MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3613c · 46 genes shown · anchor espD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3613c (family_assigned) — hypothetical protein Rv3613c espD (requalified) — type VII secretion system ESX-1 target EspD espD Rv3612c (dark) — hypothetical protein Rv3612c espC (requalified) — type VII secretion system ESX-1 filament-forming t espC espA (requalified) — type VII secretion system ESX-1 target EspA espA lipQ (family_assigned) — alpha/beta hydrolase lipQ trxA (family_assigned) — thioredoxin family protein trxA lprQ (requalified) — L%2CD-transpeptidase LdtMt5 lprQ Rv0188 (requalified) — SPW repeat protein Rv0188 Rv3839 (requalified) — DUF2470 domain-containing protein Rv3839 espL (requalified) — type VII secretion system ESX-1 associated protein espL eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 esxA (requalified) — ESAT-6 protein EsxA esxA espE (requalified) — type VII secretion system ESX-1 associated protein espE espH (requalified) — type VII secretion system ESX-1 associated protein espH esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 fadD11.1 (family_assigned) — Possible fatty-acid-CoA ligase FadD11.1 (fatty-aci fadD11.1 fadD11 (requalified) — fatty-acid--CoA ligase FadD11 fadD11 Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 fadD5 (requalified) — fatty-acid--CoA ligase FadD5 fadD5 Rv0310c (family_assigned) — nuclear transport factor 2 family protein Rv0310c Rv2484c (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv2484c trxB1 (requalified) — thioredoxin trxB1 trxB2 (requalified) — thioredoxin-disulfide reductase trxB2 echA12 (requalified) — enoyl-CoA hydratase echA12 ctpD (requalified) — cobalt-translocating P-type ATPase CtpD ctpD Rv1473 (family_assigned) — macrolide ABC transporter ATP-binding protein Rv1473 htpG (requalified) — molecular chaperone HtpG htpG Rv0481c (family_assigned) — DUF2505 domain-containing protein Rv0481c murB (requalified) — UDP-N-acetylmuramate dehydrogenase murB Rv0480c (family_assigned) — carbon-nitrogen hydrolase family protein Rv0480c Rv1332 (family_assigned) — transcriptional regulator Rv1332 Rv3015c (requalified) — methionine synthase Rv3015c Rv0990c (family_assigned) — SAF domain-containing protein Rv0990c Rv0048c (family_assigned) — DUF1707 domain-containing protein Rv0048c Rv1171 (family_assigned) — hypothetical protein Rv1171 Rv1635c (family_assigned) — glycosyltransferase family 39 protein Rv1635c Rv0187 (requalified) — O-methyltransferase Rv0187 Rv1885c (requalified) — chorismate mutase Rv1885c Rv3773c (family_assigned) — TIGR03086 family metal-binding protein Rv3773c mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA PPE37 (family_assigned) — PPE family protein PPE37 PPE37 pheA (requalified) — prephenate dehydratase pheA Rv3837c (family_assigned) — histidine phosphatase family protein Rv3837c Rv0010c (family_assigned) — PH domain-containing protein Rv0010c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.