MTS1082 MTB000076

ncRNA Putative small regulatory RNA

This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.

Location

1547129–1547268 (+ strand), 140 nt, on H37Rv (NC_000962.3). Overlaps: Rv1374c. Upstream neighbour Rv1373 (137 bp). Downstream neighbour Rv1375 (564 bp).

Intra-MTBC variation

Genomes surveyed145,209
Variable sites116
Variants reaching 0.1 % of genomes 1
Carriers of the most widespread variant163

Coverage control

Variant density inside this RNA: 82.9 sites/100 bp, versus 72.8 in the flanking ±500 bp (GC 62.1 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.

Verdict: n/a (a des variants communs)

Predicted secondary structure

67.1 % of bases are paired in the minimum-free-energy fold (94 paired, 46 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).

Legacy record

MTS1082, putative small regulatory RNA (See Arnvig et al., 2011), ends not mapped, ~150 bp band detected by Northern blot.

Sources

← all RNAs