MTS1338 MTB000077

ncRNA Putative small regulatory RNA

This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.

Location

1960667–1960783 (+ strand), 117 nt, on H37Rv (NC_000962.3). Overlaps: Rv1734c. Upstream neighbour Rv1733c (180 bp). Downstream neighbour Rv1735c (508 bp).

Intra-MTBC variation

Genomes surveyed145,209
Variable sites109
Variants reaching 0.1 % of genomes 1
Carriers of the most widespread variant12,348

Coverage control

Variant density inside this RNA: 93.2 sites/100 bp, versus 75.3 in the flanking ±500 bp (GC 61.5 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.

Verdict: n/a (a des variants communs)

Predicted secondary structure

63.2 % of bases are paired in the minimum-free-energy fold (74 paired, 43 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).

Legacy record

MTS1338, putative small regulatory RNA (See Arnvig et al., 2011), 5'-end mapped by RLM-RACE, alternate 5'-end at position 1960601, ~100 bp band detected by Northern blot.

Sources

← all RNAs