Genes
3906 genes matched.
| Gene | MTBC0 | Legacy (H37Rv) | MTBC0 PGAP / revised | Pfam | Verdict |
|---|---|---|---|---|---|
| Rv2366c Rv2366c |
mtbc0_002518 |
transmembrane protein | Hemolysin family protein. Pfam: CNNM (PF01595.26), CBS (PF00571.34), CorC_HlyC (PF03471.23). | CNNM CBS CorC_HlyC |
Family assigned |
| Rv2367c Rv2367c |
- |
endoribonuclease | Endoribonuclease. Pfam: YbeY (PF02130.25). | YbeY |
Resolved |
| phoH1 Rv2368c |
- |
phosphate starvation-inducible protein PhoH | Phosphate starvation-inducible protein PhoH. Pfam: PhoH (PF02562.23), AAA_30 (PF13604.13), AAA_19 (PF13245.13). | PhoH AAA_30 AAA_19 |
Resolved |
| Rv2369c Rv2369c |
mtbc0_002521 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2370c Rv2370c |
mtbc0_002522 |
hypothetical protein | PucR family transcriptional regulator. Pfam: GGDEF_2 (PF17853.7), HTH_30 (PF13556.13). | GGDEF_2 HTH_30 |
Family assigned |
| PE_PGRS40 Rv2371 |
- |
PE-PGRS family protein PE_PGRS40 | PE-PGRS family protein PE_PGRS40. Pfam: PE (PF00934.26). | PE |
Family assigned |
| Rv2372c Rv2372c |
mtbc0_002524 |
rRNA small subunit methyltransferase E | 16S rRNA (uracil(1498)-N(3))-methyltransferase. Pfam: PUA_4 (PF20260.5), Methyltrans_RNA (PF04452.20). | PUA_4 Methyltrans_RNA |
Resolved |
| dnaJ2 Rv2373c |
mtbc0_002525 |
chaperone protein DnaJ | Molecular chaperone DnaJ. Pfam: DnaJ (PF00226.37), DnaJ_C (PF01556.24), DnaJ_CXXCXGXG (PF00684.26). | DnaJ DnaJ_C DnaJ_CXXCXGXG |
Resolved |
| hrcA Rv2374c |
mtbc0_002526 |
heat-inducible transcription repressor HrcA | Heat-inducible transcriptional repressor HrcA. Pfam: HrcA (PF01628.28). | HrcA |
Resolved |
| Rv2375 Rv2375 |
mtbc0_002527 |
hypothetical protein | Type II toxin-antitoxin system VapB family antitoxin. Pfam: VapB (PF23719.2). | VapB |
Family assigned |
| cfp2 Rv2376c |
mtbc0_002528 |
low molecular weight antigen MTB12 | Low molecular weight antigen MTB12. Pfam: Mtb12_C (PF26580.1). | Mtb12_C |
Resolved |
| mbtH Rv2377c |
mtbc0_002529 |
hypothetical protein | Mycobactin NRPS accessory protein MbtH. Pfam: MbtH (PF03621.19). | MbtH |
Resolved |
| mbtG Rv2378c |
mtbc0_002530 |
L-lysine N6-monooxygenase | NADPH-dependent L-lysine N(6)-monooxygenase MbtG. Pfam: Lys_Orn_oxgnase (PF13434.13). | Lys_Orn_oxgnase |
Resolved |
| mbtF Rv2379c |
- |
peptide synthetase | Peptide synthetase. Pfam: Condensation (PF00668.26), AMP-binding (PF00501.35), AMP-binding_C (PF13193.13), PP-binding (PF00550.32). | Condensation AMP-binding AMP-binding_C PP-binding |
Resolved |
| mbtE Rv2380c |
- |
peptide synthetase | Peptide synthetase. Pfam: AMP-binding (PF00501.35), AMP-binding_C (PF13193.13), PP-binding (PF00550.32), Condensation (PF00668.26). | AMP-binding AMP-binding_C PP-binding Condensation |
Resolved |
| mbtD Rv2381c |
mtbc0_002533 |
polyketide synthetase | Mycobactin polyketide synthase MbtD. Pfam: Acyl_transf_1 (PF00698.27), KR (PF08659.17), adh_short (PF00106.32), Epimerase (PF01370.28), PP-binding (PF00550.32). | Acyl_transf_1 KR adh_short Epimerase PP-binding |
Resolved |
| mbtC Rv2382c |
mtbc0_002534 |
polyketide synthetase | Polyketide synthetase MbtC. Pfam: ketoacyl-synt (PF00109.33), Thiolase_N (PF00108.30), Ketoacyl-synt_C (PF02801.29). | ketoacyl-synt Thiolase_N Ketoacyl-synt_C |
Resolved |
| mbtB Rv2383c |
mtbc0_002535 |
phenyloxazoline synthase | Phenyloxazoline synthase MbtB. Pfam: Condensation (PF00668.26), AMP-binding (PF00501.35), AMP-binding_C (PF13193.13), PP-binding (PF00550.32), Thioesterase (PF00975.27). | Condensation AMP-binding AMP-binding_C PP-binding Thioesterase |
Resolved |
| mbtA Rv2384 |
mtbc0_002536 |
2,3-dihydroxybenzoate-AMP ligase | Bifunctional salicyl-AMP ligase/salicyl-S-ArCP synthetase MbtA. Pfam: AMP-binding (PF00501.35), AMP-binding_C (PF13193.13). | AMP-binding AMP-binding_C |
Resolved |
| mbtJ Rv2385 |
- |
acetyl hydrolase | Acetyl hydrolase. Pfam: BD-FAE (PF20434.6), Abhydrolase_3 (PF07859.20). | BD-FAE Abhydrolase_3 |
Resolved |
| Rv2386a Rv2386a |
- |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. Foldseek best (non-significant) hit: 1y96-assembly2_D crystal structure of the Gemin6/Gemin7 heterodimer fr (prob 0.98, TM 0.69). | Still unknown | |
| mbtI Rv2386c |
- |
salicylate synthase | Salicylate synthase. Pfam: Chorismate_bind (PF00425.25). | Chorismate_bind |
Resolved |
| Rv2387 Rv2387 |
mtbc0_002540 |
hypothetical protein | Sodium-dependent bicarbonate transport family permease. Pfam: Sbt_1 (PF05982.18). | Sbt_1 |
Family assigned |
| hemN Rv2388c |
- |
oxygen-independent coproporphyrinogen III oxidase | Oxygen-independent coproporphyrinogen III oxidase. Pfam: Radical_SAM (PF04055.28). | Radical_SAM |
Resolved |
| rpfD Rv2389c |
mtbc0_002542 |
resuscitation-promoting factor RpfD | Resuscitation-promoting factor protein RpfD. Pfam: Transglycosylas (PF06737.20). | Transglycosylas |
Resolved |
| Rv2390c Rv2390c |
mtbc0_002543 |
hypothetical protein | No Pfam domain above threshold; Foldseek indicates a fold similar to 8rta-assembly1_G Arches-protomer complex full-length structure (TrwJ/VirB8) from (prob 1.00, TM 0.65). Structure-based, putative. | Family assigned | |
| sirA Rv2391 |
- |
sulfite reductase | Sulfite reductase. Pfam: NIR_SIR_ferr (PF03460.23), NIR_SIR (PF01077.28). | NIR_SIR_ferr NIR_SIR |
Resolved |
| cysH Rv2392 |
mtbc0_002545 |
phosphoadenosine phosphosulfate reductase | Phosphoadenylyl-sulfate reductase. Pfam: PAPS_reduct (PF01507.26). | PAPS_reduct |
Resolved |
| che1 Rv2393 |
- |
ferrochelatase | Ferrochelatase. Pfam: CbiX (PF01903.23). | CbiX |
Resolved |
| ggtB Rv2394 |
mtbc0_002547 |
gamma-glutamyltranspeptidase precursor GgtB | Gamma-glutamyltransferase family protein. Pfam: G_glu_transpept (PF01019.28). | G_glu_transpept |
Family assigned |
| Rv2395 Rv2395 |
mtbc0_002548 |
integral membrane protein | Oligopeptide transporter%2C OPT family. Pfam: OPT (PF03169.21). | OPT |
Family assigned |
| aprA Rv2395A |
- |
acid and phagosome regulated protein AprA | Acid and phagosome regulated protein AprA. | Resolved | |
| aprB Rv2395B |
- |
acid and phagosome regulated protein AprB | Acid and phagosome regulated protein AprB. | Resolved | |
| PE_PGRS41 Rv2396 |
- |
acid and phagosome regulated protein AprC | Acid and phagosome regulated protein AprC. Pfam: PE (PF00934.26). | PE |
Resolved |
| cysA1 Rv2397c |
- |
sulfate ABC transporter ATP-binding protein CysA | Sulfate ABC transporter ATP-binding protein CysA. Pfam: ABC_tran (PF00005.34), TOBE_2 (PF08402.17), TOBE_3 (PF12857.14), TOBE (PF03459.24). | ABC_tran TOBE_2 TOBE_3 TOBE |
Family assigned |
| cysW Rv2398c |
mtbc0_002553 |
sulfate ABC transporter permease CysW | Sulfate ABC transporter permease subunit CysW. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| cysT Rv2399c |
mtbc0_002554 |
sulfate ABC transporter permease CysT | Sulfate ABC transporter permease subunit CysT. Pfam: BPD_transp_1 (PF00528.28). | BPD_transp_1 |
Family assigned |
| subI Rv2400c |
mtbc0_002555 |
sulfate ABC transporter substrate-binding lipoprotein SubI | Sulfate ABC transporter substrate-binding protein. Pfam: SBP_bac_11 (PF13531.12), SBP_bac_1 (PF01547.31), SBP_bac_8 (PF13416.12). | SBP_bac_11 SBP_bac_1 SBP_bac_8 |
Family assigned |
| Rv2401 Rv2401 |
mtbc0_002556 |
hypothetical protein | Conserved hypothetical protein; no recognised domain. Function unknown. | Still unknown | |
| Rv2401A Rv2401A |
- |
membrane protein | Membrane protein. | Family assigned | |
| Rv2402 Rv2402 |
- |
trehalase | Trehalase. Pfam: TREH_N (PF19291.5), Glyco_hydro_15 (PF00723.28). | TREH_N Glyco_hydro_15 |
Resolved |
| lppR Rv2403c |
mtbc0_002559 |
lipoprotein LppR | Sensor domain-containing protein. Pfam: PknH_C (PF14032.13). | PknH_C |
Family assigned |
| lepA Rv2404c |
mtbc0_002560 |
GTP-binding protein LepA | Translation elongation factor 4. Pfam: GTP_EFTU (PF00009.34), GTP_EFTU_D2 (PF03144.32), EFG_C (PF00679.31), LepA_C (PF06421.18). | GTP_EFTU GTP_EFTU_D2 EFG_C LepA_C |
Resolved |
| Rv2405 Rv2405 |
- |
hypothetical protein | Contains PemK_toxin (PF02452.24) domain(s); putative function inferred from the domain architecture. | PemK_toxin |
Family assigned |
| Rv2406c Rv2406c |
mtbc0_002562 |
hypothetical protein | CBS domain-containing protein. Pfam: CBS (PF00571.34). | CBS |
Family assigned |
| Rv2407 Rv2407 |
mtbc0_002563 |
ribonuclease Z | Rv2407 family type 3 sulfatase. Pfam: Anti-Pycsar_Apyc1 (PF23023.2), Lactamase_B (PF00753.34), Lactamase_B_2 (PF12706.14). | Anti-Pycsar_Apyc1 Lactamase_B Lactamase_B_2 |
Family assigned |
| PE24 Rv2408 |
- |
PE family protein PE24 | PE family protein PE24. Pfam: PE (PF00934.26). | PE |
Family assigned |
| Rv2409c Rv2409c |
mtbc0_002565 |
hypothetical protein | Transglutaminase family protein. Pfam: Bact_transglu_N (PF08379.16), Transglut_core (PF01841.26). | Bact_transglu_N Transglut_core |
Family assigned |
| Rv2410c Rv2410c |
mtbc0_002566 |
hypothetical protein | Alpha-E domain-containing protein. Pfam: Alpha-E (PF04168.18). | Alpha-E |
Family assigned |
| Rv2411c Rv2411c |
mtbc0_002567 |
hypothetical protein | Circularly permuted type 2 ATP-grasp protein. Pfam: CP_ATPgrasp_1 (PF04174.19), CP_ATPgrasp_2 (PF14403.12). | CP_ATPgrasp_1 CP_ATPgrasp_2 |
Resolved |