MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3411c · 46 genes shown · anchor guaA · open gene page → · ← back to 1 hop

Evidence: Min score 0
guaB2 (requalified) — IMP dehydrogenase guaB2 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB hpt (requalified) — hypoxanthine phosphoribosyltransferase hpt Rv1021 (requalified) — nucleoside triphosphate pyrophosphohydrolase Rv1021 purF (requalified) — amidophosphoribosyltransferase purF choD (requalified) — cholesterol oxidase choD Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 pheT (family_assigned) — phenylalanine--tRNA ligase subunit beta pheT apt (requalified) — adenine phosphoribosyltransferase apt argS (requalified) — arginine--tRNA ligase argS rplK (requalified) — 50S ribosomal protein L11 rplK purB (requalified) — adenylosuccinate lyase purB Rv0356c (family_assigned) — PaaI family thioesterase Rv0356c purN (requalified) — phosphoribosylglycinamide formyltransferase purN glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT rphA (requalified) — ribonuclease PH rphA murI (requalified) — glutamate racemase murI ndkA (requalified) — nucleoside-diphosphate kinase ndkA mesJ (requalified) — tRNA lysidine(34) synthetase TilS mesJ deoD (requalified) — purine-nucleoside phosphorylase deoD purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM purD (requalified) — phosphoribosylamine--glycine ligase purD purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB Rv1106c (requalified) — 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-is Rv1106c cyp142 (requalified) — steroid C26-monooxygenase Cyp142 cyp142 cyp125 (requalified) — steroid C26-monooxygenase cyp125 qcrC (requalified) — cytochrome c qcrC Rv2267c (requalified) — sulfotransferase Rv2267c Rv2179c (requalified) — polyadenylate-specific 3'-exoribonuclease AS Rv2179c Rv3605c (family_assigned) — DUF3180 domain-containing protein Rv3605c Rv3231c (family_assigned) — hypothetical protein Rv3231c 35kd_ag (family_assigned) — hypothetical protein 35kd_ag pheS (family_assigned) — phenylalanine--tRNA ligase subunit alpha pheS leuS (requalified) — leucine--tRNA ligase leuS ileS (requalified) — isoleucine--tRNA ligase ileS rpsB (requalified) — 30S ribosomal protein S2 rpsB rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.