MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3412 · 46 genes shown · anchor guaB2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 guaB2 (requalified) — IMP dehydrogenase guaB2 guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 Rv2179c (requalified) — polyadenylate-specific 3'-exoribonuclease AS Rv2179c Rv3605c (family_assigned) — DUF3180 domain-containing protein Rv3605c Rv3231c (family_assigned) — hypothetical protein Rv3231c 35kd_ag (family_assigned) — hypothetical protein 35kd_ag Rv2170 (requalified) — N-acetyltransferase Rv2170 Rv2468c (requalified) — hypothetical protein Rv2468c Rv3519 (family_assigned) — acetoacetate decarboxylase family protein Rv3519 Rv0948c (requalified) — chorismate mutase Rv0948c rshA (requalified) — anti-sigma factor RshA rshA Rv3205c (family_assigned) — hypothetical protein Rv3205c guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB Rv2180c (family_assigned) — integral membrane protein Rv2180c aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG Rv2181 (requalified) — alpha-(1-2)-phosphatidylinositol mannoside mannosy Rv2181 folE (requalified) — GTP cyclohydrolase I FolE folE folK (requalified) — 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine folK folP1 (requalified) — dihydropteroate synthase folP1 folB (requalified) — dihydroneopterin aldolase folB ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c ppk2 (requalified) — polyphosphate kinase ppk2 Rv3230c (requalified) — NADPH oxidoreductase Rv3230c Rv3233c (family_assigned) — Possible triacylglycerol synthase (diacylglycerol Rv3233c tgs3 (requalified) — diacyglycerol O-acyltransferase tgs3 clgR (family_assigned) — transcriptional regulator ClgR clgR Rv2743c (family_assigned) — hypothetical protein Rv2743c htpX (requalified) — zinc metalloprotease HtpX htpX sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB Rv2169c (dark) — DUF3040 domain-containing protein Rv2169c lppM (requalified) — lipoprotein LppM lppM Rv3311 (family_assigned) — primosomal protein Rv3311 Rv2520c (dark) — DUF3618 domain-containing protein Rv2520c Rv3212 (family_assigned) — hypothetical protein Rv3212 Rv2468A (family_assigned) — hypothetical protein Rv2468A qcrA (requalified) — hypothetical protein qcrA Rv2199c (family_assigned) — cytochrome c oxidase subunit 4 Rv2199c ctaC (family_assigned) — cytochrome c oxidase subunit II ctaC qcrB (family_assigned) — cytochrome bc complex cytochrome b subunit qcrB Rv1638A (family_assigned) — hypothetical protein Rv1638A

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.