MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3444c · 46 genes shown · anchor esxU · open gene page → · ← back to 1 hop

Evidence: Min score 0
esxT (family_assigned) — WXG100 family type VII secretion target esxT esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 rplM (requalified) — 50S ribosomal protein L13 rplM lpqB (requalified) — MtrAB system accessory lipoprotein LpqB lpqB fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c Rv2743c (family_assigned) — hypothetical protein Rv2743c cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv0756c (family_assigned) — hypothetical protein Rv0756c eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5 Rv3196 (family_assigned) — hypothetical protein Rv3196 rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY rpmG2 (requalified) — 50S ribosomal protein L33 rpmG2 rpmE (requalified) — 50S ribosomal protein L31 rpmE rplR (requalified) — 50S ribosomal protein L18 rplR rpmA (requalified) — 50S ribosomal protein L27 rpmA rplQ (requalified) — 50S ribosomal protein L17 rplQ mtrB (requalified) — two-component system sensor histidine kinase MtrB mtrB mtrA (requalified) — two-component system response regulator MtrA mtrA Rv3243c (family_assigned) — LmeA family phospholipid-binding protein Rv3243c Rv3802c (requalified) — phospholipase Rv3802c lprC (family_assigned) — DUF3558 domain-containing protein lprC Rv3668c (requalified) — protease Rv3668c fbpA (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpA fbpB (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpB lipY (requalified) — triacylglycerol lipase Lip lipY Rv2252 (requalified) — diacylglycerol kinase Rv2252 pirG (requalified) — exported repetitive protein pirG aftB (requalified) — terminal beta-(1->2)-arabinofuranosyltransferase aftB cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr embR (requalified) — response regulator transcription factor EmbR embR kdpE (requalified) — two-component system response regulator KdpE kdpE Rv1931c (family_assigned) — transcriptional regulator Rv1931c sigI (requalified) — RNA polymerase sigma factor SigI sigI Rv1359 (family_assigned) — transcriptional regulator Rv1359 35kd_ag (family_assigned) — hypothetical protein 35kd_ag

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.