MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3535c · 46 genes shown · anchor hsaF · open gene page → · ← back to 1 hop

Evidence: Min score 0
hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG hsaF (requalified) — 4-hydroxy-2-oxovalerate aldolase hsaF mhpE (requalified) — 4-hydroxy-2-oxovalerate aldolase mhpE hsaE (requalified) — 2-keto-4-pentenoate hydratase hsaE leuA (requalified) — 2-isopropylmalate synthase leuA fadA5 (requalified) — steroid 3-ketoacyl-CoA thiolase fadA5 aldA (requalified) — aldehyde dehydrogenase aldA Rv0223c (requalified) — aldehyde dehydrogenase Rv0223c Rv0147 (requalified) — aldehyde dehydrogenase Rv0147 Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 pcd (requalified) — piperideine-6-carboxylic acid dehydrogenase pcd ltp3 (family_assigned) — thiolase domain-containing protein ltp3 fadA (requalified) — acetyl-CoA C-acetyltransferase fadA Rv3538 (requalified) — dehydrogenase Rv3538 kstD (requalified) — 3-oxosteroid 1-dehydrogenase kstD leuB (requalified) — 3-isopropylmalate dehydrogenase leuB ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 Rv3468c (requalified) — dTDP-glucose 4,6-dehydratase Rv3468c hsaD (requalified) — alpha/beta fold hydrolase hsaD leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD ilvD (requalified) — dihydroxy-acid dehydratase ilvD ilvE (requalified) — branched-chain amino acid aminotransferase ilvE accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 fadB (requalified) — fatty oxidation protein FadB fadB fadB2 (requalified) — 3-hydroxybutyryl-CoA dehydrogenase FadB2 fadB2 fadB3 (requalified) — 3-hydroxybutyryl-CoA dehydrogenase FadB fadB3 fadE29 (requalified) — acyl-CoA dehydrogenase FadE29 fadE29 chsH2 (family_assigned) — 3-oxo-23%2C24-bisnorchol-4%2C17(20)-dien-22-oyl-Co chsH2 fadE28 (requalified) — acyl-CoA dehydrogenase FadE28 fadE28 Rv0765c (family_assigned) — SDR family oxidoreductase Rv0765c Rv0770 (requalified) — NAD(P)-dependent oxidoreductase Rv0770 adhB (requalified) — alcohol dehydrogenase B adhB cyp123 (requalified) — cytochrome P450 cyp123 acs (requalified) — acetate--CoA ligase acs cyp51 (requalified) — lanosterol 14-alpha demethylase cyp51 gabT (requalified) — 4-aminobutyrate--2-oxoglutarate transaminase gabT mmsA (requalified) — CoA-acylating methylmalonate-semialdehyde dehydrog mmsA ackA (requalified) — acetate kinase ackA Rv0459 (family_assigned) — DUF779 domain-containing protein Rv0459 adhE1 (family_assigned) — zinc-type alcohol dehydrogenase subunit E adhE1 adh (requalified) — zinc-binding dehydrogenase adh Rv3292 (family_assigned) — VOC family protein Rv3292 Rv3521 (family_assigned) — hypothetical protein Rv3521 Rv0914c (requalified) — acetyl-CoA acetyltransferase Rv0914c glcB (requalified) — malate synthase G glcB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.