MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3405c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3405c (family_assigned) — helix-turn-helix domain-containing protein Rv3405c cobB (requalified) — NAD-dependent protein deacylase cobB Rv3406 (requalified) — alpha-ketoglutarate-dependent sulfate ester dioxyg Rv3406 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv2282c (family_assigned) — LysR family transcriptional regulator Rv2282c Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 parD1 (family_assigned) — type II toxin-antitoxin system ParD family antitox parD1 Rv0494 (family_assigned) — HTH-type transcriptional regulator Rv0494 Rv0603 (family_assigned) — hypothetical protein Rv0603 Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR nadE (requalified) — NAD(+) synthase nadE Rv1152 (family_assigned) — GntR family transcriptional regulator Rv1152 pncA (requalified) — pyrazinamidase PncA pncA nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA vapC47 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC47 vapB47 (requalified) — antitoxin VapB47 vapB47 Rv0147 (requalified) — aldehyde dehydrogenase Rv0147 Rv0458 (family_assigned) — aldehyde dehydrogenase family protein Rv0458 aldC (requalified) — aldehyde dehydrogenase AldC aldC Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr oxyS (family_assigned) — LysR family transcriptional regulator OxyS oxyS Rv1674c (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv1674c mmr (requalified) — multidrug resistance protein Mmr mmr sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c Rv1167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1167c tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA Rv1176c (family_assigned) — PadR family transcriptional regulator Rv1176c iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR parE1 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to parE1 vapC30 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC30 lrpA (family_assigned) — transcriptional regulator LrpA lrpA Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c Rv1773c (family_assigned) — IclR family transcriptional regulator Rv1773c Rv1931c (family_assigned) — transcriptional regulator Rv1931c Rv0792c (family_assigned) — GntR family transcriptional regulator Rv0792c lpqO (family_assigned) — DUF1259 domain-containing protein lpqO

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.