MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3616c · 46 genes shown · anchor espC · open gene page → · ← back to 1 hop

Evidence: Min score 0
espA (requalified) — type VII secretion system ESX-1 target EspA espA espC (requalified) — type VII secretion system ESX-1 filament-forming t espC espD (requalified) — type VII secretion system ESX-1 target EspD espD Rv3613c (family_assigned) — hypothetical protein Rv3613c Rv3612c (dark) — hypothetical protein Rv3612c esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 Rv1084 (family_assigned) — thioredoxin domain-containing protein Rv1084 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 ftsK (requalified) — DNA translocase FtsK ftsK espE (requalified) — type VII secretion system ESX-1 associated protein espE espH (requalified) — type VII secretion system ESX-1 associated protein espH espL (requalified) — type VII secretion system ESX-1 associated protein espL lipQ (family_assigned) — alpha/beta hydrolase lipQ trxA (family_assigned) — thioredoxin family protein trxA esxA (requalified) — ESAT-6 protein EsxA esxA esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ esxL (requalified) — type VII secretion system ESX-5 protein EsxL esxL esxW (requalified) — type VII secretion system protein EsxW esxW omamA (requalified) — hypothetical protein omamA omamB (requalified) — hypothetical protein omamB polA (requalified) — DNA polymerase I polA ruvB (requalified) — Holliday junction branch migration DNA helicase Ru ruvB Rv3633 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv3633 Rv1501 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv1501 mca (requalified) — mycothiol conjugate amidase Mca mca Rv1083 (dark) — hypothetical protein Rv1083 Rv1081c (dark) — DUF4307 domain-containing protein Rv1081c Rv0519c (family_assigned) — membrane protein Rv0519c Rv1987 (family_assigned) — cellulose-binding protein Rv1987 celA1 (requalified) — cellulase CelA celA1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 espF (requalified) — type VII secretion system ESX-1 associated protein espF eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.