Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv3769 Rv3769 |
mtbc0_003993 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv3770c Rv3770c |
mtbc0_003994 |
hypothetical protein | Polytopic integral membrane protein with 5 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | Family assigned | |
| Rv3771c Rv3771c |
mtbc0_003996 |
hypothetical protein | Transposase (eggNOG COG3677, IS-family transposase; COG category L). A mobile-element function, not a host-metabolic gene. | Family assigned | |
| hisC2 Rv3772 |
mtbc0_003999 |
histidinol-phosphate aminotransferase | Histidinol-phosphate transaminase. Pfam: Aminotran_1_2 (PF00155.28). | Aminotran_1_2 |
Resolved |
| Rv3773c Rv3773c |
mtbc0_004000 |
hypothetical protein | TIGR03086 family metal-binding protein. | Family assigned | |
| echA21 Rv3774 |
mtbc0_004001 |
enoyl-CoA hydratase EchA21 | Crotonase/enoyl-CoA hydratase family protein. Pfam: ECH_1 (PF00378.26), ECH_2 (PF16113.11). | ECH_1 ECH_2 |
Family assigned |
| lipE Rv3775 |
mtbc0_004002 |
lipase LipE | Lipase LipE. Pfam: Beta-lactamase (PF00144.30). | Beta-lactamase |
Resolved |
| Rv3776 Rv3776 |
- |
hypothetical protein | HNH endonuclease of the 13E12-repeat family (eggNOG COG1403, COG category V). RefSeq leaves it 'hypothetical protein'. HNH nuclease motif; target undetermined. | DUF222 |
Family assigned |
| Rv3777 Rv3777 |
- |
oxidoreductase | Oxidoreductase. Pfam: ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13). | ADH_N ADH_zinc_N ADH_zinc_N_2 |
Resolved |
| Rv3778c Rv3778c |
mtbc0_004006 |
aminotransferase | Cysteine desulfurase-like protein. Pfam: Aminotran_5 (PF00266.26). | Aminotran_5 |
Family assigned |
| Rv3779 Rv3779 |
mtbc0_004007 |
transmembrane protein | DUF6541 family protein. | DUF6541 |
Family assigned |
| bpa Rv3780 |
mtbc0_004008 |
hypothetical protein | Proteasome activator protein Bpa. Pfam: BPA (PF10759.15). | BPA |
Resolved |
| rfbE Rv3781 |
mtbc0_004009 |
O-antigen/lipopolysaccharide ABC transporter ATP-binding protein RfbE | ABC transporter ATP-binding protein. Pfam: ABC_tran (PF00005.34). | ABC_tran |
Family assigned |
| glfT1 Rv3782 |
- |
galactofuranosyl transferase GlfT | Galactofuranosyl transferase GlfT. Pfam: Glycos_transf_2 (PF00535.33). | Glycos_transf_2 |
Resolved |
| rfbD Rv3783 |
mtbc0_004011 |
O-antigen/lipopolysaccharide ABC transporter permease RfbD | ABC transporter permease. Pfam: ABC2_membrane (PF01061.30). | ABC2_membrane |
Family assigned |
| Rv3784 Rv3784 |
- |
dTDP-glucose 4,6-dehydratase | DTDP-glucose 4,6-dehydratase. Pfam: RmlD_sub_bind (PF04321.24), Epimerase (PF01370.28), Polysacc_synt_2 (PF02719.22), GDP_Man_Dehyd (PF16363.12), 3Beta_HSD (PF01073.26), NAD_binding_4 (PF07993.19), NAD_binding_10 (PF13460.13). | RmlD_sub_bind Epimerase Polysacc_synt_2 GDP_Man_Dehyd 3Beta_HSD NAD_binding_4 NAD_binding_10 |
Resolved |
| Rv3785 Rv3785 |
mtbc0_004013 |
hypothetical protein | Contains Rv3785_N (PF27209.1) domain(s); putative function inferred from the domain architecture. | Rv3785_N |
Family assigned |
| Rv3786c Rv3786c |
mtbc0_004014 |
hypothetical protein | Peptidoglycan DD-metalloendopeptidase family protein. Pfam: Peptidase_M23 (PF01551.30). | Peptidase_M23 |
Family assigned |
| Rv3787c Rv3787c |
mtbc0_004015 |
S-adenosyl-L-methionine-dependent methyltransferase | Class I SAM-dependent methyltransferase. Pfam: LCM (PF04072.21). | LCM |
Resolved |
| Rv3788 Rv3788 |
mtbc0_004016 |
hypothetical protein | GreA/GreB family elongation factor. Pfam: GreA_GreB (PF01272.26). | GreA_GreB |
Family assigned |
| Rv3789 Rv3789 |
mtbc0_004017 |
GtrA family protein | Arabinogalactan biosynthesis protein. Pfam: GtrA_DPMS_TM (PF04138.21). | GtrA_DPMS_TM |
Resolved |
| dprE1 Rv3790 |
mtbc0_004018 |
decaprenylphosphoryl-beta-D-ribose oxidase | Decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase DprE1. Pfam: FAD_binding_4 (PF01565.29), ALO (PF04030.20). | FAD_binding_4 ALO |
Resolved |
| dprE2 Rv3791 |
- |
decaprenylphosphoryl-D-2-keto erythropentose reductase | Decaprenylphosphoryl-D-2-keto erythropentose reductase. Pfam: adh_short (PF00106.32), KR (PF08659.17), adh_short_C2 (PF13561.13). | adh_short KR adh_short_C2 |
Resolved |
| aftA Rv3792 |
mtbc0_004020 |
arabinofuranosyltransferase | Galactan 5-O-arabinofuranosyltransferase. Pfam: AftA_N (PF12250.15), AftA_C (PF12249.14). | AftA_N AftA_C |
Resolved |
| embC Rv3793 |
mtbc0_004021 |
arabinosyltransferase C | Arabinosyltransferase EmbC. Pfam: Arabino_trans_N (PF17689.9), Arabinose_trans (PF04602.19), Arabino_trans_C (PF14896.13). | Arabino_trans_N Arabinose_trans Arabino_trans_C |
Resolved |
| embA Rv3794 |
mtbc0_004022 |
arabinosyltransferase A | Arabinosyltransferase EmbA. Pfam: Arabino_trans_N (PF17689.9), Arabinose_trans (PF04602.19), Arabino_trans_C (PF14896.13). | Arabino_trans_N Arabinose_trans Arabino_trans_C |
Resolved |
| embB Rv3795 |
mtbc0_004023 |
arabinosyltransferase B | Arabinosyltransferase EmbB. Pfam: Arabino_trans_N (PF17689.9), Arabinose_trans (PF04602.19), Arabino_trans_C (PF14896.13). | Arabino_trans_N Arabinose_trans Arabino_trans_C |
Resolved |
| Rv3796 Rv3796 |
- |
hypothetical protein | Contains Lactamase_B (PF00753.34), Anti-Pycsar_Apyc1 (PF23023.2), Lactamase_B_2 (PF12706.14) domain(s); putative function inferred from the domain architecture. | Lactamase_B Anti-Pycsar_Apyc1 Lactamase_B_2 |
Family assigned |
| fadE35 Rv3797 |
mtbc0_004025 |
acyl-CoA dehydrogenase FadE35 | DNA alkylation response protein. Pfam: AidB_N (PF18158.7), Acyl-CoA_dh_M (PF02770.25), Acyl-CoA_dh_1 (PF00441.30), Acyl-CoA_dh_2 (PF08028.17). | AidB_N Acyl-CoA_dh_M Acyl-CoA_dh_1 Acyl-CoA_dh_2 |
Resolved |
| Rv3798 Rv3798 |
- |
insertion sequence element IS1557 transposase | Insertion sequence element IS1557 transposase. Pfam: Zn_ribbon_ISL3 (PF14690.12), HTH_Tnp_ISL3 (PF13542.13), DDE_Tnp_ISL3 (PF01610.24). | Zn_ribbon_ISL3 HTH_Tnp_ISL3 DDE_Tnp_ISL3 |
Resolved |
| accD4 Rv3799c |
mtbc0_004027 |
propionyl-CoA carboxylase subunit beta AccD | Acyl-CoA carboxylase subunit beta. Pfam: Carboxyl_trans (PF01039.28), ACCA (PF03255.20). | Carboxyl_trans ACCA |
Family assigned |
| pks13 Rv3800c |
mtbc0_004028 |
polyketide synthase | Polyketide synthase Pks13. Pfam: PP-binding (PF00550.32), ketoacyl-synt (PF00109.33), Thiolase_N (PF00108.30), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12), Acyl_transf_1 (PF00698.27), Thioesterase (PF00975.27). | PP-binding ketoacyl-synt Thiolase_N Ketoacyl-synt_C KAsynt_C_assoc Acyl_transf_1 Thioesterase |
Resolved |
| fadD32 Rv3801c |
- |
long-chain-fatty-acid--AMP ligase FadD32 | Long-chain-fatty-acid--AMP ligase FadD32. Pfam: AMP-binding (PF00501.35). | AMP-binding |
Resolved |
| Rv3802c Rv3802c |
mtbc0_004030 |
membrane protein | Phospholipase. Pfam: Cutinase (PF01083.29), PE-PPE (PF08237.18). | Cutinase PE-PPE |
Resolved |
| fbpD Rv3803c |
- |
MPT51/MPB51 antigen | MPT51/MPB51 antigen. Pfam: Esterase (PF00756.27). | Esterase |
Resolved |
| fbpA Rv3804c |
mtbc0_004032 |
diacylglycerol acyltransferase/mycolyltransferase Ag85A | Diacylglycerol acyltransferase/mycolyltransferase Ag85A. Pfam: Esterase (PF00756.27). | Esterase |
Resolved |
| aftB Rv3805c |
- |
terminal beta-(1->2)-arabinofuranosyltransferase | Terminal beta-(1->2)-arabinofuranosyltransferase. Pfam: AftB_C (PF26371.1). | AftB_C |
Resolved |
| ubiA Rv3806c |
mtbc0_004034 |
decaprenyl-phosphate phosphoribosyltransferase | Decaprenyl-phosphate phosphoribosyltransferase. Pfam: UbiA (PF01040.24). | UbiA |
Resolved |
| Rv3807c Rv3807c |
- |
decaprenylphosphoryl-5-phosphoribose phosphatase | Decaprenylphosphoryl-5-phosphoribose phosphatase. Pfam: PAP2 (PF01569.28). | PAP2 |
Resolved |
| glfT2 Rv3808c |
mtbc0_004036 |
galactofuranosyl transferase GlfT | Galactofuranosyl transferase GlfT2. Pfam: Glft2_N (PF17994.8), Glyco_tranf_2_3 (PF13641.13), GlfT2_domain3 (PF19320.5). | Glft2_N Glyco_tranf_2_3 GlfT2_domain3 |
Resolved |
| glf Rv3809c |
mtbc0_004037 |
UDP-galactopyranose mutase | UDP-galactopyranose mutase. Pfam: NAD_binding_8 (PF13450.13), Amino_oxidase (PF01593.31), GLF (PF03275.20). | NAD_binding_8 Amino_oxidase GLF |
Resolved |
| pirG Rv3810 |
mtbc0_004038 |
cell surface protein | Exported repetitive protein. | Resolved | |
| Rv3811 Rv3811 |
- |
hypothetical protein | Contains Rv3811_N (PF27503.1), Amidase_2 (PF01510.31), LGFP (PF08310.18) domain(s); putative function inferred from the domain architecture. | Rv3811_N Amidase_2 LGFP |
Family assigned |
| PE_PGRS62 Rv3812 |
- |
PE-PGRS family protein PE_PGRS62 | PE-PGRS family protein PE_PGRS62. Pfam: PE (PF00934.26). | PE |
Family assigned |
| Rv3813c Rv3813c |
mtbc0_004042 |
hypothetical protein | Cof-type HAD-IIB family hydrolase. Pfam: Hydrolase_3 (PF08282.19), S6PP (PF05116.20). | Hydrolase_3 S6PP |
Family assigned |
| Rv3814c Rv3814c |
mtbc0_004043 |
acyltransferase | 1-acyl-sn-glycerol-3-phosphate acyltransferase. Pfam: Acyltransferase (PF01553.27). | Acyltransferase |
Resolved |
| Rv3815c Rv3815c |
mtbc0_004044 |
acyltransferase | Lysophospholipid acyltransferase family protein. Pfam: Acyltransferase (PF01553.27). | Acyltransferase |
Family assigned |
| Rv3816c Rv3816c |
mtbc0_004045 |
acyltransferase | 1-acyl-sn-glycerol-3-phosphate acyltransferase. Pfam: Acyltransferase (PF01553.27). | Acyltransferase |
Resolved |
| Rv3817 Rv3817 |
mtbc0_004046 |
phosphotransferase | Aminoglycoside 3'-phosphotransferase. Pfam: APH (PF01636.30). | APH |
Resolved |
| Rv3818 Rv3818 |
mtbc0_004047 |
hypothetical protein | MBL fold metallo-hydrolase. Pfam: Lactamase_B_3 (PF13483.13), SCP2_Rv3818 (PF25451.2), Rieske (PF00355.33). | Lactamase_B_3 SCP2_Rv3818 Rieske |
Resolved |