MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3141 · 46 genes shown · anchor pks15 · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 htdZ (requalified) — 3-hydroxyacyl-thioester dehydratase HtdZ htdZ pks9 (requalified) — type I polyketide synthase pks9 fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 fadE24 (family_assigned) — acyl-CoA dehydrogenase family protein fadE24 fadE36 (family_assigned) — phosphotransferase family protein fadE36 fadE2 (requalified) — acyl-CoA dehydrogenase fadE2 pks6 (requalified) — membrane bound polyketide synthase pks6 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pflA (requalified) — AmmeMemoRadiSam system radical SAM enzyme pflA pks1 (requalified) — polyketide synthase pks1 pks17 (requalified) — polyketide synthase pks17 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtE (requalified) — peptide synthetase mbtE mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtF (requalified) — peptide synthetase mbtF papA3 (requalified) — acyltransferase PapA3 papA3 Rv3777 (requalified) — oxidoreductase Rv3777 Rv0149 (family_assigned) — NADPH:quinone oxidoreductase family protein Rv0149 fadE30 (family_assigned) — acyl-CoA dehydrogenase family protein fadE30 fadE17 (requalified) — acyl-CoA dehydrogenase fadE17 icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 pks7 (requalified) — type I polyketide synthase pks7 pks8 (requalified) — polyketide synthase pks8 fadB5 (family_assigned) — medium chain dehydrogenase/reductase family protei fadB5 ltp1 (requalified) — lipid-transfer protein ltp1 fadB (requalified) — fatty oxidation protein FadB fadB accD1 (family_assigned) — acetyl-/propionyl-CoA carboxylase subunit beta accD1 fadE7 (requalified) — acyl-CoA dehydrogenase fadE7 echA6 (requalified) — enoyl-CoA hydratase echA6 fixA (family_assigned) — electron transfer flavoprotein subunit beta/FixA f fixA fixB (family_assigned) — electron transfer flavoprotein subunit alpha/FixB fixB fadE16 (family_assigned) — acyl-CoA dehydrogenase family protein fadE16 fadE1 (requalified) — acyl-CoA dehydrogenase FadE1 fadE1 Rv2766c (requalified) — short-chain type dehydrogenase/reductase Rv2766c Rv3168 (family_assigned) — phosphotransferase family protein Rv3168 Rv3762c (requalified) — alkyl/aryl-sulfatase Rv3762c ptbB (requalified) — tyrosine-protein phosphatase PtbB ptbB fas (requalified) — fatty acid synthase fas

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.