MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3392c · 46 genes shown · anchor iunH · open gene page → · ← back to 1 hop

Evidence: Min score 0
cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c iunH (requalified) — nucleoside hydrolase IunH iunH Rv0448c (dark) — hypothetical protein Rv0448c pks13 (requalified) — polyketide synthase Pks13 pks13 Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c Rv3254 (requalified) — oxidoreductase Rv3254 Rv1523 (requalified) — class I SAM-dependent methyltransferase Rv1523 lppM (requalified) — lipoprotein LppM lppM Rv0236A (dark) — hypothetical protein Rv0236A amiA1 (requalified) — N-acyl-L-amino acid amidohydrolase AmiA amiA1 Rv3787c (requalified) — class I SAM-dependent methyltransferase Rv3787c ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 deoD (requalified) — purine-nucleoside phosphorylase deoD adoK (family_assigned) — carbohydrate kinase family protein adoK pncA (requalified) — pyrazinamidase PncA pncA add (requalified) — adenosine deaminase add cobB (requalified) — NAD-dependent protein deacylase cobB apt (requalified) — adenine phosphoribosyltransferase apt rskA (requalified) — anti-sigma-K factor RskA rskA mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 metH (requalified) — methionine synthase metH metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE Rv3015c (requalified) — methionine synthase Rv3015c idsA2 (requalified) — bifunctional (2E%2C6E)-farnesyl/geranyl diphosphat idsA2 metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metB (requalified) — cystathionine gamma-synthase metB ptrp (family_assigned) — hypothetical protein ptrp iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR Rv2164c (family_assigned) — hypothetical protein Rv2164c erg3 (requalified) — membrane-bound C-5 sterol desaturase erg3 ureD (requalified) — urease accessory protein UreD ureD Rv3732 (dark) — DUF2330 domain-containing protein Rv3732 Rv1524 (requalified) — glycosyltransferase Rv1524 wbbL2 (family_assigned) — glycosyltransferase family 2 protein wbbL2 mmpL12 (requalified) — RND transporter MmpL12 mmpL12 menH (requalified) — demethylmenaquinone methyltransferase menH

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.