MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3357 · 46 genes shown · anchor relK · open gene page → · ← back to 1 hop

Evidence: Min score 0
relJ (requalified) — type II toxin-antitoxin system antitoxin RelJ relJ relK (family_assigned) — Txe/YoeB family addiction module toxin relK Rv3359 (requalified) — NADH:flavin oxidoreductase Rv3359 folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD Rv3355c (dark) — DUF3017 domain-containing protein Rv3355c sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR Rv3360 (family_assigned) — FHA domain-containing protein Rv3360 relG (family_assigned) — type II toxin-antitoxin system RelE/ParE family to relG relE (requalified) — type II toxin-antitoxin system mRNA interferase Re relE clpP1 (family_assigned) — ATP-dependent CLP protease proteolytic subunit 1 clpP1 Rv3749c (family_assigned) — hypothetical protein Rv3749c mazF4 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF4 lexA (requalified) — transcriptional repressor LexA lexA relB (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant relB relF (requalified) — type II toxin-antitoxin system antitoxin RelF relF Rv0268c (family_assigned) — hypothetical protein Rv0268c Rv0310c (family_assigned) — nuclear transport factor 2 family protein Rv0310c Rv3169 (family_assigned) — hypothetical protein Rv3169 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH purN (requalified) — phosphoribosylglycinamide formyltransferase purN gcvT (requalified) — aminomethyltransferase gcvT fmt (requalified) — methionyl-tRNA formyltransferase fmt lprD (family_assigned) — hypothetical protein lprD Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c Rv1019 (family_assigned) — TetR/AcrR family transcriptional regulator Rv1019 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c pknB (family_assigned) — Stk1 family PASTA domain-containing Ser/Thr kinase pknB Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c Rv1277 (family_assigned) — hypothetical protein Rv1277 Rv1278 (family_assigned) — AAA family ATPase Rv1278 cut3 (family_assigned) — cutinase family protein cut3 mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 Rv2864c (family_assigned) — penicillin-binding protein Rv2864c Rv1245c (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv1245c clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 clpX (family_assigned) — ATP-dependent Clp protease ATP-binding subunit Clp clpX tig (requalified) — trigger factor tig clpC1 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.