Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| rpsT Rv2412 |
mtbc0_002568 |
30S ribosomal protein S20 | 30S ribosomal protein S20. Pfam: Ribosomal_S20p (PF01649.24). | Ribosomal_S20p |
Resolved |
| Rv2413c Rv2413c |
mtbc0_002569 |
hypothetical protein | DNA polymerase III subunit delta. Pfam: DNA_pol3_delta_C (PF21694.3). | DNA_pol3_delta_C |
Family assigned |
| Rv2414c Rv2414c |
mtbc0_002570 |
hypothetical protein | ComEC/Rec2 family competence protein. Pfam: Competence (PF03772.22). | Competence |
Family assigned |
| Rv2415c Rv2415c |
mtbc0_002571 |
hypothetical protein | ComEA family DNA-binding protein. Pfam: SLBB (PF10531.16), HHH_3 (PF12836.14), HHH (PF00633.30). | SLBB HHH_3 HHH |
Family assigned |
| eis Rv2416c |
- |
enhanced intracellular survival protein | Enhanced intracellular survival protein. Pfam: Acetyltransf_9 (PF13527.14), Acetyltransf_17 (PF17668.8), SCP2_2 (PF13530.12). | Acetyltransf_9 Acetyltransf_17 SCP2_2 |
Resolved |
| Rv2417c Rv2417c |
mtbc0_002573 |
DegV domain-containing protein | DegV family protein. Pfam: DegV (PF02645.22). | DegV |
Family assigned |
| octT Rv2418c |
mtbc0_002574 |
hypothetical protein | Diglucosylglycerate octanoyltransferase. | Resolved | |
| gpgP Rv2419c |
mtbc0_002575 |
glucosyl-3-phosphoglycerate phosphatase | Glucosyl-3-phosphoglycerate phosphatase. Pfam: His_Phos_1 (PF00300.28). | His_Phos_1 |
Resolved |
| rsfS Rv2420c |
mtbc0_002576 |
hypothetical protein | Ribosome silencing factor. Pfam: RsfS (PF02410.22). | RsfS |
Resolved |
| nadD Rv2421c |
- |
nicotinate-nucleotide adenylyltransferase | Nicotinate-nucleotide adenylyltransferase. Pfam: CTP_transf_like (PF01467.33). | CTP_transf_like |
Resolved |
| Rv2422 Rv2422 |
mtbc0_002579 |
hypothetical protein | Predicted toxin of a type II toxin-antitoxin (TA) system (eggNOG COG1848). RefSeq leaves it 'hypothetical protein'. Note: the Rv2421c-Rv2422 region also harbours a cryptic beta-lactam-binding ORF (Kumar 2017); the eggNOG orthology points to a TA-toxin fold for Rv2422 itself. Family-level; the cognate antitoxin and activity are undetermined. | Family assigned | |
| Rv2423 Rv2423 |
mtbc0_002580 |
hypothetical protein | Class I SAM-dependent methyltransferase. Pfam: MTS (PF05175.21), Methyltransf_23 (PF13489.13), TehB (PF03848.21), Methyltransf_25 (PF13649.13), Methyltransf_11 (PF08241.19). | MTS Methyltransf_23 TehB Methyltransf_25 Methyltransf_11 |
Resolved |
| Rv2424c Rv2424c |
- |
transposase | Transposase. Pfam: Transposase_20 (PF02371.23). | Transposase_20 |
Resolved |
| Rv2425c Rv2425c |
mtbc0_002582 |
hypothetical protein | VWA domain-containing protein. Pfam: VWA_CoxE (PF05762.21). | VWA_CoxE |
Family assigned |
| Rv2426c Rv2426c |
mtbc0_002583 |
hypothetical protein | MoxR family ATPase. Pfam: AAA_5 (PF07728.21), AAA (PF00004.36), AAA_2 (PF07724.21). | AAA_5 AAA AAA_2 |
Family assigned |
| proA Rv2427c |
mtbc0_002584 |
gamma-glutamyl phosphate reductase | Glutamate-5-semialdehyde dehydrogenase. Pfam: Aldedh (PF00171.28). | Aldedh |
Resolved |
| ahpC Rv2428 |
mtbc0_002586 |
alkyl hydroperoxide reductase subunit AhpC | Peroxiredoxin AhpC. Pfam: AhpC-TSA (PF00578.28), Redoxin (PF08534.17). | AhpC-TSA Redoxin |
Resolved |
| ahpD Rv2429 |
mtbc0_002587 |
alkyl hydroperoxide reductase AphD | Alkyl hydroperoxide reductase. Pfam: CMD (PF02627.26). | CMD |
Resolved |
| PPE41 Rv2430c |
- |
PPE family protein PPE41 | PPE family protein PPE41. Pfam: PPE (PF00823.26). | PPE |
Family assigned |
| PE25 Rv2431c |
- |
PE family protein PE25 | PE family protein PE25. Pfam: PE (PF00934.26). | PE |
Family assigned |
| Rv2432c Rv2432c |
mtbc0_002590 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 3e90-assembly3_C West Nile vi rus NS2B-NS3protease in complexed with i (prob 0.03, TM 0.44). | Still unknown | |
| nrtS Rv2433c |
mtbc0_002591 |
hypothetical protein | Nitrate/nitrite transporter NrtS. | Resolved | |
| Rv2434c Rv2434c |
mtbc0_002592 |
transmembrane protein | Mechanosensitive ion channel. Pfam: MS_channel_1st (PF21088.3), MS_channel_2nd (PF00924.25), MS_channel_3rd (PF21082.3), cNMP_binding (PF00027.36). | MS_channel_1st MS_channel_2nd MS_channel_3rd cNMP_binding |
Resolved |
| Rv2435c Rv2435c |
mtbc0_002593 |
cyclase | Adenylate/guanylate cyclase domain-containing protein. Pfam: HAMP (PF00672.31), Guanylate_cyc (PF00211.26). | HAMP Guanylate_cyc |
Family assigned |
| rbsK Rv2436 |
mtbc0_002594 |
ribokinase RbsK | Ribokinase RbsK. Pfam: PfkB (PF00294.30). | PfkB |
Resolved |
| Rv2437 Rv2437 |
mtbc0_002595 |
transmembrane protein | Isoprenylcysteine carboxylmethyltransferase family protein. Pfam: PEMT (PF04191.19), ICMT (PF04140.20). | PEMT ICMT |
Family assigned |
| Rv2438A Rv2438A |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| nadE Rv2438c |
mtbc0_002596 |
glutamine-dependent NAD(+) synthetase | NAD(+) synthase. Pfam: CN_hydrolase (PF00795.28), NAD_synthase (PF02540.24). | CN_hydrolase NAD_synthase |
Resolved |
| proB Rv2439c |
mtbc0_002598 |
glutamate 5-kinase protein | Glutamate 5-kinase. Pfam: AA_kinase (PF00696.34), PUA (PF01472.27). | AA_kinase PUA |
Resolved |
| obg Rv2440c |
mtbc0_002599 |
GTPase Obg | GTPase ObgE. Pfam: GTP1_OBG (PF01018.29), MMR_HSR1 (PF01926.30), FeoB_N (PF02421.25), DUF1967 (PF09269.17). | GTP1_OBG MMR_HSR1 FeoB_N DUF1967 |
Resolved |
| rpmA Rv2441c |
mtbc0_002600 |
50S ribosomal protein L27 | 50S ribosomal protein L27. Pfam: Ribosomal_L27 (PF01016.25). | Ribosomal_L27 |
Resolved |
| rplU Rv2442c |
mtbc0_002601 |
50S ribosomal protein L21 | 50S ribosomal protein L21. Pfam: Ribosomal_L21p (PF00829.27). | Ribosomal_L21p |
Resolved |
| dctA Rv2443 |
mtbc0_002602 |
C4-dicarboxylate-transport transmembrane protein DctA | Cation:dicarboxylase symporter family transporter. Pfam: SDF (PF00375.24). | SDF |
Family assigned |
| rne Rv2444c |
mtbc0_002603 |
ribonuclease E | Rne/Rng family ribonuclease. Pfam: RNase_E_G (PF10150.15). | RNase_E_G |
Family assigned |
| ndkA Rv2445c |
mtbc0_002604 |
nucleoside diphosphate kinase | Nucleoside-diphosphate kinase. Pfam: NDK (PF00334.25). | NDK |
Resolved |
| Rv2446c Rv2446c |
mtbc0_002605 |
integral membrane protein | Conserved hypothetical protein; DUF domain(s) DUF4233. Function unknown. | DUF4233 |
Still unknown |
| folC Rv2447c |
mtbc0_002606 |
folylpolyglutamate synthase FolC | Bifunctional tetrahydrofolate synthase/dihydrofolate synthase. Pfam: Mur_ligase_M (PF08245.19), Mur_ligase_C (PF02875.27). | Mur_ligase_M Mur_ligase_C |
Resolved |
| valS Rv2448c |
- |
valine--tRNA ligase | Valine--tRNA ligase. Pfam: tRNA-synt_1 (PF00133.29), tRNA-synt_1_2 (PF13603.13), tRNA-synt_1g (PF09334.18), Anticodon_1 (PF08264.20), Val_tRNA-synt_C (PF10458.15). | tRNA-synt_1 tRNA-synt_1_2 tRNA-synt_1g Anticodon_1 Val_tRNA-synt_C |
Resolved |
| Rv2449c Rv2449c |
mtbc0_002608 |
trans-acting enoyl reductase | Trans-acting enoyl reductase family protein. Pfam: Sacchrp_dh_NADP (PF03435.25). | Sacchrp_dh_NADP |
Family assigned |
| rpfE Rv2450c |
mtbc0_002609 |
resuscitation-promoting factor RpfE | Resuscitation-promoting factor protein RpfE. Pfam: Transglycosylas (PF06737.20). | Transglycosylas |
Resolved |
| Rv2451 Rv2451 |
mtbc0_002610 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2452c Rv2452c |
mtbc0_002611 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| mobA Rv2453c |
mtbc0_002612 |
molybdenum cofactor guanylyltransferase | Molybdenum cofactor guanylyltransferase. Pfam: NTP_transf_3 (PF12804.14). | NTP_transf_3 |
Resolved |
| Rv2454c Rv2454c |
mtbc0_002613 |
2-oxoglutarate oxidoreductase subunit KorB | 2-oxoacid:ferredoxin oxidoreductase subunit beta. Pfam: TPP_enzyme_C (PF02775.27). | TPP_enzyme_C |
Family assigned |
| Rv2455c Rv2455c |
mtbc0_002614 |
2-oxoglutarate oxidoreductase subunit KorA | 2-oxoacid:acceptor oxidoreductase subunit alpha. Pfam: POR (PF01558.26), POR_N (PF01855.25), PFOR_II (PF17147.10). | POR POR_N PFOR_II |
Family assigned |
| Rv2456c Rv2456c |
mtbc0_002615 |
MFS-type transporter | MFS transporter. Pfam: MFS_1 (PF07690.22), MFS_1_like (PF12832.14). | MFS_1 MFS_1_like |
Resolved |
| clpX Rv2457c |
mtbc0_002616 |
ATP-dependent CLP protease ATP-binding subunit ClpX | ATP-dependent Clp protease ATP-binding subunit ClpX. Pfam: zf-C4_ClpX (PF06689.20), AAA_2 (PF07724.21), AAA_5 (PF07728.21), AAA (PF00004.36), ClpB_D2-small (PF10431.16). | zf-C4_ClpX AAA_2 AAA_5 AAA ClpB_D2-small |
Family assigned |
| mmuM Rv2458 |
mtbc0_002617 |
homocysteine S-methyltransferase MmuM | Homocysteine S-methyltransferase. Pfam: S-methyl_trans (PF02574.23). | S-methyl_trans |
Resolved |
| jefA Rv2459 |
mtbc0_002618 |
MFS-type transporter | Multidrug efflux pump JefA. Pfam: MFS_1 (PF07690.22), Sugar_tr (PF00083.31). | MFS_1 Sugar_tr |
Resolved |
| clpP2 Rv2460c |
mtbc0_002619 |
ATP-dependent CLP protease proteolytic subunit 2 | ATP-dependent CLP protease proteolytic subunit ClpP2. Pfam: CLP_protease (PF00574.29). | CLP_protease |
Family assigned |