Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3593 · 46 genes shown · anchor mhuD · open gene page → · ← back to 1 hop

Evidence: Min score 0
lpqF (requalified) — serine hydrolase lpqF mhuD (requalified) — mycobilin-forming heme oxygenase MhuD mhuD Rv3591c (family_assigned) — alpha/beta hydrolase Rv3591c pirG (requalified) — exported repetitive protein pirG Rv3707c (requalified) — hypothetical protein Rv3707c Rv2743c (family_assigned) — hypothetical protein Rv2743c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 lmeA (requalified) — mannan chain length control protein LmeA lmeA Rv0479c (family_assigned) — DUF2993 domain-containing protein Rv0479c thiS (requalified) — sulfur carrier protein ThiS thiS Rv0518 (family_assigned) — SGNH/GDSL hydrolase family protein Rv0518 lprC (family_assigned) — DUF3558 domain-containing protein lprC Rv0320 (family_assigned) — hypothetical protein Rv0320 hycE (family_assigned) — NADH-quinone oxidoreductase subunit C hycE Rv3594 (requalified) — N-acetylmuramoyl-L-alanine amidase Rv3594 Rv0959 (family_assigned) — VWA domain-containing protein Rv0959 PE_PGRS58 (family_assigned) — PE-PGRS family protein PE_PGRS58 PE_PGRS58 lipV (requalified) — lipase LipV lipV octT (requalified) — diglucosylglycerate octanoyltransferase octT Rv3415c (family_assigned) — hypothetical protein Rv3415c Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC ripA (family_assigned) — NlpC/P60 family peptidoglycan endopeptidase RipA ripA Rv1158c (dark) — hypothetical protein Rv1158c mtc28 (family_assigned) — LpqN/LpqT family lipoprotein mtc28 ask (requalified) — aspartate kinase ask asd (requalified) — aspartate-semialdehyde dehydrogenase asd 35kd_ag (family_assigned) — hypothetical protein 35kd_ag lppL (family_assigned) — hypothetical protein lppL chiZ (requalified) — cell wall hydrolase ChiZ chiZ eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 thiX (family_assigned) — thioredoxin family protein thiX ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA hbhA (requalified) — heparin-binding hemagglutinin HbhA hbhA Rv0480c (family_assigned) — carbon-nitrogen hydrolase family protein Rv0480c Rv0481c (family_assigned) — DUF2505 domain-containing protein Rv0481c Rv0227c (family_assigned) — membrane protein Rv0227c Rv1476 (family_assigned) — DUF6676 family protein Rv1476 PPE2 (family_assigned) — PPE family protein PPE2 PPE2 thiG (requalified) — thiazole synthase thiG

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.