D-amino acid oxidase | FAD-dependent oxidoreductase. Pfam: DAO (PF01266.31), FAD_binding_2 (PF00890.31). | DAO FAD_binding_2 |
Resolved |
| Rv1906c Rv1906c |
mtbc0_002021 |
hypothetical protein | Contains Rv1352 (PF27111.1) domain(s); putative function inferred from the domain architecture. | Rv1352 |
Family assigned |
| Rv1907c Rv1907c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF4262. Function unknown. Foldseek best (non-significant) hit: 4q3o-assembly4_H Crystal structure of MGS-MT1, an alpha/beta hydrolase (prob 0.04, TM 0.35). | DUF4262 |
Still unknown |
| katG Rv1908c |
mtbc0_002023 |
catalase-peroxidase | Catalase/peroxidase HPI. Pfam: peroxidase (PF00141.29). | peroxidase |
Resolved |
| furA Rv1909c |
mtbc0_002024 |
ferric uptake regulation protein FurA | Fur family transcriptional regulator. Pfam: FUR (PF01475.26). | FUR |
Family assigned |
| Rv1910c Rv1910c |
mtbc0_002025 |
hypothetical protein | YbhB/YbcL family Raf kinase inhibitor-like protein. Pfam: PBP (PF01161.26). | PBP |
Family assigned |
| lppC Rv1911c |
mtbc0_002026 |
lipoprotein LppC | YbhB/YbcL family Raf kinase inhibitor-like protein. Pfam: PBP (PF01161.26). | PBP |
Family assigned |
| fadB5 Rv1912c |
mtbc0_002027 |
oxidoreductase FadB | Medium chain dehydrogenase/reductase family protein. Pfam: ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13). | ADH_N ADH_zinc_N ADH_zinc_N_2 |
Family assigned |
| Rv1913 Rv1913 |
mtbc0_002028 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B (PF00753.34). | Lactamase_B |
Resolved |
| Rv1914c Rv1914c |
mtbc0_002029 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 2ys5-assembly1_A Solution structure of the complex of the PTB domain o (prob 0.38, TM 0.51). | Still unknown | |
| aceAa Rv1915 |
- |
isocitrate lyase AceAa | Isocitrate lyase AceAa. Pfam: ICL (PF00463.28), PEP_mutase (PF13714.13). | ICL PEP_mutase |
Resolved |
| aceAb Rv1916 |
- |
isocitrate lyase AceAb | Isocitrate lyase AceAb. Pfam: ICL (PF00463.28). | ICL |
Resolved |
| PPE34 Rv1917c |
- |
PPE family protein PPE34 | PPE family protein PPE34. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| PPE35 Rv1918c |
- |
PPE family protein PPE35 | PPE family protein PPE35. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| Rv1919c Rv1919c |
mtbc0_002033 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv1920 Rv1920 |
mtbc0_002034 |
membrane protein | Lysophospholipid acyltransferase family protein. Pfam: Acyltransferase (PF01553.27), DAGAT (PF03982.19). | Acyltransferase DAGAT |
Family assigned |
| lppF Rv1921c |
mtbc0_002035 |
lipoprotein LppF | Haloacid dehalogenase-like hydrolase. Pfam: Hydrolase (PF00702.33), HAD (PF12710.14). | Hydrolase HAD |
Resolved |
| Rv1922 Rv1922 |
mtbc0_002036 |
lipoprotein | Serine hydrolase. Pfam: Beta-lactamase (PF00144.30). | Beta-lactamase |
Resolved |
| lipD Rv1923 |
- |
lipase LipD | Lipase LipD. Pfam: Beta-lactamase (PF00144.30). | Beta-lactamase |
Resolved |
| Rv1924c Rv1924c |
mtbc0_002038 |
hypothetical protein | Polytopic integral membrane protein with 3 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | Family assigned | |
| fadD31 Rv1925 |
mtbc0_002039 |
fatty-acid--CoA ligase FadD31 | Fatty-acid--AMP ligase FAAL31/FadD31. Pfam: AMP-binding (PF00501.35). | AMP-binding |
Resolved |
| mpt63 Rv1926c |
mtbc0_002040 |
immunogenic protein Mpt63 | Immunoprotective protein Mpt63. | DUF1942 |
Resolved |
| Rv1927 Rv1927 |
mtbc0_002041 |
hypothetical protein | YqjF family protein. | DUF2071 |
Family assigned |