MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3681c · 46 genes shown · anchor secG · open gene page → · ← back to 1 hop

Evidence: Min score 0
whiB4 (family_assigned) — transcriptional regulator WhiB4 whiB4 apt (requalified) — adenine phosphoribosyltransferase apt secG (family_assigned) — preprotein translocase subunit SecG secG Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ Rv0525 (family_assigned) — histidine phosphatase family protein Rv0525 rshA (requalified) — anti-sigma factor RshA rshA Rv1321 (requalified) — endonuclease NucS Rv1321 clpS (requalified) — ATP-dependent Clp protease adapter ClpS clpS Rv2478c (family_assigned) — hypothetical protein Rv2478c Rv3683 (requalified) — metallophosphoesterase Rv3683 rslA (requalified) — anti-sigma-L factor RslA rslA guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purB (requalified) — adenylosuccinate lyase purB purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH gmk (requalified) — guanylate kinase gmk deoD (requalified) — purine-nucleoside phosphorylase deoD adoK (family_assigned) — carbohydrate kinase family protein adoK secE1 (requalified) — preprotein translocase SecE secE1 secY (family_assigned) — preprotein translocase subunit SecY secY yidC (requalified) — membrane protein insertase YidC yidC secA1 (family_assigned) — protein translocase subunit SecA secA1 secA2 (requalified) — accessory Sec system translocase SecA2 secA2 ftsY (requalified) — signal recognition particle-docking protein FtsY ftsY rnhB (requalified) — ribonuclease HII rnhB lepB (requalified) — signal peptidase I lepB whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 whiB2 (family_assigned) — transcriptional regulator WhiB2 whiB2 rplS (requalified) — 50S ribosomal protein L19 rplS rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA Rv2699c (dark) — DUF4193 domain-containing protein Rv2699c rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB sigA (requalified) — RNA polymerase sigma factor sigA helZ (requalified) — DEAD/DEAH box helicase helZ Rv0526 (requalified) — thioredoxin Rv0526 hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL ccdA (requalified) — cytochrome C-type biogenesis protein CcdA ccdA Rv0528 (requalified) — cytochrome c biogenesis protein ResB Rv0528 ccsA (requalified) — c-type cytochrome biogenesis protein CcsB ccsA sigH (family_assigned) — sigma-70 family RNA polymerase sigma factor SigH sigH Rv3222c (family_assigned) — hypothetical protein Rv3222c TB7.3 (requalified) — biotin/lipoyl-binding carrier protein TB7.3 Rv3224 (requalified) — NAD(P)-dependent oxidoreductase Rv3224

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.