MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3221A · 46 genes shown · anchor sigH · open gene page → · ← back to 1 hop

Evidence: Min score 0
rshA (requalified) — anti-sigma factor RshA rshA sigH (family_assigned) — sigma-70 family RNA polymerase sigma factor SigH sigH Rv3222c (family_assigned) — hypothetical protein Rv3222c TB7.3 (requalified) — biotin/lipoyl-binding carrier protein TB7.3 Rv3224 (requalified) — NAD(P)-dependent oxidoreductase Rv3224 Rv3224B (family_assigned) — Conserved hypothetical protein Rv3224B moeB1 (requalified) — adenylyltransferase/sulfurtransferase MoeZ moeB1 whiB4 (family_assigned) — transcriptional regulator WhiB4 whiB4 sigD (requalified) — ECF RNA polymerase sigma factor SigD sigD bpa (requalified) — proteasome activator protein Bpa bpa Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 pstP (requalified) — phosphoserine/threonine phosphatase PstP pstP Rv3220c (family_assigned) — histidine kinase N-terminal domain-containing prot Rv3220c rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 glcB (requalified) — malate synthase G glcB acs (requalified) — acetate--CoA ligase acs leuA (requalified) — 2-isopropylmalate synthase leuA Rv3224A (family_assigned) — Conserved hypothetical protein Rv3224A fas (requalified) — fatty acid synthase fas fadE25 (requalified) — acyl-CoA dehydrogenase fadE25 Rv0227c (family_assigned) — membrane protein Rv0227c aspS (requalified) — aspartate--tRNA ligase aspS moaX (requalified) — MoaD-MoaE fusion protein MoaX moaX cysO (requalified) — sulfur carrier protein CysO cysO iscS (family_assigned) — cysteine desulfurase family protein iscS moaD2 (family_assigned) — molybdopterin synthase subunit MoaD2 moaD2 moaD1 (requalified) — molybdenum cofactor biosynthesis protein MoaD moaD1 moeB2 (requalified) — molybdenum cofactor biosynthesis protein MoeB moeB2 apt (requalified) — adenine phosphoribosyltransferase apt secG (family_assigned) — preprotein translocase subunit SecG secG Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 Rv0525 (family_assigned) — histidine phosphatase family protein Rv0525 rsdA (requalified) — anti-sigma D factor RsdA rsdA Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c Rv3415c (family_assigned) — hypothetical protein Rv3415c ripA (family_assigned) — NlpC/P60 family peptidoglycan endopeptidase RipA ripA pirG (requalified) — exported repetitive protein pirG Rv3717 (family_assigned) — hypothetical protein Rv3717 prcA (family_assigned) — proteasome subunit alpha prcA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.