MTS0858 MTB000074

ncRNA Putative small regulatory RNA

This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.

Location

1220388–1220487 (- strand), 100 nt, on H37Rv (NC_000962.3). Intergenic (no overlapping coding sequence). Upstream neighbour Rv1092c (202 bp). Downstream neighbour Rv1093 (87 bp).

Intra-MTBC variation

Genomes surveyed145,209
Variable sites69
Variants reaching 0.1 % of genomes 2
Carriers of the most widespread variant961

Coverage control

Variant density inside this RNA: 69.0 sites/100 bp, versus 57.6 in the flanking ±500 bp (GC 65.0 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.

Verdict: n/a (a des variants communs)

Predicted secondary structure

64.0 % of bases are paired in the minimum-free-energy fold (64 paired, 36 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).

Legacy record

MTS0858, putative small regulatory RNA (See Arnvig et al., 2011), ends not mapped, ~100 bp band detected by Northern blot.

Sources

← all RNAs