Genes
1051 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1913 Rv1913 |
mtbc0_002028 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B (PF00753.34). | Lactamase_B |
Resolved |
| Rv1914c Rv1914c |
mtbc0_002029 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 2ys5-assembly1_A Solution structure of the complex of the PTB domain o (prob 0.38, TM 0.51). | Still unknown | |
| Rv1919c Rv1919c |
mtbc0_002033 |
hypothetical protein | SRPBCC family protein. Pfam: Polyketide_cyc2 (PF10604.16). | Polyketide_cyc2 |
Family assigned |
| Rv1924c Rv1924c |
mtbc0_002038 |
hypothetical protein | Polytopic integral membrane protein with 3 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | Family assigned | |
| Rv1927 Rv1927 |
mtbc0_002041 |
hypothetical protein | YqjF family protein. | DUF2071 |
Family assigned |
| Rv1929c Rv1929c |
mtbc0_002043 |
hypothetical protein | TIGR03085 family metal-binding protein. | Family assigned | |
| Rv1930c Rv1930c |
mtbc0_002044 |
hypothetical protein | Glutamine amidotransferase. | Resolved | |
| Rv1944c Rv1944c |
mtbc0_002058 |
hypothetical protein | SEC-C domain-containing protein. Pfam: SEC-C (PF02810.22). | SEC-C |
Family assigned |
| Rv1945 Rv1945 |
mtbc0_001235 |
hypothetical protein | HNH endonuclease signature motif containing protein. Pfam: DUF222 (PF02720.23), HNH (PF01844.30). | DUF222 HNH |
Resolved |
| Rv1947 Rv1947 |
mtbc0_002061 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8ro2-assembly1_M Integrative Structure of the human intron lariat Spli (prob 0.04, TM 0.29). | Still unknown | |
| Rv1948c Rv1948c |
mtbc0_001233 |
hypothetical protein | Suppressor-of-Fused-like fold (PDB 4KMA); fold characterised, function not established. | Family assigned | |
| Rv1950c Rv1950c |
mtbc0_002065 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv1951c Rv1951c |
mtbc0_002066 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 6z6f-assembly1_C HDAC-PC (prob 0.15, TM 0.64). | Still unknown | |
| Rv1954c Rv1954c |
mtbc0_002069 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3g02-assembly1_A Structure of enantioselective mutant of epoxide hydro (prob 0.04, TM 0.24). | Still unknown | |
| Rv1958c Rv1958c |
mtbc0_002073 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8zow-assembly1_c Cryo-EM structure of Metyltetraprole-bound porcine bc (prob 0.02, TM 0.23). | Still unknown | |
| Rv1961 Rv1961 |
mtbc0_002076 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 5umr-assembly1_A Crystal structure of N-terminal domain of human FACT (prob 0.33, TM 0.74). | Still unknown | |
| Rv1975 Rv1975 |
mtbc0_002091 |
hypothetical protein | CAP domain-containing protein. Pfam: CAP (PF00188.33). | CAP |
Family assigned |
| Rv1976c Rv1976c |
mtbc0_002092 |
hypothetical protein | NYN domain-containing protein. Pfam: NYN_YacP (PF05991.18). | NYN_YacP |
Family assigned |
| Rv1977 Rv1977 |
mtbc0_002099 |
hypothetical protein | M48 family metallopeptidase. Pfam: Peptidase_M48 (PF01435.25). | Peptidase_M48 |
Family assigned |
| Rv1978 Rv1978 |
mtbc0_002100 |
hypothetical protein | Class I SAM-dependent methyltransferase. Pfam: Methyltransf_25 (PF13649.13), Methyltransf_12 (PF08242.19), Methyltransf_11 (PF08241.19). | Methyltransf_25 Methyltransf_12 Methyltransf_11 |
Resolved |
| Rv1984a Rv1984a |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 1n91-assembly1_A Solution NMR Structure of Protein yggU from Escherichia coli. N (prob 1.00, TM 0.70). Structure-based, putative. | DUF167 |
Family assigned |
| Rv1989c Rv1989c |
mtbc0_002113 |
hypothetical protein | RES family NAD+ phosphorylase. Pfam: RES (PF08808.18). | RES |
Family assigned |
| Rv1993c Rv1993c |
mtbc0_002120 |
hypothetical protein | DUF1490 family protein. | DUF1490 |
Family assigned |
| Rv1995 Rv1995 |
mtbc0_002122 |
hypothetical protein | Hemerythrin domain-containing protein. Pfam: Hemerythrin (PF01814.29). | Hemerythrin |
Family assigned |
| Rv1998c Rv1998c |
mtbc0_002125 |
hypothetical protein | Isocitrate lyase/phosphoenolpyruvate mutase family protein. Pfam: PEP_mutase (PF13714.13). | PEP_mutase |
Family assigned |
| Rv2000 Rv2000 |
mtbc0_002127 |
hypothetical protein | FAD/NAD(P)-binding protein. Pfam: NAD_binding_8 (PF13450.13). | NAD_binding_8 |
Family assigned |
| Rv2001 Rv2001 |
mtbc0_002128 |
hypothetical protein | Acyl-[acyl-carrier-protein] thioesterase. Pfam: Acyl-ACP_TE (PF01643.24), Acyl-ACP_TE_C (PF20791.4). | Acyl-ACP_TE Acyl-ACP_TE_C |
Resolved |
| Rv2003c Rv2003c |
- |
hypothetical protein | Contains Methyltransf_11 (PF08241.19), Methyltransf_25 (PF13649.13), Methyltransf_23 (PF13489.13) domain(s); putative function inferred from the domain architecture. | Methyltransf_11 Methyltransf_25 Methyltransf_23 |
Family assigned |
| Rv2004c Rv2004c |
mtbc0_002132 |
hypothetical protein | AAA family ATPase. Pfam: Zeta_toxin (PF06414.19), AAA_33 (PF13671.13). | Zeta_toxin AAA_33 |
Family assigned |
| Rv2008c Rv2008c |
- |
hypothetical protein | Contains AAA_14 (PF13173.13), DUF4143 (PF13635.13) domain(s); putative function inferred from the domain architecture. | AAA_14 DUF4143 |
Family assigned |
| Rv2011c Rv2011c |
mtbc0_002139 |
hypothetical protein | MarR family winged helix-turn-helix transcriptional regulator. Pfam: MarR_2 (PF12802.14). | MarR_2 |
Family assigned |
| Rv2012 Rv2012 |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 2hh8-assembly1_A Solution NMR structure of the ydfO protein from Escherichia col (prob 1.00, TM 0.74). Structure-based, putative. | DUF1398 |
Family assigned |
| Rv2015c Rv2015c |
mtbc0_001879 |
hypothetical protein | HNH endonuclease signature motif containing protein. Pfam: DUF222 (PF02720.23), HNH (PF01844.30). | DUF222 HNH |
Resolved |
| Rv2016 Rv2016 |
mtbc0_002146 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 2e2l-assembly1_E Helicobacter pylori formamidase AmiF contains a fine- (prob 0.13, TM 0.52). | Still unknown | |
| Rv2018 Rv2018 |
mtbc0_002148 |
hypothetical protein | DUF433 domain-containing protein. Pfam: HTH_66 (PF21321.4), DUF433 (PF04255.21). | HTH_66 DUF433 |
Family assigned |
| Rv2019 Rv2019 |
mtbc0_002149 |
hypothetical protein | Contains PIN_10 (PF18478.8) domain(s); putative function inferred from the domain architecture. | PIN_10 |
Family assigned |
| Rv2022c Rv2022c |
mtbc0_002152 |
hypothetical protein | Type II toxin-antitoxin system RelE/ParE family toxin. Pfam: Gp49 (PF05973.21). | Gp49 |
Family assigned |
| Rv2023c Rv2023c |
mtbc0_002153 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2024c Rv2024c |
- |
hypothetical protein | Contains Mrr_cat (PF04471.19), Mrr_cat_2 (PF13156.13), ResIII (PF04851.22), DEAD (PF00270.36) domain(s); putative function inferred from the domain architecture. | Mrr_cat Mrr_cat_2 ResIII DEAD |
Family assigned |
| Rv2030c Rv2030c |
mtbc0_002163 |
hypothetical protein | Erythromycin esterase family protein. Pfam: Pribosyltran (PF00156.34), Erythro_esteras (PF05139.20). | Pribosyltran Erythro_esteras |
Family assigned |
| Rv2033c Rv2033c |
mtbc0_002166 |
hypothetical protein | DUF3097; Foldseek best hit (OLD protein, TM 0.49) not conclusive. Function unknown. | DUF3097_N DUF3097_C |
Still unknown |
| Rv2035 Rv2035 |
mtbc0_002168 |
hypothetical protein | SRPBCC family protein. Pfam: AHSA1 (PF08327.18). | AHSA1 |
Family assigned |
| Rv2036 Rv2036 |
mtbc0_002169 |
hypothetical protein | Maleylpyruvate isomerase family mycothiol-dependent enzyme. Pfam: MDMPI_N (PF11716.14). | MDMPI_N |
Family assigned |
| Rv2042c Rv2042c |
mtbc0_002175 |
hypothetical protein | Ketosteroid isomerase family protein. Pfam: NTF2 (PF02136.27), SnoaL_2 (PF12680.14). | NTF2 SnoaL_2 |
Family assigned |
| Rv2044c Rv2044c |
- |
hypothetical protein | Polytopic integral membrane protein with 3 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | DUF2784 |
Family assigned |
| Rv2047c Rv2047c |
mtbc0_002180 |
hypothetical protein | Sugar epimerase family protein. Pfam: Epimerase (PF01370.28), 3Beta_HSD (PF01073.26), NAD_binding_10 (PF13460.13), Rph_4th (PF27448.1), PEP-utilizers (PF00391.30). | Epimerase 3Beta_HSD NAD_binding_10 Rph_4th PEP-utilizers |
Family assigned |
| Rv2049c Rv2049c |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 5lcy-assembly1_C Formaldehyde-Responsive Regulator FrmR E64H variant from Salmon (prob 1.00, TM 0.90). Structure-based, putative. | Family assigned | |
| Rv2052c Rv2052c |
mtbc0_002185 |
hypothetical protein | Amidohydrolase. Pfam: Amidohydro_3 (PF07969.18). | Amidohydro_3 |
Resolved |
| Rv2054 Rv2054 |
mtbc0_002187 |
hypothetical protein | Dienelactone hydrolase family protein. Pfam: DLH (PF01738.25). | DLH |
Family assigned |
| Rv2059 Rv2059 |
- |
hypothetical protein | Contains ZnuA (PF01297.23) domain(s); putative function inferred from the domain architecture. | ZnuA |
Family assigned |