MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3903c · 46 genes shown · anchor esxE · open gene page → · ← back to 1 hop

Evidence: Min score 0
cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c Rv1359 (family_assigned) — transcriptional regulator Rv1359 PPE34 (family_assigned) — PPE family protein PPE34 PPE34 iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR PPE54 (family_assigned) — PPE family protein PPE54 PPE54 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 Rv3906c (requalified) — pullulanase Rv3906c pcnA (requalified) — poly(A) polymerase PcnA pcnA esxG (requalified) — type VII secretion system protein EsxG esxG eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr embR (requalified) — response regulator transcription factor EmbR embR kdpE (requalified) — two-component system response regulator KdpE kdpE Rv1931c (family_assigned) — transcriptional regulator Rv1931c sigI (requalified) — RNA polymerase sigma factor SigI sigI Rv1358 (family_assigned) — LuxR C-terminal-related transcriptional regulator Rv1358 Rv0894 (family_assigned) — hypothetical protein Rv0894 Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv3840 (family_assigned) — transcriptional regulator Rv3840 PPE35 (family_assigned) — PPE family protein PPE35 PPE35 espE (requalified) — type VII secretion system ESX-1 associated protein espE Rv2209 (requalified) — MFS transporter Rv2209 PE_PGRS48 (family_assigned) — PE-PGRS family protein PE_PGRS48 PE_PGRS48 mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c moaR1 (family_assigned) — transcriptional regulator MoaR1 moaR1 Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 iniB (requalified) — isoniazid-induced protein IniB iniB PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 PE_PGRS2 (family_assigned) — PE-PGRS family protein PE_PGRS2 PE_PGRS2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.