MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3705c · 46 genes shown · anchor gshA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3705c (family_assigned) — sensor domain-containing protein Rv3705c gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA egtC (requalified) — ergothioneine biosynthesis protein EgtC egtC egtD (requalified) — L-histidine N(alpha)-methyltransferase egtD egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE etgB (requalified) — ergothioneine biosynthesis protein EgtB etgB Rv3705A (family_assigned) — hypothetical protein Rv3705A Rv3706c (family_assigned) — hypothetical protein Rv3706c Rv2253 (family_assigned) — hypothetical protein Rv2253 lpqQ (family_assigned) — sensor domain-containing protein lpqQ Rv1352 (family_assigned) — hypothetical protein Rv1352 Rv1810 (family_assigned) — hypothetical protein Rv1810 Rv0063 (requalified) — FAD-binding oxidoreductase Rv0063 Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 ggtB (family_assigned) — gamma-glutamyltransferase family protein ggtB ggtA (requalified) — bifunctional cephalosporin acylase/gamma-glutamylt ggtA Rv3707c (requalified) — hypothetical protein Rv3707c hisD (requalified) — histidinol dehydrogenase hisD Rv1861 (family_assigned) — GlsB/YeaQ/YmgE family stress response membrane pro Rv1861 Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 spmT (requalified) — sphingomyelinase spmT asd (requalified) — aspartate-semialdehyde dehydrogenase asd ask (requalified) — aspartate kinase ask Rv2252 (requalified) — diacylglycerol kinase Rv2252 glpD1 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD1 Rv2251 (requalified) — flavoprotein Rv2251 Rv2250A (family_assigned) — Possible flavoprotein Rv2250A Rv2250c (family_assigned) — TetR/AcrR family transcriptional regulator Rv2250c Rv3198A (requalified) — glutaredoxin protein Rv3198A lppH (requalified) — lipoprotein LppH lppH Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 lpqA (family_assigned) — sensor domain-containing protein lpqA Rv0963c (family_assigned) — hypothetical protein Rv0963c Rv1351 (dark) — hypothetical protein Rv1351 fabG2 (requalified) — 3-oxoacyl-ACP reductase FabG fabG2 lppO (requalified) — lipoprotein LpqH lppO PPE26 (family_assigned) — PPE family protein PPE26 PPE26 Rv0431 (requalified) — tuberculin-like peptide Rv0431 mgtC (family_assigned) — MgtC/SapB family protein mgtC PPE33 (family_assigned) — PPE family protein PPE33 PPE33 PPE32 (family_assigned) — PPE family protein PPE32 PPE32 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 Rv3717 (family_assigned) — hypothetical protein Rv3717 xerC (requalified) — tyrosine recombinase XerC xerC hsr1 (requalified) — hypothetical protein hsr1 sigD (requalified) — ECF RNA polymerase sigma factor SigD sigD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.