ncRv10699 MTB000117

ncRNA Putative small regulatory RNA

This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.

Location

800242–800359 (+ strand), 118 nt, on H37Rv (NC_000962.3). Intergenic (no overlapping coding sequence). Upstream neighbour Rv0699 (392 bp). Downstream neighbour Rv0700 (128 bp).

Intra-MTBC variation

Genomes surveyed145,209
Variable sites102
Variants reaching 0.1 % of genomes 3
Carriers of the most widespread variant25,713

Coverage control

Variant density inside this RNA: 86.4 sites/100 bp, versus 66.3 in the flanking ±500 bp (GC 69.5 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.

Verdict: n/a (a des variants communs)

Predicted secondary structure

76.3 % of bases are paired in the minimum-free-energy fold (90 paired, 28 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).

Literature no publication

No mention of 'ncRv10699' anywhere in the TB literature corpus.

Read with care. Absence of literature does not imply absence of function; simply that no primary study addresses this locus under this name.

Sweep: tbmonitor TB corpus (~330k PubMed abstracts), single grouped UNION-ALL sweep of 2026-08-17 over the 72 ncRNA never previously searched; positive controls MTS2823 (6 papers), mcr11 (3), mcr7 (2) all returned their known hits, so a zero here is a measured absence and not a broken query.

Legacy record

Supported by sRNA-Seq in H37Rv (see DeJesus et al. 2017)

Sources

← all RNAs