MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3451 · 46 genes shown · anchor eccB4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
cut3 (family_assigned) — cutinase family protein cut3 eccB4 (family_assigned) — type VII secretion system ESX-4 subunit EccB4 eccB4 cut4 (requalified) — cutinase Cut4 cut4 Rv1278 (family_assigned) — AAA family ATPase Rv1278 Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747 ptbB (requalified) — tyrosine-protein phosphatase PtbB ptbB nuoM (family_assigned) — NADH-quinone oxidoreductase subunit M nuoM Rv0434 (family_assigned) — LON peptidase substrate-binding domain-containing Rv0434 TB22.2 (family_assigned) — RsiV family protein TB22.2 PE23 (family_assigned) — PE family protein PE23 PE23 PE_PGRS62 (family_assigned) — PE-PGRS family protein PE_PGRS62 PE_PGRS62 PE_PGRS12 (family_assigned) — PE-PGRS family protein PE_PGRS12 PE_PGRS12 fhaA (requalified) — cell division-associated protein FhaA fhaA eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 Rv3657c (family_assigned) — membrane protein Rv3657c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 Rv1592c (family_assigned) — lipase family protein Rv1592c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 spmT (requalified) — sphingomyelinase spmT Rv1277 (family_assigned) — hypothetical protein Rv1277 Rv1279 (family_assigned) — GMC family oxidoreductase N-terminal domain-contai Rv1279 polA (requalified) — DNA polymerase I polA topA (requalified) — type I DNA topoisomerase topA recA (requalified) — intein-containing recombinase RecA recA Rv2090 (requalified) — 5'-3' exonuclease Rv2090 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c pknB (family_assigned) — Stk1 family PASTA domain-containing Ser/Thr kinase pknB pknF (requalified) — serine/threonine protein kinase PknF pknF Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c fadE2 (requalified) — acyl-CoA dehydrogenase fadE2 ptpA (requalified) — protein-tyrosine-phosphatase ptpA nuoB (family_assigned) — NADH-quinone oxidoreductase subunit B nuoB nuoH (family_assigned) — NADH-quinone oxidoreductase subunit NuoH nuoH nuoA (family_assigned) — NADH-quinone oxidoreductase subunit A nuoA nuoI (family_assigned) — NADH-quinone oxidoreductase subunit NuoI nuoI nuoE (family_assigned) — NADH-quinone oxidoreductase subunit NuoE nuoE nuoJ (family_assigned) — NADH-quinone oxidoreductase subunit J nuoJ nuoG (family_assigned) — NADH-quinone oxidoreductase subunit G nuoG Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 sodC (family_assigned) — superoxide dismutase family protein sodC Rv0431 (requalified) — tuberculin-like peptide Rv0431 napA (requalified) — DUF3263 domain-containing protein napA Rv2133c (family_assigned) — SCO1664 family protein Rv2133c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.