Genes
3974 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv1135A Rv1135A |
|
Possible acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase) | Possible acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase) | Thiolase_C |
Family assigned |
| PPE16 Rv1135c |
- |
PPE family protein PPE16 | PPE family protein PPE16. Pfam: PPE (PF00823.26), Pentapeptide_2 (PF01469.25). | PPE Pentapeptide_2 |
Family assigned |
| Rv1136 Rv1136 |
|
Possible enoyl-CoA hydratase | Involved in carnitine metabolism. | ECH_1 |
Family assigned |
| Rv1137c Rv1137c |
|
Hypothetical protein | — | Still unknown | |
| Rv1138a Rv1138a |
- |
hypothetical protein | Putative enoyl-CoA hydratase/isomerase (crotonase) family enzyme (eggNOG COG1024, EC 4.2.1.149; lipid-metabolism COG category I). Partial-length match to the family, exact acyl-CoA substrate undetermined, no catalytic site verified: a family-level assignment, not a demonstrated activity. | Family assigned | |
| Rv1138c Rv1138c |
mtbc0_001223 |
oxidoreductase | NAD(P)/FAD-dependent oxidoreductase. Pfam: FAD_binding_3 (PF01494.26), FAD_binding_2 (PF00890.31). | FAD_binding_3 FAD_binding_2 |
Resolved |
| Rv1139c Rv1139c |
mtbc0_001224 |
hypothetical protein | Isoprenylcysteine carboxyl methyltransferase family protein. Pfam: ICMT (PF04140.20), PEMT (PF04191.19). | ICMT PEMT |
Family assigned |
| Rv1140 Rv1140 |
- |
integral membrane protein | Integral membrane protein. Pfam: Rce1-like (PF02517.22). | Rce1-like |
Family assigned |
| echA11 Rv1141c |
mtbc0_001226 |
enoyl-CoA hydratase EchA11 | Enoyl-CoA hydratase. Pfam: ECH_1 (PF00378.26), ECH_2 (PF16113.11). | ECH_1 ECH_2 |
Resolved |
| echA10 Rv1142c |
mtbc0_001227 |
enoyl-CoA hydratase EchA10 | Enoyl-CoA hydratase. Pfam: ECH_1 (PF00378.26), ECH_2 (PF16113.11). | ECH_1 ECH_2 |
Resolved |
| mcr Rv1143 |
mtbc0_001228 |
alpha-methylacyl-CoA racemase | Alpha-methylacyl-CoA racemase. Pfam: CoA_transf_3 (PF02515.23). | CoA_transf_3 |
Resolved |
| Rv1144 Rv1144 |
mtbc0_001229 |
oxidoreductase | 3-hydroxyacyl-CoA dehydrogenase. Pfam: adh_short (PF00106.32), KR (PF08659.17), Epimerase (PF01370.28), adh_short_C2 (PF13561.13). | adh_short KR Epimerase adh_short_C2 |
Resolved |
| Rv1145 Rv1145 |
- |
transmembrane transport protein | Transmembrane transport protein. Pfam: MMPL (PF03176.22). | MMPL |
Resolved |
| Rv1146 Rv1146 |
- |
transmembrane transport protein | Transmembrane transport protein. Pfam: MMPL (PF03176.22). | MMPL |
Resolved |
| Rv1147 Rv1147 |
mtbc0_001232 |
hypothetical protein | Methyltransferase domain-containing protein. Pfam: Methyltransf_23 (PF13489.13), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19), Methyltransf_12 (PF08242.19). | Methyltransf_23 Methyltransf_25 Methyltransf_11 Methyltransf_12 |
Family assigned |
| Rv1148c Rv1148c |
- |
hypothetical protein | Contains DUF222 (PF02720.23), HNH (PF01844.30) domain(s); putative function inferred from the domain architecture. | DUF222 HNH |
Family assigned |
| Rv1149 Rv1149 |
- |
transposase | Transposase. | DUF4096 |
Resolved |
| cobB Rv1151c |
mtbc0_001237 |
NAD-dependent protein deacylase | NAD-dependent protein deacylase. Pfam: SIR2 (PF02146.24). | SIR2 |
Resolved |
| Rv1152 Rv1152 |
mtbc0_001238 |
transcriptional regulator | GntR family transcriptional regulator. Pfam: GntR (PF00392.28). | GntR |
Family assigned |
| omt Rv1153c |
mtbc0_001239 |
O-methyltransferase | Class I SAM-dependent methyltransferase. Pfam: LCM (PF04072.21). | LCM |
Resolved |
| Rv1154c Rv1154c |
- |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 2hiy-assembly1_B The structure of conserved bacterial protein SP0830 from Strept (prob 1.00, TM 0.79). Structure-based, putative. | DUF1697 |
Family assigned |
| Rv1155 Rv1155 |
mtbc0_001241 |
pyridoxine/pyridoxamine 5'-phosphate oxidase | PPOX class F420-dependent oxidoreductase. Pfam: PNPOx_N (PF01243.28). | PNPOx_N |
Resolved |
| Rv1155a Rv1155a |
- |
hypothetical protein | Conserved hypothetical protein; DUF domain(s) DUF5302. Function unknown. | DUF5302 |
Still unknown |
| Rv1156 Rv1156 |
mtbc0_001243 |
hypothetical protein | HhH-GPD-type base excision DNA repair protein. Pfam: HhH-GPD (PF00730.32). | HhH-GPD |
Resolved |
| Rv1157c Rv1157c |
mtbc0_001245 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 8glv-assembly1_Gs 96-nm repeat unit of doublet microtubules from Chlam (prob 0.04, TM 0.08). | Still unknown | |
| Rv1158c Rv1158c |
mtbc0_001246 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| pimE Rv1159 |
mtbc0_001247 |
polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol pentamannoside mannosyltransferase | Mannosyltransferase. Pfam: GT87 (PF09594.17). | GT87 |
Resolved |
| Rv1159A Rv1159A |
- |
4a-hydroxytetrahydrobiopterin dehydratase | 4a-hydroxytetrahydrobiopterin dehydratase. Pfam: Pterin_4a (PF01329.25). | Pterin_4a |
Resolved |
| mutT2 Rv1160 |
mtbc0_001249 |
8-oxo-dGTP diphosphatase | 8-oxo-dGTP diphosphatase MutT. Pfam: NUDIX (PF00293.35). | NUDIX |
Resolved |
| narG Rv1161 |
mtbc0_001250 |
nitrate reductase subunit alpha | Nitrate reductase subunit alpha. Pfam: Molybdopterin (PF00384.28), NarG_dom_V (PF28599.1), Molydop_binding (PF01568.28). | Molybdopterin NarG_dom_V Molydop_binding |
Family assigned |
| narH Rv1162 |
- |
nitrate reductase subunit beta | Nitrate reductase subunit beta. Pfam: Fer4_11 (PF13247.12), Fer4_10 (PF13237.12), Nitr_red_bet_C (PF14711.12). | Fer4_11 Fer4_10 Nitr_red_bet_C |
Family assigned |
| narJ Rv1163 |
- |
nitrate reductase subunit delta | Nitrate reductase subunit delta. Pfam: Nitrate_red_del (PF02613.21). | Nitrate_red_del |
Family assigned |
| narI Rv1164 |
mtbc0_001253 |
nitrate reductase subunit gamma | Respiratory nitrate reductase subunit gamma. Pfam: Nitrate_red_gam (PF02665.20). | Nitrate_red_gam |
Family assigned |
| typA Rv1165 |
mtbc0_001254 |
GTP-binding translation elongation factor | Translational GTPase TypA. Pfam: GTP_EFTU (PF00009.34), EF-G_D2 (PF22042.3), GTP_EFTU_D2 (PF03144.32), EFG_C (PF00679.31), BipA_C (PF21018.3). | GTP_EFTU EF-G_D2 GTP_EFTU_D2 EFG_C BipA_C |
Resolved |
| lpqW Rv1166 |
mtbc0_001255 |
monoacyl phosphatidylinositol tetramannoside-binding protein LpqW | Lipoarabinomannan biosynthesis protein LpqW. Pfam: SBP_bac_5 (PF00496.28). | SBP_bac_5 |
Resolved |
| Rv1167c Rv1167c |
mtbc0_001256 |
transcriptional regulator | TetR/AcrR family transcriptional regulator. Pfam: TetR_N (PF00440.30), TetR_C_11 (PF16859.11). | TetR_N TetR_C_11 |
Family assigned |
| PPE17 Rv1168c |
- |
PPE family protein PPE17 | PPE family protein PPE17. Pfam: PPE (PF00823.26), EspB_PPE (PF21856.3), PPE-SVP (PF12484.14). | PPE EspB_PPE PPE-SVP |
Family assigned |
| lipX Rv1169c |
- |
lipase LipX | Lipase LipX. Pfam: PE (PF00934.26). | PE |
Resolved |
| mshB Rv1170 |
mtbc0_001259 |
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase | N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase. Pfam: PIG-L (PF02585.23). | PIG-L |
Resolved |
| Rv1171 Rv1171 |
mtbc0_001260 |
hypothetical protein | Polytopic integral membrane protein with 4 predicted transmembrane helices (DeepTMHMM). RefSeq leaves it 'hypothetical protein'. A topological feature consistent with a membrane transporter/permease or membrane-embedded enzyme; the transported substrate and molecular function are undetermined. | Family assigned | |
| PE12 Rv1172c |
- |
PE family protein PE12 | PE family protein PE12. Pfam: PE (PF00934.26). | PE |
Family assigned |
| fbiC Rv1173 |
mtbc0_001262 |
FO synthase | Bifunctional FO biosynthesis protein CofGH. Pfam: Radical_SAM (PF04055.28), CofH_C (PF19288.5). | Radical_SAM CofH_C |
Resolved |
| TB8.4 Rv1174c |
mtbc0_001263 |
low molecular weight T-cell antigen | Hemophore-related protein. | Resolved | |
| fadH Rv1175c |
mtbc0_001264 |
NADPH dependent 2,4-dienoyl-CoA reductase FadH | NADPH-dependent 2%2C4-dienoyl-CoA reductase. Pfam: Oxidored_FMN (PF00724.27), Pyr_redox_2 (PF07992.21), Pyr_redox (PF00070.34), FAD_oxidored (PF12831.14), DAO (PF01266.31), FAD_binding_2 (PF00890.31), NAD_binding_8 (PF13450.13), Amino_oxidase (PF01593.31). | Oxidored_FMN Pyr_redox_2 Pyr_redox FAD_oxidored DAO FAD_binding_2 NAD_binding_8 Amino_oxidase |
Resolved |
| Rv1176c Rv1176c |
mtbc0_001265 |
hypothetical protein | PadR family transcriptional regulator. Pfam: PadR (PF03551.21), Vir_act_alpha_C (PF10400.16). | PadR Vir_act_alpha_C |
Family assigned |
| fdxC Rv1177 |
mtbc0_001266 |
ferredoxin FdxC | Ferredoxin family protein. Pfam: Fer4 (PF00037.33). | Fer4 |
Family assigned |
| dapC Rv1178 |
mtbc0_001267 |
aminotransferase | Succinyldiaminopimelate transaminase. Pfam: Aminotran_1_2 (PF00155.28). | Aminotran_1_2 |
Resolved |
| Rv1179c Rv1179c |
mtbc0_001268 |
hypothetical protein | DEAD/DEAH box helicase family protein. Pfam: ResIII (PF04851.22). | ResIII |
Family assigned |
| pks3 Rv1180 |
- |
polyketide beta-ketoacyl synthase | Polyketide beta-ketoacyl synthase. Pfam: ketoacyl-synt (PF00109.33), Thiolase_N (PF00108.30), Ketoacyl-synt_C (PF02801.29), KAsynt_C_assoc (PF16197.12). | ketoacyl-synt Thiolase_N Ketoacyl-synt_C KAsynt_C_assoc |
Resolved |
| pks4 Rv1181 |
- |
polyketide beta-ketoacyl synthase | Polyketide beta-ketoacyl synthase. Pfam: Acyl_transf_1 (PF00698.27), PKS_DH_N (PF21089.4), PS-DH (PF14765.13), SpnB_Rossmann (PF22953.4), ADH_N (PF08240.18), ADH_zinc_N (PF00107.33), ADH_zinc_N_2 (PF13602.13), KR (PF08659.17), adh_short (PF00106.32), PP-binding (PF00550.32). | Acyl_transf_1 PKS_DH_N PS-DH SpnB_Rossmann ADH_N ADH_zinc_N ADH_zinc_N_2 KR adh_short PP-binding |
Resolved |