MTS2823 MTB000078
ncRNA Putative small regulatory RNA
This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.
Location
4100669–4100968 (+ strand), 300 nt, on H37Rv
(NC_000962.3).
Intergenic (no overlapping coding sequence).
Upstream neighbour Rv3661
(159 bp).
Downstream neighbour Rv3662c
(297 bp).
Intra-MTBC variation
| Genomes surveyed | 145,209 |
| Variable sites | 325 |
| Variants reaching 0.1 % of genomes | 4 |
| Carriers of the most widespread variant | 676 |
Coverage control
Variant density inside this RNA: 108.3 sites/100 bp, versus 71.4 in the flanking ±500 bp (GC 61.7 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.
Verdict: n/a (a des variants communs)
Predicted secondary structure
62.7 % of bases are paired in the minimum-free-energy fold (188 paired, 112 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).
Legacy record
MTS2823, putative small regulatory RNA (See Arnvig et al., 2011), 5'-end mapped by RLM-RACE, 3'-end not mapped, ~300 bp and ~250 bp bands detected by Northern blot.
Sources
- Descriptive record (locus, name, product, comment, coordinates): Mycobrowser v5, stable RNAs (Kapopoulou et al. 2011, doi:10.1016/j.tube.2010.09.006).
- Intra-MTBC variation and coverage control: computed for this atlas over 145,209 genomes.
- Secondary structure: ViennaRNA 2.7.2, MFE fold.