MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3646c · 46 genes shown · anchor cspA · open gene page → · ← back to 1 hop

Evidence: Min score 0
topA (requalified) — type I DNA topoisomerase topA Rv2529 (family_assigned) — hypothetical protein Rv2529 Rv1278 (family_assigned) — AAA family ATPase Rv1278 recA (requalified) — intein-containing recombinase RecA recA polA (requalified) — DNA polymerase I polA Rv1277 (family_assigned) — hypothetical protein Rv1277 Rv2090 (requalified) — 5'-3' exonuclease Rv2090 dinG (requalified) — ATP-dependent helicase DinG dinG Rv3647c (family_assigned) — hypothetical protein Rv3647c cspA (requalified) — cold shock protein CspA cspA dnaN (family_assigned) — DNA polymerase III subunit beta dnaN gltB (family_assigned) — glutamate synthase large subunit gltB Rv2478c (family_assigned) — hypothetical protein Rv2478c lprE (family_assigned) — LppP/LprE family lipoprotein lprE rplA (requalified) — 50S ribosomal protein L1 rplA Rv1279 (family_assigned) — GMC family oxidoreductase N-terminal domain-contai Rv1279 recX (requalified) — recombination regulator RecX recX lexA (requalified) — transcriptional repressor LexA lexA radA (requalified) — DNA repair protein RadA radA lppK (family_assigned) — hypothetical protein lppK ligC (requalified) — ATP-dependent DNA ligase ligC rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB mec (requalified) — CysO-cysteine peptidase mec espR (family_assigned) — type VII secretion system ESX-1 transcriptional re espR Rv0996 (family_assigned) — hypothetical protein Rv0996 ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 rpsL (requalified) — 30S ribosomal protein S12 rpsL rplO (requalified) — 50S ribosomal protein L15 rplO tuf (requalified) — elongation factor Tu tuf rpmJ (requalified) — 50S ribosomal protein L36 rpmJ esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ rpmE (requalified) — 50S ribosomal protein L31 rpmE dnaE1 (family_assigned) — DNA polymerase III subunit alpha dnaE1 Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c Rv3644c (family_assigned) — DNA polymerase III subunit delta' Rv3644c dnaZX (family_assigned) — DNA polymerase III subunits gamma/tau dnaZX dnaA (requalified) — chromosomal replication initiator protein DnaA dnaA gltD (family_assigned) — glutamate synthase subunit beta gltD fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB glnA1 (requalified) — type I glutamate--ammonia ligase glnA1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.