MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3699 · 46 genes shown · anchor eccD3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3699 (requalified) — class I SAM-dependent methyltransferase Rv3699 Rv3698 (family_assigned) — hypothetical protein Rv3698 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 vapC48 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC48 vapB48 (requalified) — antitoxin VapB48 vapB48 Rv2751 (requalified) — class I SAM-dependent methyltransferase Rv2751 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG glpK (requalified) — glycerol kinase GlpK glpK PPE2 (family_assigned) — PPE family protein PPE2 PPE2 Rv2687c (family_assigned) — fluoroquinolone transporter permease Rv2687c eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 Rv3896c (requalified) — transglycosylase Rv3896c Rv2686c (family_assigned) — fluoroquinolones efflux ABC transporter permease Rv2686c Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c Rv0857 (family_assigned) — hypothetical protein Rv0857 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 vapB43 (family_assigned) — ribbon-helix-helix domain-containing protein vapB43 vapC25 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC25 vapC31 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC31 Rv3749c (family_assigned) — hypothetical protein Rv3749c Rv0298 (family_assigned) — ribbon-helix-helix protein%2C CopG family Rv0298 Rv2750 (family_assigned) — Rv2750 family mycofactocin-dependent SDR oxidoredu Rv2750 Rv2749 (family_assigned) — putative quinol monooxygenase Rv2749 Rv1896c (requalified) — class I SAM-dependent methyltransferase Rv1896c Rv3767c (requalified) — class I SAM-dependent methyltransferase Rv3767c Rv0893c (requalified) — class I SAM-dependent methyltransferase Rv0893c Rv0281 (requalified) — class I SAM-dependent methyltransferase Rv0281 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtC (requalified) — polyketide synthetase MbtC mbtC glpD2 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD2 mpa (requalified) — proteasome ATPase mpa mec (requalified) — CysO-cysteine peptidase mec glpD1 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD1 prcB (family_assigned) — proteasome subunit beta prcB prcA (family_assigned) — proteasome subunit alpha prcA cobQ1 (requalified) — cobyric acid synthase cobQ1 pirG (requalified) — exported repetitive protein pirG Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.