Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| pknI Rv2914c |
mtbc0_003096 |
serine/threonine-protein kinase PknI | Serine/threonine protein kinase PknI. Pfam: Pkinase (PF00069.32), PK_Tyr_Ser-Thr (PF07714.24). | Pkinase PK_Tyr_Ser-Thr |
Resolved |
| Rv2915c Rv2915c |
mtbc0_003097 |
hypothetical protein | Amidohydrolase family protein. Pfam: Amidohydro_1 (PF01979.27). | Amidohydro_1 |
Family assigned |
| ffh Rv2916c |
mtbc0_003098 |
signal recognition particle protein | Signal recognition particle protein. Pfam: SRP54_N (PF02881.25), SRP54 (PF00448.29), SRP_SPB (PF02978.27). | SRP54_N SRP54 SRP_SPB |
Resolved |
| Rv2917 Rv2917 |
- |
hypothetical protein | Contains ResIII (PF04851.22), DEAD (PF00270.36), SWI2_SNF2 (PF18766.8) domain(s); putative function inferred from the domain architecture. | ResIII DEAD SWI2_SNF2 |
Family assigned |
| glnD Rv2918c |
mtbc0_003100 |
bifunctional uridylyltransferase/uridylyl-removing enzyme | [protein-PII] uridylyltransferase. Pfam: GlnD_UR_UTase (PF08335.17), HD (PF01966.29). | GlnD_UR_UTase HD |
Resolved |
| glnB Rv2919c |
mtbc0_003101 |
nitrogen regulatory protein P-II | Nitrogen regulatory protein P-II. Pfam: P-II (PF00543.28). | P-II |
Family assigned |
| amt Rv2920c |
mtbc0_003102 |
ammonium transporter integral membrane protein | Ammonium transporter. Pfam: Ammonium_transp (PF00909.27). | Ammonium_transp |
Resolved |
| ftsY Rv2921c |
mtbc0_003103 |
signal recognition particle receptor FtsY | Signal recognition particle-docking protein FtsY. Pfam: SRP54_N (PF02881.25), SRP54 (PF00448.29), AAA_30 (PF13604.13). | SRP54_N SRP54 AAA_30 |
Resolved |
| acyP Rv2922A |
- |
acylphosphatase | Acylphosphatase. Pfam: Acylphosphatase (PF00708.25). | Acylphosphatase |
Resolved |
| smc Rv2922c |
mtbc0_003104 |
chromosome partition protein Smc | Chromosome segregation protein SMC. Pfam: AAA_15 (PF13175.13), SMC_N (PF02463.26), AAA_23 (PF13476.13), SMC_hinge (PF06470.19), AAA_21 (PF13304.13). | AAA_15 SMC_N AAA_23 SMC_hinge AAA_21 |
Resolved |
| Rv2923c Rv2923c |
mtbc0_003106 |
hypothetical protein | OsmC family protein. Pfam: OsmC (PF02566.25). | OsmC |
Family assigned |
| fpg Rv2924c |
mtbc0_003107 |
formamidopyrimidine-DNA glycosylase | DNA-formamidopyrimidine glycosylase. Pfam: Fapy_DNA_glyco (PF01149.30), H2TH (PF06831.20), zf-FPG_IleRS (PF06827.21). | Fapy_DNA_glyco H2TH zf-FPG_IleRS |
Resolved |
| rnc Rv2925c |
mtbc0_003108 |
ribonuclease III | Ribonuclease III. Pfam: Ribonucleas_3_3 (PF14622.12), Ribonuclease_3 (PF00636.32), dsrm (PF00035.33). | Ribonucleas_3_3 Ribonuclease_3 dsrm |
Resolved |
| Rv2926c Rv2926c |
- |
hypothetical protein | Contains YceD (PF02620.23) domain(s); putative function inferred from the domain architecture. | YceD |
Family assigned |
| sepIVA Rv2927c |
mtbc0_003110 |
hypothetical protein | Cell division protein SepIVA. | Resolved | |
| tesA Rv2928 |
mtbc0_003111 |
thioesterase TesA | Thioesterase TesA. Pfam: Thioesterase (PF00975.27), Abhydrolase_6 (PF12697.14). | Thioesterase Abhydrolase_6 |
Resolved |
| Rv2929 Rv2929 |
mtbc0_003112 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| fadD26 Rv2930 |
mtbc0_003113 |
fatty-acid--CoA ligase FadD26 | Long-chain-fatty-acid--AMP ligase FAAL26/FadD26. Pfam: AMP-binding (PF00501.35), AMP-dom_DIP2-like (PF23024.2). | AMP-binding AMP-dom_DIP2-like |
Resolved |
| ppsA Rv2931 |
mtbc0_003114 |
phthiocerol synthesis polyketide synthase type I PpsA | Phthiocerol type I polyketide synthase PpsA. Pfam: ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), KR (PF08659.17), PP-binding (PF00550.32). | ketoacyl-synt Ketoacyl-synt_C KAsynt_C_assoc Acyl_transf_1 PKS_DH_N KR PP-binding |
Resolved |
| ppsB Rv2932 |
mtbc0_003115 |
phthiocerol synthesis polyketide synthase type I PpsB | Phthiocerol type I polyketide synthase PpsB. Pfam: ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), Acyl_transf_1 (PF00698.27), SpnB_Rossmann (PF22953.4), KR (PF08659.17), adh_short (PF00106.32), PP-binding (PF00550.32). | ketoacyl-synt Ketoacyl-synt_C KAsynt_C_assoc Acyl_transf_1 SpnB_Rossmann KR adh_short PP-binding |
Resolved |
| ppsC Rv2933 |
mtbc0_003116 |
phthiocerol synthesis polyketide synthase type I PpsC | Phthiocerol type I polyketide synthase PpsC. Pfam: ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13), KR (PF08659.17), adh_short (PF00106.32), adh_short_C2 (PF13561.13), PP-binding (PF00550.32). | ketoacyl-synt Ketoacyl-synt_C Acyl_transf_1 PKS_DH_N PS-DH ADH_N ADH_zinc_N ADH_zinc_N_2 KR adh_short adh_short_C2 PP-binding |
Resolved |
| ppsD Rv2934 |
mtbc0_003117 |
phthiocerol synthesis polyketide synthase type I PpsD | Phthiocerol type I polyketide synthase PpsD. Pfam: ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), KR (PF08659.17), adh_short (PF00106.32), adh_short_C2 (PF13561.13), PP-binding (PF00550.32). | ketoacyl-synt Ketoacyl-synt_C KAsynt_C_assoc Acyl_transf_1 PKS_DH_N PS-DH KR adh_short adh_short_C2 PP-binding |
Resolved |
| ppsE Rv2935 |
mtbc0_003118 |
phthiocerol synthesis polyketide synthase type I PpsE | Phthiocerol type I polyketide synthase PpsE. Pfam: ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), CurL-like_PKS_C (PF22621.3), Acyl_transf_1 (PF00698.27), PP-binding (PF00550.32), Condensation (PF00668.26). | ketoacyl-synt Ketoacyl-synt_C KAsynt_C_assoc CurL-like_PKS_C Acyl_transf_1 PP-binding Condensation |
Resolved |
| drrA Rv2936 |
mtbc0_003119 |
daunorubicin ABC transporter ATP-binding protein DrrA | Daunorubicin ABC transporter ATP-binding protein DrrA. Pfam: ABC_tran (PF00005.34). | ABC_tran |
Family assigned |
| drrB Rv2937 |
mtbc0_003120 |
daunorubicin ABC transporter permease DrrB | Daunorubicin ABC transporter permease DrrB. Pfam: ABC2_membrane_3 (PF12698.14). | ABC2_membrane_3 |
Family assigned |
| drrC Rv2938 |
mtbc0_003121 |
daunorubicin ABC transporter permease DrrC | ABC transporter permease. Pfam: ABC2_membrane (PF01061.30), ABC2_membrane_3 (PF12698.14). | ABC2_membrane ABC2_membrane_3 |
Family assigned |
| papA5 Rv2939 |
mtbc0_003122 |
phthiocerol/phthiodiolone dimycocerosyl transferase | Phthiocerol/phthiodiolone dimycocerosyl transferase. Pfam: PapA_C (PF16911.11). | PapA_C |
Resolved |
| mas Rv2940c |
mtbc0_003123 |
multifunctional mycocerosic acid synthase | Mycocerosate synthase. Pfam: ketoacyl-synt (PF00109.33), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), CurL-like_PKS_C (PF22621.3), RhiE-like_linker (PF22336.3), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13), KR (PF08659.17), adh_short (PF00106.32), PP-binding (PF00550.32). | ketoacyl-synt Ketoacyl-synt_C KAsynt_C_assoc CurL-like_PKS_C RhiE-like_linker Acyl_transf_1 PKS_DH_N PS-DH ADH_N ADH_zinc_N ADH_zinc_N_2 KR adh_short PP-binding |
Resolved |
| fadD28 Rv2941 |
mtbc0_003124 |
long-chain-fatty-acid--AMP ligase FadD28 | Fatty-acid--AMP ligase FAAL28/FadD28. Pfam: AMP-binding (PF00501.35), AMP-dom_DIP2-like (PF23024.2). | AMP-binding AMP-dom_DIP2-like |
Resolved |
| mmpL7 Rv2942 |
mtbc0_003125 |
transmembrane transport protein MmpL7 | Phthiocerol dimycocerosate RND transporter MmpL7. Pfam: MMPL (PF03176.22). | MMPL |
Resolved |
| Rv2943 Rv2943 |
- |
insertion sequence element IS1533 transposase | Insertion sequence element IS1533 transposase. Pfam: rve (PF00665.33), Mu-transpos_C_2 (PF22483.3). | rve Mu-transpos_C_2 |
Resolved |
| Rv2943A Rv2943A |
- |
transposase | Transposase. Pfam: IstB_IS21 (PF01695.24). | IstB_IS21 |
Resolved |
| Rv2944 Rv2944 |
- |
insertion sequence element IS1533 transposase | Insertion sequence element IS1533 transposase. Pfam: Bac_DnaA (PF00308.25), IstB_IS21 (PF01695.24). | Bac_DnaA IstB_IS21 |
Resolved |
| lppX Rv2945c |
mtbc0_003128 |
lipoprotein LppX | LppX_LprAFG lipoprotein. Pfam: LppX_LprAFG (PF07161.20). | LppX_LprAFG |
Resolved |
| pks1 Rv2946c |
- |
polyketide synthase | Polyketide synthase. Pfam: CurL-like_PKS_C (PF22621.3), Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), SpnB_Rossmann (PF22953.4), ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13), KR (PF08659.17), adh_short (PF00106.32), Epimerase (PF01370.28), adh_short_C2 (PF13561.13), PP-binding (PF00550.32). | CurL-like_PKS_C Acyl_transf_1 PKS_DH_N PS-DH SpnB_Rossmann ADH_N ADH_zinc_N ADH_zinc_N_2 KR adh_short Epimerase adh_short_C2 PP-binding |
Resolved |
| pks15 Rv2947c |
- |
polyketide synthase | Polyketide synthase. Pfam: ketoacyl-synt (PF00109.33), Thiolase_N (PF00108.30), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12). | ketoacyl-synt Thiolase_N Ketoacyl-synt_C KAsynt_C_assoc |
Resolved |
| fadD22 Rv2948c |
mtbc0_003130 |
p-hydroxybenzoyl--AMP ligase | P-hydroxybenzoic acid--AMP ligase FadD22. Pfam: AMP-binding (PF00501.35), AMP-binding_C (PF13193.13), PP-binding (PF00550.32). | AMP-binding AMP-binding_C PP-binding |
Resolved |
| Rv2949c Rv2949c |
mtbc0_003131 |
chorismate pyruvate-lyase | Chorismate pyruvate-lyase family protein. Pfam: Rv2949c-like (PF01947.22). | Rv2949c-like |
Family assigned |
| fadD29 Rv2950c |
- |
long-chain-fatty-acid--AMP ligase FadD29 | Long-chain-fatty-acid--AMP ligase FadD29. Pfam: AMP-binding (PF00501.35), AMP-dom_DIP2-like (PF23024.2). | AMP-binding AMP-dom_DIP2-like |
Resolved |
| Rv2951c Rv2951c |
mtbc0_003133 |
phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase | Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase. Pfam: Bac_luciferase (PF00296.27). | Bac_luciferase |
Resolved |
| Rv2952 Rv2952 |
mtbc0_003134 |
phthiotriol/phenolphthiotriol dimycocerosates methyltransferase | Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase. Pfam: Methyltransf_23 (PF13489.13), Ubie_methyltran (PF01209.25), Methyltransf_31 (PF13847.13), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19), Methyltransf_12 (PF08242.19). | Methyltransf_23 Ubie_methyltran Methyltransf_31 Methyltransf_25 Methyltransf_11 Methyltransf_12 |
Resolved |
| Rv2953 Rv2953 |
mtbc0_003135 |
trans-acting enoyl reductase | Trans-acting enoyl reductase. Pfam: Sacchrp_dh_NADP (PF03435.25). | Sacchrp_dh_NADP |
Resolved |
| Rv2954c Rv2954c |
mtbc0_003136 |
hypothetical protein | [2%2C4-di-O-methyl-alpha-L-fucopyranosyl-(1->3)-alpha-L-rhamnopyranosyl-(1->3)-2-O-methyl-alpha-L-rhamnopyranosyl] dimycocerosyl phenol-phthiocerol 3'''-O-methyltransferase. Pfam: Methyltransf_23 (PF13489.13), Methyltransf_9 (PF08003.18), Methyltransf_25 (PF13649.13), Methyltransf_12 (PF08242.19), Methyltransf_11 (PF08241.19). | Methyltransf_23 Methyltransf_9 Methyltransf_25 Methyltransf_12 Methyltransf_11 |
Resolved |
| Rv2955c Rv2955c |
mtbc0_003137 |
hypothetical protein | [2-O-methyl-alpha-L-fucopyranosyl-(1->3)-alpha-L-rhamnopyranosyl-(1->3)-2-O-methyl-alpha-L-rhamnopyranosyl] dimycocerosyl phenol-phthiocerol 4'''-O-methyltransferase. Pfam: Methyltransf_21 (PF05050.20). | Methyltransf_21 |
Resolved |
| Rv2956 Rv2956 |
mtbc0_003138 |
hypothetical protein | [alpha-L-fucopyranosyl-(1->3)-alpha-L-rhamnopyranosyl-(1->3)-2-O-methyl-alpha-L-rhamnopyranosyl] dimycocerosyl phenol-phthiocerol 2'''-O-methyltransferase. Pfam: Methyltransf_21 (PF05050.20). | Methyltransf_21 |
Resolved |
| Rv2957 Rv2957 |
mtbc0_003139 |
PGL/p-HBAD biosynthesis glycosyltransferase | PGL/p-HBAD biosynthesis glycosyltransferase. Pfam: Glyco_tranf_2_3 (PF13641.13), Glycos_transf_2 (PF00535.33). | Glyco_tranf_2_3 Glycos_transf_2 |
Resolved |
| Rv2958c Rv2958c |
mtbc0_003141 |
PGL/p-HBAD biosynthesis glycosyltransferase | PGL/p-HBAD biosynthesis glycosyltransferase. Pfam: Glyco_tran_28_C (PF04101.23), UDPGT (PF00201.25), EryCIII-like_C (PF06722.19). | Glyco_tran_28_C UDPGT EryCIII-like_C |
Resolved |
| Rv2959c Rv2959c |
mtbc0_003142 |
rhamnosyl O-methyltransferase | Rhamnosyl O-methyltransferase. Pfam: RMNT_CmcI (PF04989.19), Methyltransf_24 (PF13578.13). | RMNT_CmcI Methyltransf_24 |
Resolved |
| Rv2960c Rv2960c |
mtbc0_003143 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2961 Rv2961 |
- |
transposase | Transposase. Pfam: DDE_Tnp_1 (PF01609.28). | DDE_Tnp_1 |
Resolved |