Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3701c · 46 genes shown · anchor etgB · open gene page → · ← back to 1 hop

Evidence: Min score 0
egtD (requalified) — L-histidine N(alpha)-methyltransferase egtD etgB (requalified) — ergothioneine biosynthesis protein EgtB etgB egtC (requalified) — ergothioneine biosynthesis protein EgtC egtC gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE hisD (requalified) — histidinol dehydrogenase hisD Rv1861 (family_assigned) — GlsB/YeaQ/YmgE family stress response membrane pro Rv1861 Rv3705c (family_assigned) — sensor domain-containing protein Rv3705c Rv1670 (family_assigned) — DUF427 domain-containing protein Rv1670 Rv0140 (family_assigned) — DUF427 domain-containing protein Rv0140 Rv0925c (family_assigned) — flavodoxin family protein Rv0925c Rv0712 (family_assigned) — formylglycine-generating enzyme family protein Rv0712 Rv3680 (family_assigned) — ArsA family ATPase Rv3680 Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 Rv3707c (requalified) — hypothetical protein Rv3707c ggtB (family_assigned) — gamma-glutamyltransferase family protein ggtB ggtA (requalified) — bifunctional cephalosporin acylase/gamma-glutamylt ggtA Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 spmT (requalified) — sphingomyelinase spmT hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI adhA (family_assigned) — zinc-binding alcohol dehydrogenase family protein adhA Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c apa (family_assigned) — hypothetical protein apa modC (family_assigned) — sulfate/molybdate ABC transporter ATP-binding prot modC Rv1954A (dark) — Hypothetical protein Rv1954A Rv3705A (family_assigned) — hypothetical protein Rv3705A Rv1671 (dark) — hypothetical protein Rv1671 Rv1669 (dark) — hypothetical protein Rv1669 Rv1056 (family_assigned) — DUF427 domain-containing protein Rv1056 Rv0139 (family_assigned) — NAD-dependent epimerase/dehydratase family protein Rv0139 Rv0138 (family_assigned) — nuclear transport factor 2 family protein Rv0138 msrA (requalified) — peptide-methionine (S)-S-oxide reductase MsrA msrA Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c Rv0569 (family_assigned) — DUF1918 domain-containing protein Rv0569 mntH (requalified) — divalent metal cation transporter MntH mntH Rv0923c (family_assigned) — poly-gamma-glutamate hydrolase family protein Rv0923c Rv0007 (dark) — DUF3566 domain-containing protein Rv0007 Rv0926c (requalified) — diacylglycerol kinase Rv0926c Rv0927c (family_assigned) — SDR family oxidoreductase Rv0927c rpfC (requalified) — resuscitation-promoting factor RpfC rpfC Rv3077 (requalified) — hydrolase Rv3077

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.