MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3247c · 46 genes shown · anchor mtrA · open gene page → · ← back to 1 hop

Evidence: Min score 0
tmk (requalified) — dTMP kinase tmk dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ thyX (requalified) — FAD-dependent thymidylate synthase thyX thyA (requalified) — thymidylate synthase ThyA thyA ndkA (requalified) — nucleoside-diphosphate kinase ndkA nrdB (requalified) — R2-like ligand-binding oxidase nrdB nrdF1 (family_assigned) — ribonucleoside-diphosphate reductase subunit beta nrdF1 nrdF2 (family_assigned) — ribonucleoside-diphosphate reductase subunit beta nrdF2 mtrA (requalified) — two-component system response regulator MtrA mtrA sahH (requalified) — adenosylhomocysteinase sahH lpqB (requalified) — MtrAB system accessory lipoprotein LpqB lpqB lprE (family_assigned) — LppP/LprE family lipoprotein lprE dcd (requalified) — dCTP deaminase dcd nrdH (requalified) — redoxin NrdH nrdH nrdI (requalified) — class Ib ribonucleoside-diphosphate reductase asse nrdI Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 cmk (requalified) — (d)CMP kinase cmk dfrA (requalified) — dihydrofolate reductase dfrA glyA2 (requalified) — serine hydroxymethyltransferase glyA2 purN (requalified) — phosphoribosylglycinamide formyltransferase purN glyA1 (requalified) — serine hydroxymethyltransferase glyA1 folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD rpsJ (requalified) — 30S ribosomal protein S10 rpsJ rpsL (requalified) — 30S ribosomal protein S12 rpsL rpsO (requalified) — 30S ribosomal protein S15 rpsO rpsB (requalified) — 30S ribosomal protein S2 rpsB rpsG (requalified) — 30S ribosomal protein S7 rpsG rpsP (requalified) — 30S ribosomal protein S16 rpsP Rv0232 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0232 Rv3047c (dark) — hypothetical protein Rv3047c mtrB (requalified) — two-component system sensor histidine kinase MtrB mtrB Rv0600c (requalified) — two component sensor kinase HK1 Rv0600c trcS (family_assigned) — HAMP domain-containing sensor histidine kinase trcS senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3 tcrY (requalified) — two component sensor kinase TcrY tcrY prrB (requalified) — two-component system sensor histidine kinase PrrB prrB metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metH (requalified) — methionine synthase metH cbs (requalified) — cystathionine beta-synthase cbs metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metB (requalified) — cystathionine gamma-synthase metB mtn (requalified) — 5'-methylthioadenosine/adenosylhomocysteine nucleo mtn Rv3243c (family_assigned) — LmeA family phospholipid-binding protein Rv3243c Rv3802c (requalified) — phospholipase Rv3802c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.