Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv2962c Rv2962c |
mtbc0_003145 |
PGL/p-HBAD biosynthesis rhamnosyltransferase | PGL/p-HBAD biosynthesis rhamnosyltransferase. Pfam: Glyco_tran_28_C (PF04101.23), UDPGT (PF00201.25), EryCIII-like_C (PF06722.19). | Glyco_tran_28_C UDPGT EryCIII-like_C |
Resolved |
| Rv2963 Rv2963 |
mtbc0_003146 |
integral membrane protein | Permease. Pfam: ArsP_1 (PF03773.20). | ArsP_1 |
Resolved |
| purU Rv2964 |
mtbc0_003147 |
formyltetrahydrofolate deformylase | Formyltetrahydrofolate deformylase. Pfam: ACT (PF01842.32), Formyl_trans_N (PF00551.25). | ACT Formyl_trans_N |
Resolved |
| kdtB Rv2965c |
mtbc0_003149 |
phosphopantetheine adenylyltransferase | Pantetheine-phosphate adenylyltransferase. Pfam: CTP_transf_like (PF01467.33), Citrate_ly_lig (PF08218.18). | CTP_transf_like Citrate_ly_lig |
Resolved |
| rsmD Rv2966c |
mtbc0_003150 |
methyltransferase | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. Pfam: Cons_hypoth95 (PF03602.22), MTS (PF05175.21). | Cons_hypoth95 MTS |
Resolved |
| pca Rv2967c |
mtbc0_003151 |
pyruvate carboxylase | Pyruvate carboxylase. Pfam: Biotin_carb_N (PF00289.29), CPSase_L_D2 (PF02786.23), Dala_Dala_lig_C (PF07478.19), Biotin_carb_C (PF02785.26), HMGL-like (PF00682.26), PYC_OADA (PF02436.24), Biotin_lipoyl (PF00364.29). | Biotin_carb_N CPSase_L_D2 Dala_Dala_lig_C Biotin_carb_C HMGL-like PYC_OADA Biotin_lipoyl |
Resolved |
| Rv2968c Rv2968c |
mtbc0_003152 |
integral membrane protein | Vitamin K epoxide reductase family protein. Pfam: VKOR (PF07884.20). | VKOR |
Family assigned |
| Rv2969c Rv2969c |
mtbc0_003153 |
hypothetical protein | Mycothiol-dependent reductase. Pfam: Thioredoxin_4 (PF13462.13). | Thioredoxin_4 |
Resolved |
| Rv2970A Rv2970A |
- |
hypothetical protein | Aldo-keto reductase (NADP) family ORF (eggNOG COG0656, EC 1.1.1.346; COG category S). Short ORF matching the AKR family at strong orthology (partial); substrate undetermined. | Family assigned | |
| lipN Rv2970c |
mtbc0_003154 |
lipase/esterase LipN | Lipase/esterase LipN. Pfam: BD-FAE (PF20434.6), Abhydrolase_3 (PF07859.20). | BD-FAE Abhydrolase_3 |
Resolved |
| Rv2971 Rv2971 |
mtbc0_003156 |
oxidoreductase | Aldo/keto reductase. Pfam: Aldo_ket_red (PF00248.28). | Aldo_ket_red |
Resolved |
| Rv2972c Rv2972c |
mtbc0_003157 |
hypothetical protein | HNH endonuclease family protein. Pfam: GmrSD_C (PF07510.17). | GmrSD_C |
Family assigned |
| recG Rv2973c |
mtbc0_003158 |
ATP-dependent DNA helicase RecG | ATP-dependent DNA helicase RecG. Pfam: RecG_wedge (PF17191.11), ResIII (PF04851.22), DEAD (PF00270.36), Helicase_C (PF00271.38). | RecG_wedge ResIII DEAD Helicase_C |
Resolved |
| Rv2974c Rv2974c |
- |
hypothetical protein | Contains Dak2 (PF02734.23), FakA-like_M (PF21645.4), FakA-like_C (PF13684.12) domain(s); putative function inferred from the domain architecture. | Dak2 FakA-like_M FakA-like_C |
Family assigned |
| Rv2975a Rv2975a |
- |
50S ribosomal protein L28 | 50S ribosomal protein L28. Pfam: Ribosomal_L28 (PF00830.25). | Ribosomal_L28 |
Resolved |
| Rv2975c Rv2975c |
- |
hypothetical protein | Dihydroxyacetone (glycerone) kinase, DhaK/DhaL-family subunit (eggNOG COG1461, EC 2.7.1.28/2.7.1.29/4.6.1.15). RefSeq leaves it 'hypothetical protein'. Small ORF matching the kinase subunit at strong orthology; partner subunit/operon undetermined. | Family assigned | |
| ung Rv2976c |
mtbc0_003161 |
uracil-DNA glycosylase | Uracil-DNA glycosylase. Pfam: UDG (PF03167.26). | UDG |
Resolved |
| thiL Rv2977c |
mtbc0_003162 |
thiamine-monophosphate kinase | Thiamine-phosphate kinase. Pfam: AIRS (PF00586.30), AIRS_C (PF02769.28). | AIRS AIRS_C |
Resolved |
| tnpB Rv2978c |
mtbc0_000636 |
transposase | IS607 family element RNA-guided endonuclease TnpB. Pfam: HTH_OrfB_IS605 (PF12323.15), OrfB_IS605 (PF01385.26), Cas12f1-like_TNB (PF07282.19). | HTH_OrfB_IS605 OrfB_IS605 Cas12f1-like_TNB |
Family assigned |
| Rv2979c Rv2979c |
mtbc0_003164 |
resolvase | IS607 family transposase. Pfam: Resolvase (PF00239.27). | Resolvase |
Family assigned |
| Rv2980 Rv2980 |
mtbc0_003165 |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF3515. Function unknown. Foldseek best (non-significant) hit: 5y39-assembly1_B Crystal structure of Ragulator complex (p18 76-145) (prob 0.38, TM 0.58). | DUF3515 |
Still unknown |
| ddlA Rv2981c |
mtbc0_003166 |
D-alanine--D-alanine ligase | D-alanine--D-alanine ligase DdlA. Pfam: Dala_Dala_lig_N (PF01820.28), Dala_Dala_lig_C (PF07478.19), ATP-grasp (PF02222.28). | Dala_Dala_lig_N Dala_Dala_lig_C ATP-grasp |
Resolved |
| gpdA2 Rv2982c |
mtbc0_003167 |
glycerol-3-phosphate dehydrogenase | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase. Pfam: F420_oxidored (PF03807.24), NAD_binding_2 (PF03446.22), NAD_Gly3P_dh_N (PF01210.30), ApbA (PF02558.23), NAD_Gly3P_dh_C (PF07479.20), GPD_NAD_C_bact (PF20618.4). | F420_oxidored NAD_binding_2 NAD_Gly3P_dh_N ApbA NAD_Gly3P_dh_C GPD_NAD_C_bact |
Resolved |
| cofC Rv2983 |
mtbc0_003168 |
2-phospho-L-lactate guanylyltransferase | 2-phospho-L-lactate guanylyltransferase. Pfam: CofC (PF01983.22), NTP_transf_3 (PF12804.14). | CofC NTP_transf_3 |
Resolved |
| ppk1 Rv2984 |
mtbc0_003169 |
polyphosphate kinase | RNA degradosome polyphosphate kinase. Pfam: PP_kinase_N (PF13089.12), PP_kinase (PF02503.23), PP_kinase_C_1 (PF17941.8), PP_kinase_C (PF13090.13), PLDc_2 (PF13091.13). | PP_kinase_N PP_kinase PP_kinase_C_1 PP_kinase_C PLDc_2 |
Resolved |
| mutT1 Rv2985 |
mtbc0_003170 |
8-oxo-dGTP diphosphatase | NUDIX hydrolase. Pfam: NUDIX (PF00293.35), His_Phos_1 (PF00300.28). | NUDIX His_Phos_1 |
Resolved |
| hupB Rv2986c |
mtbc0_003171 |
DNA-binding protein HU | DNA-binding protein HupB. Pfam: Bac_DNA_binding (PF00216.27). | Bac_DNA_binding |
Family assigned |
| leuD Rv2987c |
mtbc0_003172 |
3-isopropylmalate dehydratase small subunit | 3-isopropylmalate dehydratase small subunit. Pfam: Aconitase_C (PF00694.26). | Aconitase_C |
Family assigned |
| leuC Rv2988c |
mtbc0_003173 |
3-isopropylmalate dehydratase large subunit | 3-isopropylmalate dehydratase large subunit. Pfam: Aconitase (PF00330.26). | Aconitase |
Family assigned |
| Rv2989 Rv2989 |
mtbc0_003174 |
transcriptional regulator | IclR family transcriptional regulator. Pfam: HTH_IclR (PF09339.17), IclR_C (PF01614.25). | HTH_IclR IclR_C |
Family assigned |
| Rv2990c Rv2990c |
mtbc0_003175 |
hypothetical protein | Class I SAM-dependent methyltransferase. | Resolved | |
| Rv2991 Rv2991 |
mtbc0_003176 |
hypothetical protein | PPOX class F420-dependent oxidoreductase. Pfam: PNPOx_N (PF01243.28), Pyridox_ox_2 (PF12900.14). | PNPOx_N Pyridox_ox_2 |
Resolved |
| gltS Rv2992c |
- |
glutamate--tRNA ligase | Glutamate--tRNA ligase. Pfam: tRNA-synt_1c (PF00749.28), Anticodon_2 (PF19269.5). | tRNA-synt_1c Anticodon_2 |
Resolved |
| Rv2993c Rv2993c |
- |
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase. Pfam: Rv2993c-like_N (PF10370.15), FAA_hydrolase (PF01557.24). | Rv2993c-like_N FAA_hydrolase |
Resolved |
| Rv2994 Rv2994 |
- |
MFS-type transporter | MFS-type transporter. Pfam: MFS_1 (PF07690.22). | MFS_1 |
Resolved |
| leuB Rv2995c |
mtbc0_003182 |
3-isopropylmalate dehydrogenase | 3-isopropylmalate dehydrogenase. Pfam: Iso_dh (PF00180.26). | Iso_dh |
Resolved |
| serA1 Rv2996c |
- |
D-3-phosphoglycerate dehydrogenase | D-3-phosphoglycerate dehydrogenase. Pfam: 2-Hacid_dh (PF00389.37), 2-Hacid_dh_C (PF02826.26), NAD_binding_2 (PF03446.22), PGDH_inter (PF19304.5), ACT (PF01842.32). | 2-Hacid_dh 2-Hacid_dh_C NAD_binding_2 PGDH_inter ACT |
Resolved |
| Rv2997 Rv2997 |
mtbc0_003184 |
dehydrogenase | NAD(P)/FAD-dependent oxidoreductase. Pfam: Thi4 (PF01946.24), FAD_oxidored (PF12831.14), NAD_binding_8 (PF13450.13). | Thi4 FAD_oxidored NAD_binding_8 |
Resolved |
| Rv2998 Rv2998 |
mtbc0_003186 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| lppY Rv2999 |
mtbc0_003188 |
lipoprotein LppY | LysM-repeat peptidoglycan-binding protein (eggNOG COG1388, COG category M). LysM domain; cell-wall role undetermined. | DUF1529 |
Family assigned |
| Rv3000 Rv3000 |
mtbc0_003189 |
transmembrane protein | ABC transporter permease. Pfam: ABC_tran (PF00005.34), UPF0014 (PF03649.19). | ABC_tran UPF0014 |
Family assigned |
| ilvC Rv3001c |
mtbc0_003190 |
ketol-acid reductoisomerase | Ketol-acid reductoisomerase. Pfam: KARI_N (PF07991.19), 2-Hacid_dh_C (PF02826.26), NAD_binding_2 (PF03446.22), KARI_C (PF01450.26). | KARI_N 2-Hacid_dh_C NAD_binding_2 KARI_C |
Resolved |
| ilvN Rv3002c |
mtbc0_003191 |
acetolactate synthase small subunit | Acetolactate synthase small subunit. Pfam: ACT (PF01842.32), ACT_AHAS_ss (PF22629.3), ACT_5 (PF13710.13), ALS_ss_C (PF10369.16). | ACT ACT_AHAS_ss ACT_5 ALS_ss_C |
Family assigned |
| ilvB1 Rv3003c |
- |
acetolactate synthase large subunit IlvB | Acetolactate synthase large subunit IlvB. Pfam: TPP_enzyme_N (PF02776.24), TPP_enzyme_M (PF00205.29), TPP_enzyme_C (PF02775.27). | TPP_enzyme_N TPP_enzyme_M TPP_enzyme_C |
Family assigned |
| cfp6 Rv3004 |
- |
low molecular weight protein antigen 6 | Low molecular weight protein antigen 6. Pfam: bPH_6 (PF10756.16). | bPH_6 |
Resolved |
| Rv3005c Rv3005c |
mtbc0_003194 |
hypothetical protein | DoxX family protein. Pfam: DoxX (PF07681.18), MauE (PF07291.17). | DoxX MauE |
Family assigned |
| lppZ Rv3006 |
mtbc0_003195 |
lipoprotein LppZ | Sorbosone dehydrogenase family protein. Pfam: GSDH (PF07995.18). | GSDH |
Family assigned |
| Rv3007c Rv3007c |
mtbc0_003196 |
oxidoreductase | Flavin reductase family protein. Pfam: Flavin_Reduct (PF01613.25). | Flavin_Reduct |
Family assigned |
| Rv3008 Rv3008 |
mtbc0_003197 |
hypothetical protein | MgtC/SapB family protein. | Family assigned | |
| gatB Rv3009c |
mtbc0_003198 |
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB. Pfam: GatB_N (PF02934.21), GatB_Yqey (PF02637.24). | GatB_N GatB_Yqey |
Family assigned |