MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3862c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
whiB6 (family_assigned) — transcriptional regulator WhiB6 whiB6 Rv3863 (family_assigned) — hypothetical protein Rv3863 esxA (requalified) — ESAT-6 protein EsxA esxA whiB3 (family_assigned) — redox-responsive transcriptional regulator WhiB3 whiB3 Rv0726c (requalified) — class I SAM-dependent methyltransferase Rv0726c phoP (requalified) — two-component system response regulator PhoP phoP whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 espR (family_assigned) — type VII secretion system ESX-1 transcriptional re espR espA (requalified) — type VII secretion system ESX-1 target EspA espA espE (requalified) — type VII secretion system ESX-1 associated protein espE espG1 (requalified) — type VII secretion system ESX-1 adaptor EspG1 espG1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 espF (requalified) — type VII secretion system ESX-1 associated protein espF eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 esxO (requalified) — type VII secretion system effector EsxO esxO esxW (requalified) — type VII secretion system protein EsxW esxW Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c sigA (requalified) — RNA polymerase sigma factor sigA Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 Rv2119 (family_assigned) — RecB family exonuclease Rv2119 Rv3415c (family_assigned) — hypothetical protein Rv3415c Rv3220c (family_assigned) — histidine kinase N-terminal domain-containing prot Rv3220c Rv0725c (family_assigned) — hypothetical protein Rv0725c serA2 (requalified) — D-3-phosphoglycerate dehydrogenase SerA serA2 fucA (requalified) — L-fuculose-phosphate aldolase fucA pptT (requalified) — 4'-phosphopantetheinyl transferase pptT rnj (requalified) — ribonuclease J rnj phoR (requalified) — sensory box histidine kinase PhoR phoR Rv0600c (requalified) — two component sensor kinase HK1 Rv0600c prrB (requalified) — two-component system sensor histidine kinase PrrB prrB trcS (family_assigned) — HAMP domain-containing sensor histidine kinase trcS tcrY (requalified) — two component sensor kinase TcrY tcrY senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3 sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB secG (family_assigned) — preprotein translocase subunit SecG secG rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv0882 (dark) — DUF2537 domain-containing protein Rv0882 Rv3647c (family_assigned) — hypothetical protein Rv3647c Rv1109c (requalified) — lipid droplet-associated protein Rv1109c Rv2091c (family_assigned) — DUF4333 domain-containing protein Rv2091c rseA (requalified) — anti-sigma E factor RseA rseA espC (requalified) — type VII secretion system ESX-1 filament-forming t espC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.