Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3214 · 46 genes shown · anchor thyA · open gene page → · ← back to 1 hop

Evidence: Min score 0
gpm2 (requalified) — phosphoglycerate mutase gpm2 thyA (requalified) — thymidylate synthase ThyA thyA entC (requalified) — isochorismate synthase entC Rv3213c (family_assigned) — AAA family ATPase Rv3213c pfkA (requalified) — ATP-dependent 6-phosphofructokinase pfkA pgi (requalified) — glucose-6-phosphate isomerase pgi fba (requalified) — class II fructose-bisphosphate aldolase fba ppnK (requalified) — NAD kinase ppnK cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ pfkB (family_assigned) — 1-phosphofructokinase family hexose kinase pfkB nudC (requalified) — NAD(+) diphosphatase nudC Rv2135c (family_assigned) — histidine phosphatase family protein Rv2135c cobQ1 (requalified) — cobyric acid synthase cobQ1 dfrA (requalified) — dihydrofolate reductase dfrA thyX (requalified) — FAD-dependent thymidylate synthase thyX dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD tmk (requalified) — dTMP kinase tmk glyA1 (requalified) — serine hydroxymethyltransferase glyA1 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD mbtI (requalified) — salicylate synthase mbtI mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA aroF (requalified) — chorismate synthase aroF Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c parB (family_assigned) — ParB/RepB/Spo0J family partition protein parB Rv2647 (requalified) — hypothetical protein Rv2647 ftsK (requalified) — DNA translocase FtsK ftsK dnaA (requalified) — chromosomal replication initiator protein DnaA dnaA guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA tkt (requalified) — transketolase tkt tal (requalified) — transaldolase tal tpi (requalified) — triose-phosphate isomerase tpi pgmA (requalified) — phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosp pgmA pykA (requalified) — pyruvate kinase pykA gap (requalified) — type I glyceraldehyde-3-phosphate dehydrogenase gap eno (requalified) — phosphopyruvate hydratase eno tlyA (requalified) — 16S/23S rRNA (cytidine-2'-O)-methyltransferase Tly tlyA nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD nadE (requalified) — NAD(+) synthase nadE nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR cobB (requalified) — NAD-dependent protein deacylase cobB pntB (family_assigned) — NAD(P)(+) transhydrogenase (Re/Si-specific) subuni pntB cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobH (requalified) — precorrin-8X methylmutase cobH cobK (requalified) — cobalt-precorrin-6A reductase cobK

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.