ASdes MTB000053
ncRNA Putative small regulatory RNA
This is an RNA, not a coding gene: it belongs to a separate track and carries none of the protein evidence layers.
Location
918264–918458 (+ strand), 195 nt, on H37Rv
(NC_000962.3).
Overlaps: Rv0824c.
Upstream neighbour Rv0823c
(618 bp).
Downstream neighbour Rv0825c
(454 bp).
Intra-MTBC variation
| Genomes surveyed | 145,209 |
| Variable sites | 61 |
| Variants reaching 0.1 % of genomes | 3 |
| Carriers of the most widespread variant | 3,577 |
Coverage control
Variant density inside this RNA: 31.3 sites/100 bp, versus 44.9 in the flanking ±500 bp (GC 62.6 %). The flanks act as an internal witness: if variants are called normally around the RNA but none becomes widespread inside it, the constraint is real rather than a sequencing gap.
Verdict: n/a (a des variants communs)
Predicted secondary structure
65.6 % of bases are paired in the minimum-free-energy fold (128 paired, 67 unpaired). Folded in isolation; the in vivo structure may differ (partners, co-transcriptional folding).
Legacy record
ASdes, putative small regulatory RNA (See Arnvig and Young, 2009). Alternate 5'-ends at positions 918350 and 918365. Alternate 3'-ends at positions 918432 and 918412.
Sources
- Descriptive record (locus, name, product, comment, coordinates): Mycobrowser v5, stable RNAs (Kapopoulou et al. 2011, doi:10.1016/j.tube.2010.09.006).
- Intra-MTBC variation and coverage control: computed for this atlas over 145,209 genomes.
- Secondary structure: ViennaRNA 2.7.2, MFE fold.