MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3223c · 46 genes shown · anchor rshA · open gene page → · ← back to 1 hop

Evidence: Min score 0
sigH (family_assigned) — sigma-70 family RNA polymerase sigma factor SigH sigH rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC rshA (requalified) — anti-sigma factor RshA rshA Rv3222c (family_assigned) — hypothetical protein Rv3222c rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ sigC (requalified) — RNA polymerase sigma factor SigC sigC TB7.3 (requalified) — biotin/lipoyl-binding carrier protein TB7.3 Rv3224 (requalified) — NAD(P)-dependent oxidoreductase Rv3224 Rv3224B (family_assigned) — Conserved hypothetical protein Rv3224B Rv3220c (family_assigned) — histidine kinase N-terminal domain-containing prot Rv3220c pknB (family_assigned) — Stk1 family PASTA domain-containing Ser/Thr kinase pknB sigA (requalified) — RNA polymerase sigma factor sigA sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB sigL (family_assigned) — sigma-70 family RNA polymerase sigma factor SigL sigL whiB7 (family_assigned) — transcriptional regulator WhiB7 whiB7 moeB1 (requalified) — adenylyltransferase/sulfurtransferase MoeZ moeB1 rpsM (requalified) — 30S ribosomal protein S13 rpsM rpsH (requalified) — 30S ribosomal protein S8 rpsH rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA helZ (requalified) — DEAD/DEAH box helicase helZ Rv0093c (family_assigned) — membrane protein Rv0093c sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM blaC (requalified) — beta-lactamase blaC Rv2067c (requalified) — class I SAM-dependent methyltransferase Rv2067c accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 glcB (requalified) — malate synthase G glcB acs (requalified) — acetate--CoA ligase acs leuA (requalified) — 2-isopropylmalate synthase leuA Rv3224A (family_assigned) — Conserved hypothetical protein Rv3224A fas (requalified) — fatty acid synthase fas fadE25 (requalified) — acyl-CoA dehydrogenase fadE25 Rv0227c (family_assigned) — membrane protein Rv0227c aspS (requalified) — aspartate--tRNA ligase aspS Rv1626 (family_assigned) — ANTAR domain-containing response regulator Rv1626 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 whiB2 (family_assigned) — transcriptional regulator WhiB2 whiB2 pstP (requalified) — phosphoserine/threonine phosphatase PstP pstP pknA (requalified) — serine/threonine protein kinase PknA pknA garA (requalified) — glycogen accumulation regulator GarA garA fhaA (requalified) — cell division-associated protein FhaA fhaA fhaB (family_assigned) — FHA domain-containing protein fhaB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.