MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3856c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3856c (family_assigned) — PHP domain-containing protein Rv3856c Rv3857c (family_assigned) — membrane protein Rv3857c Rv2367c (requalified) — endoribonuclease Rv2367c gltB (family_assigned) — glutamate synthase large subunit gltB ligC (requalified) — ATP-dependent DNA ligase ligC hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3 hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH purU (requalified) — formyltetrahydrofolate deformylase purU hisD (requalified) — histidinol dehydrogenase hisD hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF ligD (requalified) — ATP-dependent DNA ligase ligD Rv0104 (family_assigned) — cyclic nucleotide-binding domain-containing protei Rv0104 Rv1231c (family_assigned) — DUF1003 domain-containing protein Rv1231c Rv0145 (requalified) — class I SAM-dependent methyltransferase Rv0145 ctpB (requalified) — cation-translocating P-type ATPase ctpB pimE (requalified) — mannosyltransferase pimE phoH1 (requalified) — phosphate starvation-inducible protein PhoH phoH1 Rv2366c (family_assigned) — hemolysin family protein Rv2366c Rv2365c (requalified) — cytidine deaminase Rv2365c era (requalified) — GTPase Era era sodA (requalified) — superoxide dismutase sodA rplQ (requalified) — 50S ribosomal protein L17 rplQ gltD (family_assigned) — glutamate synthase subunit beta gltD fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB glnA1 (requalified) — type I glutamate--ammonia ligase glnA1 ligD (requalified) — non-homologous end-joining DNA ligase ligD Rv0269c (requalified) — DNA polymerase domain-containing protein Rv0269c lppK (family_assigned) — hypothetical protein lppK dnaN (family_assigned) — DNA polymerase III subunit beta dnaN Rv2090 (requalified) — 5'-3' exonuclease Rv2090 mku (requalified) — Ku protein mku hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 regX3 (requalified) — two component sensory transduction protein RegX regX3 mtrA (requalified) — two-component system response regulator MtrA mtrA prrA (requalified) — two-component system response regulator PrrA prrA mprA (requalified) — two-component system response regulator MprA mprA trcR (requalified) — two-component system response regulator TrcR trcR phoP (requalified) — two-component system response regulator PhoP phoP folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.