Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3256c · 45 genes shown · anchor manA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3256c (requalified) — TobH protein Rv3256c manA (requalified) — mannose-6-phosphate isomerase%2C class I manA pmmA (requalified) — phosphomannomutase/phosphoglucomutase pmmA cei (requalified) — envelope integrity protein Cei cei Rv2732c (family_assigned) — hypothetical protein Rv2732c Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 Rv0358 (requalified) — peptidase M50 Rv0358 Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv2325c (family_assigned) — CbiQ family ECF transporter T component Rv2325c Rv3212 (family_assigned) — hypothetical protein Rv3212 lpqW (requalified) — lipoarabinomannan biosynthesis protein LpqW lpqW Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv3438 (family_assigned) — alpha/beta hydrolase Rv3438 pgi (requalified) — glucose-6-phosphate isomerase pgi pfkB (family_assigned) — 1-phosphofructokinase family hexose kinase pfkB pmmB (requalified) — phospho-sugar mutase pmmB glmS (requalified) — glutamine--fructose-6-phosphate transaminase (isom glmS manB (requalified) — D-alpha-D-mannose-1-phosphate guanylyltransferase manB glgP (family_assigned) — glycosyltransferase family 1 protein glgP Rv3259 (family_assigned) — metallopeptidase family protein Rv3259 Rv1109c (requalified) — lipid droplet-associated protein Rv1109c Rv2091c (family_assigned) — DUF4333 domain-containing protein Rv2091c miaB (requalified) — tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiot miaB Rv3205c (family_assigned) — hypothetical protein Rv3205c menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD bpoC (family_assigned) — alpha/beta hydrolase bpoC mgtA (requalified) — GDP-mannose-dependent alpha-mannosyltransferase mgtA Rv1632c (family_assigned) — DUF402 domain-containing protein Rv1632c Rv0359 (family_assigned) — site-2 protease family protein Rv0359 purA (requalified) — adenylosuccinate synthase purA Rv3217c (dark) — hypothetical protein Rv3217c Rv3851 (dark) — hypothetical protein Rv3851 espR (family_assigned) — type VII secretion system ESX-1 transcriptional re espR Rv2326c (family_assigned) — ABC transporter ATP-binding protein Rv2326c Rv2327 (family_assigned) — MarR family winged helix-turn-helix transcriptiona Rv2327 dppD (family_assigned) — ABC transporter ATP-binding protein dppD Rv1634 (requalified) — MFS transporter Rv1634 Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 rhlE (requalified) — DEAD/DEAH box helicase rhlE lppL (family_assigned) — hypothetical protein lppL typA (requalified) — translational GTPase TypA typA folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC valS (requalified) — valine--tRNA ligase valS Rv0863 (family_assigned) — hypothetical protein Rv0863 Rv3437 (dark) — DUF2510 domain-containing protein Rv3437

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.