Genes
1086 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1879 Rv1879 |
mtbc0_001993 |
hypothetical protein | Amidohydrolase family protein. Pfam: Amidohydro_2 (PF04909.21). | Amidohydro_2 |
Family assigned |
| Rv1883c Rv1883c |
mtbc0_001997 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16), Polyketide_cyc (PF03364.26). | Polyketide_cyc2 Polyketide_cyc |
Family assigned |
| Rv1887 Rv1887 |
mtbc0_002001 |
hypothetical protein | Exopolyphosphatase-like fold (PDB 3HI0); putative phosphatase/hydrolase. | DUF7159 |
Family assigned |
| Rv1888A Rv1888A |
|
Conserved hypothetical protein | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity | LCM |
Family assigned |
| Rv1889c Rv1889c |
|
Conserved hypothetical protein | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity | LCM |
Family assigned |
| Rv1890c Rv1890c |
- |
hypothetical protein | Contains YceI (PF04264.19) domain(s); putative function inferred from the domain architecture. | YceI |
Family assigned |
| Rv1891 Rv1891 |
mtbc0_002005 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6xl5-assembly1_D Cryo-EM structure of EcmrR-RNAP-promoter open complex (prob 0.04, TM 0.37). | Still unknown | |
| Rv1893 Rv1893 |
mtbc0_002007 |
hypothetical protein | Contains Rv1893 (PF23706.3) domain(s); putative function inferred from the domain architecture. | Rv1893 |
Family assigned |
| Rv1894c Rv1894c |
mtbc0_002008 |
hypothetical protein | Nitronate monooxygenase family protein. Pfam: NMO (PF03060.22). | NMO |
Family assigned |
| Rv1898 Rv1898 |
mtbc0_002012 |
hypothetical protein | MTH1187 family thiamine-binding protein. Pfam: Thiamine_BP (PF01910.23). | Thiamine_BP |
Family assigned |
| Rv1904 Rv1904 |
mtbc0_002019 |
hypothetical protein | Anti-sigma factor antagonist. Pfam: STAS (PF01740.27), STAS_2 (PF13466.13). | STAS STAS_2 |
Resolved |
| Rv1906c Rv1906c |
mtbc0_002021 |
hypothetical protein | Contains Rv1352 (PF27111.1) domain(s); putative function inferred from the domain architecture. | Rv1352 |
Family assigned |
| Rv1907c Rv1907c |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF4262. Function unknown. Foldseek best (non-significant) hit: 4q3o-assembly4_H Crystal structure of MGS-MT1, an alpha/beta hydrolase (prob 0.04, TM 0.35). | DUF4262 |
Still unknown |
| Rv1910c Rv1910c |
mtbc0_002025 |
hypothetical protein | YbhB/YbcL family Raf kinase inhibitor-like protein. Pfam: PBP (PF01161.26). | PBP |
Family assigned |
| Rv1913 Rv1913 |
mtbc0_002028 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B (PF00753.34). | Lactamase_B |
Resolved |
| Rv1914c Rv1914c |
mtbc0_002029 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 2ys5-assembly1_A Solution structure of the complex of the PTB domain o (prob 0.38, TM 0.51). | Still unknown | |
| Rv1919c Rv1919c |
mtbc0_002033 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv1924c Rv1924c |
mtbc0_002038 |
hypothetical protein | Polytopic integral membrane protein with 3 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | Family assigned | |
| Rv1927 Rv1927 |
mtbc0_002041 |
hypothetical protein | YqjF family protein. | DUF2071 |
Family assigned |
| Rv1929c Rv1929c |
mtbc0_002043 |
hypothetical protein | TIGR03085 family metal-binding protein. | Family assigned | |
| Rv1930c Rv1930c |
mtbc0_002044 |
hypothetical protein | Glutamine amidotransferase. | Resolved | |
| Rv1944c Rv1944c |
mtbc0_002058 |
hypothetical protein | SEC-C domain-containing protein. Pfam: SEC-C (PF02810.22). | SEC-C |
Family assigned |
| Rv1945 Rv1945 |
mtbc0_002059 |
hypothetical protein | HNH endonuclease signature motif containing protein. Pfam: DUF222 (PF02720.23), HNH (PF01844.30). | DUF222 HNH |
Resolved |
| Rv1947 Rv1947 |
mtbc0_002061 |
hypothetical protein | Superfamily-II helicase (eggNOG COG1061, DEAD/SNF2-like; COG categories K/L), in an RD (RDcap_Spain4) context. Helicase fold; biological role undetermined. | Family assigned | |
| Rv1948c Rv1948c |
mtbc0_002063 |
hypothetical protein | Suppressor-of-Fused-like fold (PDB 4KMA); fold characterised, function not established. | Family assigned | |
| Rv1949c Rv1949c |
|
Conserved hypothetical protein | — | Still unknown | |
| Rv1950c Rv1950c |
mtbc0_002065 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1951c Rv1951c |
mtbc0_002066 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6z6f-assembly1_C HDAC-PC (prob 0.15, TM 0.64). | Still unknown | |
| Rv1954A Rv1954A |
|
Hypothetical protein | — | Still unknown | |
| Rv1954c Rv1954c |
mtbc0_002069 |
hypothetical protein | Hypoxia-induced protein and empirically validated human T-cell antigen of the anti-TB response (Gideon 2012). Molecular function still undefined. | Resolved | |
| Rv1958c Rv1958c |
mtbc0_002073 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8zow-assembly1_c Cryo-EM structure of Metyltetraprole-bound porcine bc (prob 0.02, TM 0.23). | Still unknown | |
| Rv1961 Rv1961 |
mtbc0_002076 |
hypothetical protein | Superfamily-II helicase (eggNOG COG1061, DEAD/SNF2-like; COG category L). RefSeq leaves it 'hypothetical protein'. Helicase fold; biological role undetermined. | Family assigned | |
| Rv1975 Rv1975 |
mtbc0_002091 |
hypothetical protein | CAP domain-containing protein. Pfam: CAP (PF00188.33). | CAP |
Family assigned |
| Rv1976c Rv1976c |
mtbc0_002092 |
hypothetical protein | NYN domain-containing protein. Pfam: NYN_YacP (PF05991.18). | NYN_YacP |
Family assigned |
| Rv1977 Rv1977 |
mtbc0_002099 |
hypothetical protein | M48 family metallopeptidase. Pfam: Peptidase_M48 (PF01435.25). | Peptidase_M48 |
Family assigned |
| Rv1978 Rv1978 |
mtbc0_002100 |
hypothetical protein | Class I SAM-dependent methyltransferase. Pfam: Methyltransf_25 (PF13649.13), Methyltransf_12 (PF08242.19), Methyltransf_11 (PF08241.19). | Methyltransf_25 Methyltransf_12 Methyltransf_11 |
Resolved |
| Rv1984a Rv1984a |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 1n91-assembly1_A Solution NMR Structure of Protein yggU from Escherichia coli. N (prob 1.00, TM 0.70). Structure-based, putative. | DUF167 |
Family assigned |
| Rv1989c Rv1989c |
mtbc0_002113 |
hypothetical protein | RES family NAD+ phosphorylase. Pfam: RES (PF08808.18). | RES |
Family assigned |
| Rv1993c Rv1993c |
mtbc0_002120 |
hypothetical protein | DUF1490 family protein. | DUF1490 |
Family assigned |
| Rv1995 Rv1995 |
mtbc0_002122 |
hypothetical protein | Hemerythrin domain-containing protein. Pfam: Hemerythrin (PF01814.29). | Hemerythrin |
Family assigned |
| Rv1998c Rv1998c |
mtbc0_002125 |
hypothetical protein | Isocitrate lyase/phosphoenolpyruvate mutase family protein. Pfam: PEP_mutase (PF13714.13). | PEP_mutase |
Family assigned |
| Rv2000 Rv2000 |
mtbc0_002127 |
hypothetical protein | FAD/NAD(P)-binding protein. Pfam: NAD_binding_8 (PF13450.13). | NAD_binding_8 |
Family assigned |
| Rv2001 Rv2001 |
mtbc0_002128 |
hypothetical protein | Acyl-[acyl-carrier-protein] thioesterase. Pfam: Acyl-ACP_TE (PF01643.24), Acyl-ACP_TE_C (PF20791.4). | Acyl-ACP_TE Acyl-ACP_TE_C |
Resolved |
| Rv2003c Rv2003c |
- |
hypothetical protein | Contains Methyltransf_11 (PF08241.19), Methyltransf_25 (PF13649.13), Methyltransf_23 (PF13489.13) domain(s); putative function inferred from the domain architecture. | Methyltransf_11 Methyltransf_25 Methyltransf_23 |
Family assigned |
| Rv2004c Rv2004c |
mtbc0_002132 |
hypothetical protein | AAA family ATPase. Pfam: Zeta_toxin (PF06414.19), AAA_33 (PF13671.13). | Zeta_toxin AAA_33 |
Family assigned |
| Rv2008c Rv2008c |
- |
hypothetical protein | Contains AAA_14 (PF13173.13), DUF4143 (PF13635.13) domain(s); putative function inferred from the domain architecture. | AAA_14 DUF4143 |
Family assigned |
| Rv2011c Rv2011c |
mtbc0_002139 |
hypothetical protein | MarR family winged helix-turn-helix transcriptional regulator. Pfam: MarR_2 (PF12802.14). | MarR_2 |
Family assigned |
| Rv2012 Rv2012 |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 2hh8-assembly1_A Solution NMR structure of the ydfO protein from Escherichia col (prob 1.00, TM 0.74). Structure-based, putative. | DUF1398 |
Family assigned |
| Rv2015c Rv2015c |
mtbc0_002145 |
hypothetical protein | HNH endonuclease signature motif containing protein. Pfam: DUF222 (PF02720.23), HNH (PF01844.30). | DUF222 HNH |
Resolved |
| Rv2016 Rv2016 |
mtbc0_002146 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 2e2l-assembly1_E Helicobacter pylori formamidase AmiF contains a fine- (prob 0.13, TM 0.52). | Still unknown |