MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3581c · 38 genes shown · anchor ispD · open gene page → · ← back to 1 hop

Evidence: Min score 0
ispF (requalified) — 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate syn ispF ispD (requalified) — 2-C-methyl-D-erythritol 4-phosphate cytidylyltrans ispD gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE ispE (requalified) — 4-diphosphocytidyl-2C-methyl-D-erythritol kinase ispE carD (requalified) — RNA polymerase-binding transcription factor CarD carD rlmB (requalified) — 23S rRNA (guanosine(2251)-2'-O)-methyltransferase rlmB cysS1 (requalified) — cysteine--tRNA ligase cysS1 dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr Rv3382c (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Rv3382c lytB2 (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase lytB2 dxs1 (requalified) — 1-deoxy-D-xylulose 5-phosphate synthase dxs1 dxs2 (requalified) — 1-deoxy-D-xylulose-5-phosphate synthase dxs2 disA (requalified) — DNA integrity scanning diadenylate cyclase DisA disA Rv2867c (family_assigned) — GNAT family N-acetyltransferase Rv2867c rip (requalified) — zinc metalloprotease Rip rip ksgA (requalified) — 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-d ksgA rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ sigA (requalified) — RNA polymerase sigma factor sigA whiB7 (family_assigned) — transcriptional regulator WhiB7 whiB7 rplK (requalified) — 50S ribosomal protein L11 rplK pheT (family_assigned) — phenylalanine--tRNA ligase subunit beta pheT cysE (requalified) — serine O-acetyltransferase cysE serS (requalified) — serine--tRNA ligase serS idsB (family_assigned) — polyprenyl synthetase family protein idsB rpsA (requalified) — 30S ribosomal protein S1 rpsA idsA2 (requalified) — bifunctional (2E%2C6E)-farnesyl/geranyl diphosphat idsA2 idsA1 (requalified) — multifunctional dimethylallyltransferase/geranyltr idsA1 thiG (requalified) — thiazole synthase thiG Rv3378c (requalified) — diterpene synthase Rv3378c Rv3377c (requalified) — type B diterpene cyclase Rv3377c radA (requalified) — DNA repair protein RadA radA lpqE (family_assigned) — hypothetical protein lpqE adnA (requalified) — ATP-dependent DNA helicase AdnA adnA Rv3714c (family_assigned) — hypothetical protein Rv3714c Rv2375 (family_assigned) — type II toxin-antitoxin system VapB family antitox Rv2375

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.