MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3605c · 46 genes shown · anchor folE · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3605c (family_assigned) — DUF3180 domain-containing protein Rv3605c folE (requalified) — GTP cyclohydrolase I FolE folE folK (requalified) — 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine folK folP1 (requalified) — dihydropteroate synthase folP1 folB (requalified) — dihydroneopterin aldolase folB ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c 35kd_ag (family_assigned) — hypothetical protein 35kd_ag Rv2179c (requalified) — polyadenylate-specific 3'-exoribonuclease AS Rv2179c Rv2468c (requalified) — hypothetical protein Rv2468c Rv0948c (requalified) — chorismate mutase Rv0948c Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 Rv2170 (requalified) — N-acetyltransferase Rv2170 ribA2 (requalified) — bifunctional 3%2C4-dihydroxy-2-butanone-4-phosphat ribA2 ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 folP2 (requalified) — dihydropteroate synthase folP2 folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 Rv3090 (family_assigned) — SPFH domain-containing protein Rv3090 rplS (requalified) — 50S ribosomal protein L19 rplS Rv0955 (family_assigned) — DUF6350 family protein Rv0955 rsmA (requalified) — anti-sigma-M factor RsmA rsmA pimE (requalified) — mannosyltransferase pimE Rv0804 (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0804 PPE2 (family_assigned) — PPE family protein PPE2 PPE2 clgR (family_assigned) — transcriptional regulator ClgR clgR Rv2743c (family_assigned) — hypothetical protein Rv2743c htpX (requalified) — zinc metalloprotease HtpX htpX sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB Rv2180c (family_assigned) — integral membrane protein Rv2180c aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG Rv2181 (requalified) — alpha-(1-2)-phosphatidylinositol mannoside mannosy Rv2181 Rv2468A (family_assigned) — hypothetical protein Rv2468A qcrA (requalified) — hypothetical protein qcrA Rv2199c (family_assigned) — cytochrome c oxidase subunit 4 Rv2199c ctaC (family_assigned) — cytochrome c oxidase subunit II ctaC qcrB (family_assigned) — cytochrome bc complex cytochrome b subunit qcrB Rv1638A (family_assigned) — hypothetical protein Rv1638A aroF (requalified) — chorismate synthase aroF tyrA (requalified) — prephenate dehydrogenase TyrA tyrA pheA (requalified) — prephenate dehydratase pheA trpE (requalified) — anthranilate synthase component I trpE Rv1885c (requalified) — chorismate mutase Rv1885c guaB2 (requalified) — IMP dehydrogenase guaB2 guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 Rv3231c (family_assigned) — hypothetical protein Rv3231c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.