ncRv12641 MTB000147

ncRNA Putative small regulatory RNA

This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.

Location

2966410–2966450 (+ strand), 41 nt, on H37Rv (NC_000962.3). Intergenic (no overlapping coding sequence). Upstream neighbour Rv2641 (13 bp). Downstream neighbour Rv2642 (83 bp).

Intra-MTBC variation

Genomes surveyed145,209
Variable sites30
Variants reaching 0.1 % of genomes 2
Carriers of the most widespread variant1,615

Coverage control

Variant density inside this RNA: 73.2 sites/100 bp, versus 71.1 in the flanking ±500 bp (GC 82.9 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.

Verdict: n/a (a des variants communs)

Predicted secondary structure

68.3 % of bases are paired in the minimum-free-energy fold (28 paired, 13 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).

Legacy record

Supported by sRNA-Seq in H37Rv (see DeJesus et al. 2017)

Sources

← all RNAs