MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3446c · 36 genes shown · anchor eccD4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 htpG (requalified) — molecular chaperone HtpG htpG mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT esxT (family_assigned) — WXG100 family type VII secretion target esxT esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU Rv3196 (family_assigned) — hypothetical protein Rv3196 clpC1 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC1 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 dnaK (requalified) — molecular chaperone DnaK dnaK Rv2264c (family_assigned) — Hsp70 family protein Rv2264c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5 hspR (family_assigned) — heat shock transcriptional regulator HspR hspR clpB (requalified) — chaperone protein ClpB clpB groEL2 (requalified) — chaperonin GroEL groEL2 Rv2372c (requalified) — 16S rRNA (uracil(1498)-N(3))-methyltransferase Rv2372c hrcA (requalified) — heat-inducible transcriptional repressor HrcA hrcA ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c rplM (requalified) — 50S ribosomal protein L13 rplM eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 moaX (requalified) — MoaD-MoaE fusion protein MoaX moaX Rv3195 (requalified) — zinc-dependent metalloprotease Rv3195 thiS (requalified) — sulfur carrier protein ThiS thiS clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 clpS (requalified) — ATP-dependent Clp protease adapter ClpS clpS clpP1 (family_assigned) — ATP-dependent CLP protease proteolytic subunit 1 clpP1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.