Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1976c Rv1976c |
mtbc0_002092 |
hypothetical protein | NYN domain-containing protein. Pfam: NYN_YacP (PF05991.18). | NYN_YacP |
Family assigned |
| Rv1977 Rv1977 |
mtbc0_002099 |
hypothetical protein | M48 family metallopeptidase. Pfam: Peptidase_M48 (PF01435.25). | Peptidase_M48 |
Family assigned |
| Rv1978 Rv1978 |
mtbc0_002100 |
hypothetical protein | Class I SAM-dependent methyltransferase. Pfam: Methyltransf_25 (PF13649.13), Methyltransf_12 (PF08242.19), Methyltransf_11 (PF08241.19). | Methyltransf_25 Methyltransf_12 Methyltransf_11 |
Resolved |
| Rv1979c Rv1979c |
mtbc0_002101 |
permease | APC family permease. Pfam: AA_permease_2 (PF13520.13), AA_permease (PF00324.28). | AA_permease_2 AA_permease |
Family assigned |
| mpt64 Rv1980c |
mtbc0_002102 |
immunogenic protein Mpt64 | Immunoprotective protein Mpt64. | DUF3298 |
Resolved |
| nrdF1 Rv1981c |
- |
ribonucleoside-diphosphate reductase subunit beta NrdF1 | Ribonucleoside-diphosphate reductase subunit beta NrdF1. Pfam: Ribonuc_red_sm (PF00268.28). | Ribonuc_red_sm |
Family assigned |
| vapB36 Rv1982A |
- |
antitoxin VapB36 | Antitoxin VapB36. Pfam: PSK_trans_fac (PF07704.18). | PSK_trans_fac |
Resolved |
| vapC36 Rv1982c |
mtbc0_002104 |
ribonuclease VapC36 | Type II toxin-antitoxin system VapC family toxin. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| PE_PGRS35 Rv1983 |
- |
PE-PGRS family protein PE_PGRS35 | PE-PGRS family protein PE_PGRS35. Pfam: PE (PF00934.26), PGRS (PF21526.3), PE-PGRS_C (PF20729.3). | PE PGRS PE-PGRS_C |
Family assigned |
| Rv1984a Rv1984a |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 1n91-assembly1_A Solution NMR Structure of Protein yggU from Escherichia coli. N (prob 1.00, TM 0.70). Structure-based, putative. | DUF167 |
Family assigned |
| cfp21 Rv1984c |
mtbc0_002107 |
cutinase | Cutinase Cfp21. Pfam: Cutinase (PF01083.29). | Cutinase |
Resolved |
| Rv1985c Rv1985c |
mtbc0_002109 |
HTH-type transcriptional regulator | ArgP/LysG family DNA-binding transcriptional regulator. Pfam: HTH_1 (PF00126.34), LysR_substrate (PF03466.26). | HTH_1 LysR_substrate |
Family assigned |
| lysE Rv1986 |
mtbc0_002110 |
amino acid transporter | L-lysine exporter. Pfam: LysE (PF01810.25). | LysE |
Resolved |
| Rv1987 Rv1987 |
mtbc0_002111 |
chitinase | Cellulose-binding protein. Pfam: CBM_2 (PF00553.26). | CBM_2 |
Family assigned |
| erm(37) Rv1988 |
- |
23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(37) | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(37). Pfam: RrnaAD (PF00398.27), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19). | RrnaAD Methyltransf_25 Methyltransf_11 |
Resolved |
| Rv1989c Rv1989c |
mtbc0_002113 |
hypothetical protein | RES family NAD+ phosphorylase. Pfam: RES (PF08808.18). | RES |
Family assigned |
| Rv1990c Rv1990c |
mtbc0_002114 |
transcriptional regulator | Antitoxin Xre/MbcA/ParS toxin-binding domain-containing protein. Pfam: Xre_MbcA_ParS_C (PF09722.16). | Xre_MbcA_ParS_C |
Family assigned |
| mazE6 Rv1991A |
- |
antitoxin MazE6 | Antitoxin MazE6. | Resolved | |
| mazF6 Rv1991c |
mtbc0_002117 |
mRNA interferase MazF6 | Type II toxin-antitoxin system toxin endoribonuclease MazF6. Pfam: PemK_toxin (PF02452.24). | PemK_toxin |
Resolved |
| ctpG Rv1992c |
mtbc0_002119 |
cation transporter ATPase G | Cation transporter ATPase CptG. Pfam: E1-E2_ATPase (PF00122.26), Hydrolase (PF00702.33). | E1-E2_ATPase Hydrolase |
Resolved |
| Rv1993c Rv1993c |
mtbc0_002120 |
hypothetical protein | DUF1490 family protein. | DUF1490 |
Family assigned |
| cmtR Rv1994c |
mtbc0_002121 |
HTH-type transcriptional regulator CmtR | Cd(II)/Pb(II)-sensing metalloregulatory transcriptional regulator CmtR. Pfam: HTH_20 (PF12840.14), HTH_5 (PF01022.27). | HTH_20 HTH_5 |
Family assigned |
| Rv1995 Rv1995 |
mtbc0_002122 |
hypothetical protein | Hemerythrin domain-containing protein. Pfam: Hemerythrin (PF01814.29). | Hemerythrin |
Family assigned |
| Rv1996 Rv1996 |
mtbc0_002123 |
universal stress protein | Universal stress protein. Pfam: Usp (PF00582.33). | Usp |
Resolved |
| ctpF Rv1997 |
mtbc0_002124 |
cation transporter ATPase F | Cation-transporting P-type ATPase. Pfam: Cation_ATPase_N (PF00690.32), E1-E2_ATPase (PF00122.26), Hydrolase (PF00702.33), Cation_ATPase (PF13246.13), Hydrolase_3 (PF08282.19), Cation_ATPase_C (PF00689.27). | Cation_ATPase_N E1-E2_ATPase Hydrolase Cation_ATPase Hydrolase_3 Cation_ATPase_C |
Resolved |
| Rv1998c Rv1998c |
mtbc0_002125 |
hypothetical protein | Isocitrate lyase/phosphoenolpyruvate mutase family protein. Pfam: PEP_mutase (PF13714.13). | PEP_mutase |
Family assigned |
| Rv1999c Rv1999c |
mtbc0_002126 |
transporter | APC family permease. Pfam: AA_permease_2 (PF13520.13), AA_permease (PF00324.28). | AA_permease_2 AA_permease |
Family assigned |
| Rv2000 Rv2000 |
mtbc0_002127 |
hypothetical protein | FAD/NAD(P)-binding protein. Pfam: NAD_binding_8 (PF13450.13). | NAD_binding_8 |
Family assigned |
| Rv2001 Rv2001 |
mtbc0_002128 |
hypothetical protein | Acyl-[acyl-carrier-protein] thioesterase. Pfam: Acyl-ACP_TE (PF01643.24), Acyl-ACP_TE_C (PF20791.4). | Acyl-ACP_TE Acyl-ACP_TE_C |
Resolved |
| fabG3 Rv2002 |
mtbc0_002129 |
3-alpha(or 20-beta)-hydroxysteroid dehydrogenase | SDR family oxidoreductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Family assigned |
| Rv2003c Rv2003c |
- |
hypothetical protein | Contains Methyltransf_11 (PF08241.19), Methyltransf_25 (PF13649.13), Methyltransf_23 (PF13489.13) domain(s); putative function inferred from the domain architecture. | Methyltransf_11 Methyltransf_25 Methyltransf_23 |
Family assigned |
| Rv2004c Rv2004c |
mtbc0_002132 |
hypothetical protein | AAA family ATPase. Pfam: Zeta_toxin (PF06414.19), AAA_33 (PF13671.13). | Zeta_toxin AAA_33 |
Family assigned |
| Rv2005c Rv2005c |
mtbc0_002133 |
universal stress protein | Universal stress protein. Pfam: Usp (PF00582.33). | Usp |
Resolved |
| otsB1 Rv2006 |
- |
trehalose-6-phosphate phosphatase OtsB | Trehalose-6-phosphate phosphatase OtsB. Pfam: Hydrolase (PF00702.33), Trehalose_PPase (PF02358.23), Glyco_hydro_65N (PF03636.22), Glyco_hydro_65m (PF03632.22), Glyco_hydro_65C (PF03633.21). | Hydrolase Trehalose_PPase Glyco_hydro_65N Glyco_hydro_65m Glyco_hydro_65C |
Resolved |
| fdxA Rv2007c |
mtbc0_002135 |
ferredoxin | Ferredoxin family protein. Pfam: Fer4 (PF00037.33). | Fer4 |
Family assigned |
| Rv2008c Rv2008c |
- |
hypothetical protein | Contains AAA_14 (PF13173.13), DUF4143 (PF13635.13) domain(s); putative function inferred from the domain architecture. | AAA_14 DUF4143 |
Family assigned |
| vapB15 Rv2009 |
- |
antitoxin VapB15 | Antitoxin VapB15. Pfam: VapB_antitoxin (PF09957.16). | VapB_antitoxin |
Resolved |
| vapC15 Rv2010 |
mtbc0_002138 |
ribonuclease VapC15 | PIN domain nuclease. Pfam: PIN (PF01850.28). | PIN |
Family assigned |
| Rv2011c Rv2011c |
mtbc0_002139 |
hypothetical protein | MarR family winged helix-turn-helix transcriptional regulator. Pfam: MarR_2 (PF12802.14). | MarR_2 |
Family assigned |
| Rv2012 Rv2012 |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 2hh8-assembly1_A Solution NMR structure of the ydfO protein from Escherichia col (prob 1.00, TM 0.74). Structure-based, putative. | DUF1398 |
Family assigned |
| Rv2015c Rv2015c |
mtbc0_002145 |
hypothetical protein | HNH endonuclease signature motif containing protein. Pfam: DUF222 (PF02720.23), HNH (PF01844.30). | DUF222 HNH |
Resolved |
| Rv2016 Rv2016 |
mtbc0_002146 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 2e2l-assembly1_E Helicobacter pylori formamidase AmiF contains a fine- (prob 0.13, TM 0.52). | Still unknown | |
| Rv2017 Rv2017 |
mtbc0_002147 |
transcriptional regulator | ImmA/IrrE family metallo-endopeptidase. Pfam: HTH_31 (PF13560.13), HTH_19 (PF12844.14), HTH_3 (PF01381.29), Peptidase_M78 (PF06114.20). | HTH_31 HTH_19 HTH_3 Peptidase_M78 |
Family assigned |
| Rv2018 Rv2018 |
mtbc0_002148 |
hypothetical protein | DUF433 domain-containing protein. Pfam: HTH_66 (PF21321.4), DUF433 (PF04255.21). | HTH_66 DUF433 |
Family assigned |
| Rv2019 Rv2019 |
mtbc0_002149 |
hypothetical protein | Contains PIN_10 (PF18478.8) domain(s); putative function inferred from the domain architecture. | PIN_10 |
Family assigned |
| Rv2020c Rv2020c |
|
Conserved hypothetical protein | site-specific DNA-methyltransferase (adenine-specific) activity | Type_ISP_C |
Family assigned |
| Rv2021c Rv2021c |
mtbc0_002151 |
transcriptional regulator | XRE family transcriptional regulator. Pfam: HTH_37 (PF13744.13), HTH_31 (PF13560.13), HTH_3 (PF01381.29). | HTH_37 HTH_31 HTH_3 |
Family assigned |
| Rv2022c Rv2022c |
mtbc0_002152 |
hypothetical protein | Type II toxin-antitoxin system RelE/ParE family toxin. Pfam: Gp49 (PF05973.21). | Gp49 |
Family assigned |
| Rv2023c Rv2023c |
mtbc0_002153 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2024c Rv2024c |
- |
hypothetical protein | Contains Mrr_cat (PF04471.19), Mrr_cat_2 (PF13156.13), ResIII (PF04851.22), DEAD (PF00270.36) domain(s); putative function inferred from the domain architecture. | Mrr_cat Mrr_cat_2 ResIII DEAD |
Family assigned |